Practice guideline for the management of infants and children 0 to 36 months of age with fever without source

Annals of Emergency Medicine

Volumn 22, Issue 7, 1993, Pages 1198-1210

  Baraff, Larry J ^a   Bass, James W ^b   Fleisher, Gary R ^c   Klein, Jerome O ^d   McCracken Jr , George H ^e   Powell, Keith R ^f   Schriger, David L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TRIPLER ARMY MEDICAL CENTER   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d BOSTON MEDICAL CENTER   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f UNIVERSITY OF ROCHESTER   (United States)

Author keywords

fever; pediatric

Indexed keywords

ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BLOOD CULTURE; FECES CULTURE; HUMAN; INFANT; LEUKOCYTE COUNT; LUMBAR PUNCTURE; PRESCHOOL CHILD; PRIORITY JOURNAL; PYREXIA IDIOPATHICA; THORAX RADIOGRAPHY; URINALYSIS; URINE CULTURE;

ALGORITHMS; CHILD, PRESCHOOL; FEMALE; FEVER OF UNKNOWN ORIGIN; HUMAN; INFANT; INFANT, NEWBORN; MALE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027270519     PISSN: 01960644     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-0644(05)80991-6     Document Type: Article

References (112)

1. Bacterial meningitis: A symposium
2. Risk factors in bacterial meningitis: Charleston County, South Carolina
3. Incidence and prognosis of Haemophilus influenzae meningitis in children in a Swedish region
4. A study of illness in a group of Cleveland families. IV: The spread of respiratory infections within the home
5. Bacteremia in febrile children seen in a “walk-in” pediatric clinic
6. Blood cultures in the management of febrile outpatients later found to have bacteremia
7. Relative importance of bacteremia and viremia in the course of acute fevers of unknown origin in outpatient children
8. Bacteremia with otitis media
9. Blood cultures in private pediatric practice: An eleven-year experience
10. Outcome of unsuspected pneumococcemia in children not initially admitted to the hospital
11. Occult bacteremia in the emergency department: Diagnostic criteria for the young febrile child
12. A comparative study of the prevalence, outcome and prediction of bacteremia in children
13. Reevaluation of the ambulatory pediatric patient whose blood culture is positive for Haemophilus influenzae type b
14. Bacteremia in 28 ambulatory children
15. Antibiotic administration to treat possible occult bacteremia in febrile children
16. Unsuspected bacteremia due to Haemophilus influenzae: Outcome in children not initially admitted to hospital
17. Occult bacteremia in toxic appearing, febrile infants: A prospective clinical study in an office setting
18. Risk factors for development of bacterial meningitis among children with occult bacteremia
19. Management of the febrile child: A survey of pediatric and emergency medicine residency directors
20. Body temperature variations in apparent healthy children
21. Axillary temperature as a screening test for fever in children
22. Bacteremia in children afebrile at presentation to an emergency department
23. Incidence of serious infections in afebrile neonates with a history of fever
24. Probability of bacterial infections in infants less than three months of age: A meta-analysis
25. History and observation variables in assessing febrile children
26. An index of severity for acute pediatric illness
27. Outpatient bacteremia Clinical findings in children under two years with initial temperatures of 395 C or higher
28. Observation scales to identify serious illness in febrile children
29. Predictive value of abnormal physical examination findings in ill-appearing and well-appearing febrile children
30. Failure of infant observation scales in detecting serious illness in febrile 4- to 8-week-old infants
31. The evaluation and treatment of the febrile infant
32. Febrile infants: Predictors of bacteremia
33. Which febrile infants younger than two weeks of age are likely to have sepsis? A pilot study
34. Fever in the first eight weeks of life
35. Difficulties in universal application of criteria identifying infants at low risk for serious bacterial infection
36. Febrile infants less tha eight weeks old: Predictors of infection
37. Hospitalization and outpatient treatment of young, febrile infants
38. Management of febrile outpatient neonates
39. Evaluation of fever in infants less than 8 weeks old
40. Assessing the significance of fever in young infants—The diagnostic and prognostic value of cerebrospinal fluid and other clinical and laboratory findings
41. Detection of neonatal sepsis of late onset
42. Evaluation of the necessity for hospitalization of the febrile infant less than three months of age
43. Management of febrile outpatient neonates
44. Ambulatory care of febrile infants younger than 2 months of age classified as being at low risk for having serious bacterial infections
45. Outpatient management of selected infants younger than two months of age evaluated for possible sepsis
46. Identification of infants unlikely to have serious bacterial infection although hospitalized for suspected sepsis
47. Evaluation and management of febrile infants younger than 60 days of age
48. Outpatient management of febrile infants 28–90 days of age with intramuscular ceftriaxone
49. Management of infants at risk for occult bacteremia: A decision analysis
50. Bacterial and viral pathogens causing fever in infants less than 3 months old
