Inhibitor-Induced Conformational Change in Cytochrome P-450CAM

Biochemistry

Volumn 32, Issue 17, 1993, Pages 4571-4578

  Raag, Reetta ^a,c   Li, Huiying ^a,d   Jones, B C ^b   Poulos, Thomas L ^a,d  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c Enzon Inc ^*  (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPHOR; CARBONYL DERIVATIVE; CATION; CHLORINE; CYTOCHROME P450; ENZYME INHIBITOR; HEME; PHENYLALANINE; TYROSINE;

ARTICLE; CRYSTAL STRUCTURE; DECHLORINATION; ENANTIOMER; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITOR INTERACTION; ENZYME SUBSTRATE; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CAMPHOR; CAMPHOR 5-MONOOXYGENASE; CHEMISTRY, PHYSICAL; CYTOCHROME P-450 ENZYME SYSTEM; IMIDAZOLES; MIXED FUNCTION OXYGENASES; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; STEREOISOMERISM; SUPPORT, U.S. GOV'T, P.H.S.; TEMPERATURE; X-RAY DIFFRACTION;

DRYOBALANOPS;

EID: 0027258737     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00068a013     Document Type: Article

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