Virulence Factors and pap Genotype in Escherichia coli Isolates from Women with Acute Pyelonephritis, with or without Bacteremia

Clinical Infectious Diseases

Volumn 17, Issue 3, 1993, Pages 448-456

  Otto, Gisela ^a,b,c   Sandberg, Torsten ^a,b,c   Marklund, Britt Inger ^a,b,c   Ulleryd, Peter ^a,b,c   Svanborg, Catharina ^a,b,c  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; AEROBACTIN; DNA; HEMOLYSIN;

ACUTE PHASE RESPONSE; ACUTE PYELONEPHRITIS; ADULT; AGE; AGED; ARTICLE; BACTEREMIA; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BACTERIUM ISOLATION; BLOOD CULTURE; CONTROLLED STUDY; DNA SEQUENCE; ESCHERICHIA COLI; FEMALE; FIMBRIA; GENOTYPE; HOST RESISTANCE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK; SEROTYPING; SERUM BACTERICIDAL ACTIVITY; URINE CULTURE;

ACUTE DISEASE; ADHESINS, ESCHERICHIA COLI; ADULT; AGE FACTORS; ANTIGENS, BACTERIAL; BACTEREMIA; BACTERIAL OUTER MEMBRANE PROTEINS; DNA, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; GENOTYPE; HUMAN; MIDDLE AGE; PYELONEPHRITIS; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; VIRULENCE;

EID: 0027282544     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/clinids/17.3.448     Document Type: Article

References (45)

