The Gus-e locus regulates estrogen repression of androgen-induced β-glucuronidase expression in mouse kidney

Biochemical Genetics

Volumn 31, Issue 3, 1993, Pages 155-166

  Watson, Gordon ^a   Jaussi, Rolf ^b   Tabron, Dorothy ^c   Paigen, Kenneth ^a  

^a JACKSON LABORATORY   (United States)

^b PAUL SCHERRER INSTITUTE   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

gene regulation; regulatory locus; response to androgen; response to estrogen; glucuronidase

Indexed keywords

ANDROGEN; BETA GLUCURONIDASE; ESTROGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE LOCUS; HORMONE RESPONSE; KIDNEY; MOUSE; NONHUMAN;

ANDROGENS; ANIMAL; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCURONIDASE; HAPLOTYPES; KIDNEY; KINETICS; MICE; MICE, INBRED C57BL; RECEPTORS, ANDROGEN; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027258799     PISSN: 00062928     EISSN: 15734927     Source Type: Journal    
DOI: 10.1007/BF02399922     Document Type: Article

References (27)

1. Chemical kinetics of induced gene expression: Activation of transcription by noncooperative binding of multiple regulatory molecules
2. Gene regulation by steroid hormones
3. Changes in translational yield regulate tissue-specific expression of β-glucuronidase
4. The N haplotype of the β-glucuronidase gene is altered in both its systemic regulation and its response to androgen induction
5. Weak androgen reduces the rate constant of β-glucuronidase induction
6. Evolution of β-glucuronidase regulation in the genus Mus
7. The use of guanidinium chloride in the isolation of nucleic acids
8. β-Glucuronidase activation of latent aggression-promoting cues in mouse bladder urine
9. Modulation of androgen-responsive gene expression by estrogen
10. The large scale isolation of mouse β-glucuronidase and comparison of allozymes
11. Multiple forms of β-glucuronidase in rat liver lysosomes and microsomes
12. Phenobarbital induction of egasyn: Availability of egasyn in vivo determines glucuronidase binding to membrane
13. Experimental approaches to the study of regulatory evolution
14. Mammalian β-glucuronidase: Genetics, molecular biology, and cell biology
15. Expression of β-glucuronidase haplotypes in prototype and congenic mouse strains
16. Kinetics of β-glucuronidase induction by androgen: Genetic variation in the first order rate constant
17. Genetic variation for enzyme structure and systemic regulation in two new haplotypes of the β-glucuronidase gene of Mus musculus castaneus
18. Biochemical and genetic evidence for a macromolecular β-glucuronidase complex in microsomal membranes
19. Genetic regulation of mammalian glucuronidase
20. Abnormal subcellular distribution of β-glucuronidase in mice with a genetic alteration in enzyme structure
21. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose
22. Genetic variations in kinetic constants that describe β-glucuronidase mRNA induction in androgen-treated mice
23. in RNA synthesis rates in vivo for androgen-inducible sequences in mouse kidney
24. Progressive induction of mRNA synthesis for androgen-responsive genes in mouse kidney
25. Genetic determination of kinetic parameters in β-glucuronidase induction by androgen
26. Properties of rat and mouse β-glucuronidase mRNA and cDNA, including evidence for sequence polymorphism and genetic regulation of mRNA levels
27. Two genetic elements regulate murine β-glucuronidase synthesis following transcript accumulation