Novel Acyclonucleotides: Synthesis and Antiviral Activity of Alkenylphosphonic Acid Derivatives of Purines and a Pyrimidine

Journal of Medicinal Chemistry

Volumn 36, Issue 10, 1993, Pages 1343-1355

  Harnden, Michael R ^a   Parkin, Ann ^a   Parratt, Martin J ^a   Perkins, Robert M ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(1 HYDROXY 4 PHOSPHONOBUT 3 EN 2 YL)OXY]CYTOSINE; 2,6 DIAMINO 9 (4 PHOSPHONOBUT 3 ENYL)PURINE; 9 (2 METHYLENE 4 PHOSPHONOBUT 3 ENYL)GUANINE; 9 (4 PHOSPHONOBUT 3 ENYL)ADENINE; 9 (4 PHOSPHONOBUT 3 ENYL)GUANINE; 9 [(1 HYDROXY 4 PHOSPHONOBUT 3 EN 2 YL)OXY]ADENINE; 9 [(1 HYDROXY 4 PHOSPHONOBUT 3 EN 2 YL)OXY]GUANINE; 9 [(4 PHOSPHONOBUT 3 ENYL)OXY]ADENINE; 9 [(4 PHOSPHONOBUT 3 ENYL)OXY]GUANINE; 9 [2 (HYDROXYMETHYL) 4 PHOSPHONOBUT 3 ENYL]ADENINE; 9 [2 (HYDROXYMETHYL) 4 PHOSPHONOBUT 3 ENYL]GUANINE; ACYCLONUCLEOTIDE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CYTOMEGALOVIRUS; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; VARICELLA ZOSTER VIRUS; VIRUS INFECTION; VISNA VIRUS;

ANTIVIRAL AGENTS; CELLS, CULTURED; HERPESVIRIDAE; MICROBIAL SENSITIVITY TESTS; PHOSPHONIC ACIDS; PURINE NUCLEOTIDES; PYRIMIDINE NUCLEOTIDES; RETROVIRIDAE;

EID: 0027262421     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00062a006     Document Type: Article

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