Design of peptide enzymes (pepzymes): Surface-simulation synthetic peptides that mimic the chymotrypsin and trypsin active sites exhibit the activity and specificity of the respective enzyme

Proceedings of the National Academy of Sciences of the United States of America

Volumn 90, Issue 17, 1993, Pages 8282-8286

  Atassi, M Zouhair ^a   Manshouri, Taghi ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINAE; GLYCINE MAX;

ALPHA 1 ANTITRYPSIN; AMINO ACID; APROTININ; BENZYLSULFONYL FLUORIDE; CASEIN; CHYMOTRYPSIN A; DYFLOS; ESTER; MYOGLOBIN; PEPTIDE HYDROLASE; SOYBEAN TRYPSIN INHIBITOR; SYNTHETIC PEPTIDE; TOSYLARGININE METHYL ESTER; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TRYPSIN; TYROSINE;

ARTICLE; DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; BINDING SITES; CHYMOTRYPSIN; COMPARATIVE STUDY; DISULFIDES; DRUG DESIGN; KINETICS; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; TRYPSIN;

EID: 0027268487     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.90.17.8282     Document Type: Article

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