1. Safrin S, Siegel D, Black D. Pyelonephritis in adult women: inpatient versus outpatient therapy. Am J Med 1988;85:793-8.
2. Gleckman RA, Bradley PJ, Roth RM, Hibert DM. Bacteremic urosepsis: a phenomenon unique to elderly women. J Urol 1985;133:174-5.
3. Murdoch JM, Speirs CF, Geddes AM, Wright N, Wallace ET. Treatment of recurrent urinary tract infection. In: O'Grady F, Brumfitt W, eds. Urinary tract infection. London: Oxford University Press, 1968:27-34.
4. Grover SA, Komaroff AL, Weisberg M, Cook EF, Goldman L. The characteristics and hospital course of patients admitted for presumed acute pyelonephritis. J Gen Intern Med 1987;2:5-10.
5. Sandberg T, Englund G, Lincoln K, Nilsson L-G. Randomised doubleblind study of norfloxacin and cefadroxil in the treatment of acute pyelonephritis. Eur J Clin Microbiol Infect Dis 1990;9:317-23.
6. Johnson JR, Lyons MF II, Pearce W, et al. Therapy for women hospitalized with acute pyelonephritis: a randomized trial of ampicillin versus trimethoprim-sulfamethoxazole for 14 days. J Infect Dis 1991;163:325-30.
7. Johnson JR, Roberts PL, Stamm WE. P fimbriae and other virulence factors in Escherichia coli urosepsis: association with patients' characteristics. J Infect Dis 1987;156:225-9.
8. Johnson JR. Virulence factors in Escherichia coli urinary tract infection. Clin Microbiol Rev 1991;4:80-128.
9. Mabeck CE, Orskov F, Orskov I. Escherichia coli serotypes and renal involvement in urinary-tract infection. Lancet 1971;1:1312-4.
10. Caugant DA, Levin BR, Lidin-Janson G, Whittam TS, Svanborg-Eden C, Selander RK. Genetic diversity and relationships among strains of Escherichia coli in the intestine and those causing urinary tract infections. Prog Allergy 1983;33:203-27.
11. Brauner A, Leissner M, Wretlind B, Julander I, Svenson SB, Kallenius G. Occurrence of P-fimbriated Escherichia coli in patients with bacteremia. Eur J Clin Microbiol 1985;4:566-9.
12. Arthur M, Johnson CE, Rubin RH, et al. Molecular epidemiology of adhesiri and hemolysin virulence factors among uropathogenic Escherichia coli. Infect Immun 1989;57:303-13.
13. Svanborg-Eden C, Hansson S, Jodal U, et al. Host-parasite interaction in the urinary tract. J Infect Dis 1988;157:421-6.
14. Orskov I, Svanborg-Eden C, Orskov F. Aerobactin production of serotyped Escherichia coli from urinary tract infections. Med Microbiol Immunol 1988;177:9-14.
15. Hughes C, Hacker J, Roberts A, Goebel W. Hemolysin production as a virulence marker in symptomatic and asymptomatic urinary tract infections caused by Escherichia coli. Infect Immun 1983;39:546-51
16. 011ing S, Hanson LA, Holmgren J, Jodal U, Lincoln K, Lindberg U. The bactericidal effect of normal human serum on E. coli strains from normals and from patients with urinary tract infections. Infection 1973;1:24-8.
17. Vaisanen-Rhen V, Elo J, Vaisanen E, et al. P-fimbriated clones among uropathogenic Escherichia coli strains. Infect Immun 1984;43:149-55
18. Leffler H, Svanborg-Edên C. Glycolipid receptors for uropathogenic Escherichia coli on human erythrocytes and uroepithelial cells. Infect Immun 1981;34:920-9.
19. Vaisanen V, Elo J, Tallgren LG, et al. Mannose-resistant haemagglutination and P antigen recognition are characteristic of Escherichia coli causing primary pyelonephritis. Lancet 1981;2:1366-9.
20. Hull RA, Gill RE, Hsu P, Minshew BH, Falkow S. Construction and expression of recombinant plasmids encoding type 1 or D-mannoseresistant pili from a urinary tract infection Escherichia coli isolate. Infect Immun 1981;33:933-8.
21. Rhen M, Knowles J, Penttila ME, Sarvas M, Korhonen TK. P fimbriae of Escherichia coli. molecular cloning of DNA fragments containing the structural genes. FEMS Microbiol Lett 1983;19:119-23.
22. Lund B, Lindberg F, Marklund B-I, Normark S. The pap G protein is the a-D-galactopyranosyl-(1 4)-#-D-galactopyranose-binding adhesin of uropathogenic Escherichia coli. Proc Natl Acad Sci USA 1987;84:5898-902.
23. Lund B, Marklund B-I, StrOmberg N, Lindberg F, Karlsson KA, Normark S. Uropathogenic Escherichia coli can express serologically identical pili of different receptor binding specificities. Mol Microbiol 1988;2:255-63.
24. StrOmberg N, Marklund B-I, Lund B, et al. Host-specificity of uropathogenic Escherichia coli depends on differences in binding specificity to Gala1-4Galfl-containing isoreceptors. EMBO J 1990;9:2001-10.
25. Lindstedt R, Baker N, Falk P, et al. Binding specificities of wild-type and cloned Escherichia coli strains that recognize globo-A. Infect Immun 1989;57:3389-94.
26. Johanson I, Lindstedt R, Svanborg C. Roles of the pap- and prs-encoded adhesins in Escherichia coli adherence to human uroepithelial cells. Infect Immun 1992;60:3416-22.
27. Sandberg T, Kaijser B, Lidin-Janson G, et al. Virulence of Escherichia coli in relation to host factors in women with symptomatic urinary tract infection. J Clin Microbiol 1988;26:1471-6.
28. Sandberg T, Stokland E, Brolin I, Lidin-Janson G, Svanborg-Eden C. Selective use of excretory urography in women with acute pyelonephritis. J Urol 1989;141:1290-4.
29. Orskov F, Orskov I. Serotyping of Escherichia coli. In: Bergan T, ed. Methods in microbiology. Vol 14. London: Academic Press, 1984:43-112.
30. Lidin-Janson G, Falsen E, Jodal U, Kaijser B, Lincoln K. Characteristics of antibiotic-resistant Escherichia coli in the rectum of healthy school-children. J Med Microbiol 1977;10:299-308.
31. Jacobson SH, Tullus K, Wretlind B, Brauner A. Aerobactin-mediated uptake ofiron by strains ofEscherichia coli causing acute pyelonephritis and bactaeremia. J Infect 1988;16:147-52.
32. Svanborg Eden C, Eriksson B, Hanson LA. Adhesion ofEscherichia coli to human uroepithelial cells in vitro. Infect Immun 1977;18:767-74.
33. Plos K, Carter T, Hull S, Hull R, Svanborg-Eden C. Frequency and organization of pap homologous DNA in relation to clinical origin of uropathogenic Escherichia coli. J Infect Dis 1990;161:518-24.
34. Ekback G, MOrner S, Lund D, Normark S. Correlation of genes in the pap gene cluster to expression of globoside-specific adhesin by uropathogenic Escherichia coll. FEMS Microbiol Lett 1986;34:355-60.
35. Plos K. P-fimbrial genotype, phenotype and clonal variation in Escherichia coli from the urinary tract and the fecal flora [thesis]. Goteborg, Sweden: University of Goteborg, 1992.
36. Hedges S, Svensson M, Svanborg C. Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro. Infect Immun 1992;60:1295-301.
37. Linder H, Engberg I, Hoschiltzky H, Mattsby-Baltzer I, Svanborg C. Adhesion-dependent activation of mucosal interleukin 6 production. Infect Immun 1991;59:4357-62.
38. Warren JW, Mobley HLT, Trifillis AL. Internalization of Escherichia coli into human renal tubular epithelial cells. J Infect Dis 1988;158:221-3.
39. Opal SM, Cross AS, Gemski P, Lyhte LW. Aerobactin and a-hemolysin as virulence determinants in Escherichia coli isolated from human blood, urine, and stool. J Infect Dis 1990;161:794-6.
40. O'Hanley P, Low D, Romero I, et al. Gal-Gal binding and hemolysin phenotypes and genotypes associated with uropathogenic Escherichia coli. N Engl J Med 1985;313:414-20.
41. Elgefors B, Oiling S. The significance of serum-sensitive bacilli in gramnegative bacteremia. Scand J Infect Dis 1978;10:203-7.
42. Lindstedt R, Larson G, Falk P, Jodal U, Leffler H, Svanborg C. The receptor repertoire defines the host range for attaching Escherichia coli strains that recognize globo-A. Infect Immun 1991;59:1086-92.
43. Agace W Hedges S, Ceska M, Svanborg C. Interleukin-8 and the neutrophil response in mucosal gram-negative infections. J Clin Invest 1993 (in press).
44. Hedges S, Stenqvist K, Lidin-Janson G, Martinell J, Sandberg T, Svanborg C. Comparison of urine and serum concentrations of interleukin- 6 in women with acute pyelonephritis or asymptomatic bacteriuria. J Infect Dis 1992;166:653-6.
45. de Man P, Jodal U, Lincoln K, Svanborg-Eden CS. Bacterial attachment and inflammation in the urinary tract. J Infect Dis 1988;158:29-35.