51. Ceftriaxone: A reappraisal of its antibacterial activity and pharmacokinetic properties, and an update on its therapeutic use with particular reference to once-daily administration
52. Selecting diagnostic tests to identify febrile infants less than 3 months of age as being at low risk for serious bacterial infection: A scientific overview
53. Characteristics and management of febrile young children seen in a university family practice
54. Bacteremia in febrile children under 2 years of age: Results of cultures of blood of 600 consecutive febrile children seen in a “walk-in” clinic
55. Treatment of occult bacteremia: A prospective randomized clinical trial
56. Evaluation of children with fever greater than or equal to 104 degrees F in an emergency department
57. Diplococcus pneumoniae bacteremia
58. Pneumococcal bacteremia in pediatric patients
59. Relationship of bacteremia to antipyretic therapy in febrile children
60. Hyperpyrexia in children: Eight-year emergency room experience
61. Association of temperature greater than 41.1° C (106° F) with serious illness
62. Immunization with oligosaccharide conjugate Haemophilus influenzae type b (HbOC) vaccine on a large health maintenance organization population: Extended follow-up and impact on Haemophilus influenzae disease epidemiology. The Kaiser Permanente Pediatric Vaccine Study Group
63. Efficacy and safety of a Haemophilus influenzae type b capsular polysaccharide-tetanus protein conjugate vaccine
64. Rapid disappearance of Haemophilus influenzae type b meningitis after routine childhood immunisation with conjugate vaccines
65. Efficacy of Haemophilus influenzae type b vaccines in Massachusetts children 18 to 59 months of age
66. Decline in Haemophilus influenzae type b disease in the Hib vaccine era
67. Decreases in invasive Haemophilus influenzae disease in US Army children 1984 through 1991
68. Declining incidence of Haemophilus influenzae type b disease since introduction of vaccination
69. Further definition of history and observation variables in assessing febrile children
70. Observation, history and physical examination in diagnosis of illnesses in febrile children ≤ 24 months
71. Fever without source: Management of children 3 to 36 months of age
72. C-reactive protein and zeta sedimentation ratio as indicators of bacteremia in pediatric patients
73. Early detection of bacteremia in an outpatient clinic
74. Comparison of acute-phase reactants in pediatric patients with fever
75. Value of the C-reactive protein test in the differentiation of bacterial and viral pneumonia
76. WBC count and differential: Value in predicting bacterial diseases in children
77. Viral and bacterial infection in childhood: The value of C reactive protein
78. Childhood infections: Diagnostic value of peripheral white blood cell and differential cell counts
79. Temperature and total white blood cell count as indicators of bacteremia
80. ‘Normal’ CSF in bacterial meningitis
81. Bacterial meningitis with initial normal cerebrospinal fluid findings
82. Urinary tract infections in febrile infants less than 8 weeks of age
83. Prevalence of bacteriuria in febrile children
84. Urinary tract infection in infants with unexplained fever: A collaborative study
85. Bacteruria in children with acute febrile illnesses
86. Making a presumptive diagnosis of urinary tract infection by using a urinalysis performed in an on-site laboratory
87. Clinical predictors of pneumonia as a guide to ordering chest roentgenograms
88. Chest radiographs in the evaluation of the febrile infant
89. Usefulness of chest radiographs in children with acute lower respiratory tract disease
90. Common clinical features as predictors of bacterial diarrhea in infants
91. Strategies for diagnosis and treatment of children at risk for occult bacteremia: Clinical effectiveness and cost-effectiveness
92. Nature and extent of penicillin side reactions with particular reference to fatalities from anaphylactic shock
93. Drug induced anaphylaxis, convulsions, deafness, and extrapyramidal symptoms
94. Relative resistance to penicillin in the pneumococcus: A prevalence and case-control study
95. Penicillin-intermediate pneumococci in a children's hospital
96. Antibiotic resistance and serotypes of 100 Streptococcus pneumoniae strains isolated in a children's hospital in Barcelona, Spain
97. Pneumococcal resistance to antibiotics
98. Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae isolates causing systemic infections in Spain, 1979–1989
99. Antibiotic-resistant pneumococcal disease in South African children
100. Increased rate of isolation of penicillin-resistant Streptococcus pneumoniae in a children's hospital and in vitro susceptibilities to antibiotics of potential therapeutic use
101. Systemic infections due to Streptococcus pneumoniae relatively resistant to penicillin in a children's hospital: Clinical management and outcome
102. Susceptibility of penicillin-resistant pneumococci to eighteen antimicrobials: Implications for treatment of meningitis
103. Pharmacokinetics and bacteriologic efficacy of moxalactam, cefotaxime, cefoperazone, and rocephin in experimental bacterial meningitis
104. Ceftriaxone failure in meningitis caused by Streptococcus pneumoniae with reduced susceptibility to beta-lactam antibiotics
105. Cephalosporin treatment failure in penicillin- and cephalosporin-resistant Streptococcus pneumoniae meningitis
106. A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone