5′-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers

Journal of Clinical Investigation

Volumn 91, Issue 5, 1993, Pages 2320-2325

  Madara, James L ^a   Patapoff, Thomas W ^b   Gillece Castro, Beth ^b   Colgan, Sean P ^a   Parkos, Charles A ^a   Delp, Charlene ^a   Mrsny, Randall J ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b GENENTECH INC   (United States)

Author keywords

Adenosine; Electrolyte transport; Inflammation; Leukocyte

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CHLORIDE ION;

ARTICLE; CHLORIDE TRANSPORT; CONTROLLED STUDY; DIARRHEA; ELECTROLYTE TRANSPORT; ENTERITIS; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; INTESTINE SECRETION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADENINE NUCLEOTIDES; ADENOSINE MONOPHOSPHATE; CHLORIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLONIC NEOPLASMS; CULTURE MEDIA, CONDITIONED; EPITHELIUM; HUMAN; INTESTINES; KINETICS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MODELS, BIOLOGICAL; NEUTROPHILS; RIBONUCLEOTIDES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0027258364     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116462     Document Type: Article

References (16)

1. Halm, D. R., and R. A. Frizzell. 1990. Intestinal chloride secretion. In Textbook of Secretory Diarrhea. E. Lebentahl, editor. Raven Press. Ltd., New York. 47-58.
2. Welsh, M. J., P. L. Smith, M. Fromm, and R. A. Frizzell. 1982. Crypts are the site of intestinal fluid and electrolyte secretion. Science (Wash. DC). 218:1219-1221.
3. Kumar, N. B., T. T. Nostrant, and H. D. Appleman. 1982. The histologic spectrum of acute self-limited colitis. Am. J. Surg. Pathol. 6:523-529.
4. Dharmsathaphorn, K., J. A. McRoberts, K. G. Mandel, L. D. Tisdale, and H. Masui. 1984. A human colonic tumor cell line that maintains vectoral transport. Am. J Physiol. 246:G204-G208.
5. Nash, S., C. Parkos, A. Nusrat, C. Delp, and J. L. Madara. 1991. In vitro model of intestinal crypt abscess. J. Clin. Invest. 87:1474-1477.
6. Madara, J. L., C. A. Parkos, S. Nash, J. B. Matthews, C. Delp, and W. Lencer. 1992. Cl secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue. J. Clin. Invest. 89:1938-1944.
7. Colgan, S. P., J. B. Matthews, C. A. Parkos, C. Delp, C. S. Awtrey, and J. L. Madara. 1992. The myeloid leukemia cell line HL-60 produces a factor that induces chloride secretion in cultured epithelial cells. J. Leukocyte Biol. 52:183-187.
8. Karayalcin, S. S., C. W. Sturbaum, J. T. Wachsman, J. H. Cha, and D. W. Powell. 1990. Hydrogen peroxide stimulates rat colonie prostaglandin production and alters electrolyte transport. J. Clin. Invest. 86:60-68.
9. Tamai, H., J. F. Kachur, D. A. Baron, M. D. Grisham, and T. S. Gaginella. 1990. Monochloramine, a neutrophil-derived oxidant stimulates rat colonic secretion. J. Pharmacol. Exp. Ther. 257:884-894.
10. Tamai, H., T. S. Gaginella, J. F. Kachar, M. W. Musch, and E. B. Chang, 1992. Ca-mediated stimulation of C1 secretion by reactive oxygen metabolites in human colonic T84 cells. J. Clin. Invest. 89:301-307.
11. Parkos, C. A., C. Delp, M. A. Arnaout, and J. L. Madara. 1991. Neutrophil migration across a cultured intestinal epithelium: dependence on a CD11b/CD-18-mediated event and enhanced efficiency in the physiological direction. J. Clin. Invest. 88:1605-1612.
12. Mrsny, R. J., J. J. Volwerk, and O. H. Griffith. 1986. A simplified procedure for lipid phosphorus analysis shows that digestion rates vary with phospholipid structure. Chem. Phys. Lipids. 39:185-191.
13. Fenn, J. B., M. Mann, C. K. Meng, S. F. Wong, and C. M. Whitehouse. 1990. Mass spectroscopy. Mass Spectroscopy 9:37-70.
14. 13a. Abraham, E. H., A. G. Prat, L. Gerweck, T. Seneveratne, R. J. Arceci, R. Kramer, G. Guidotti, and H. F. Cantiello. 1993. The multidrug resistance (mdr1) gene product functions as an ATP channel. Proc. Natl. Acad. Sci. USA. 90:312-316.
15. Misumi, Y., O. Shigenori, S. Hirose, and Y. Ikehara. 1990. Primary structure of rat liver 5′-nucleotidase deduced from the cDNA. J. Biol. Chem. 265:2178-2183.
16. Thompson, L. F., J. M. Ruedi, A. Glass, G. Moldenhauser, P. Moller, M. G. Low, M. R. Klemens, M. Massaia, and A. H. Lucas. 1990. Production and characterization of monoclonal antibodies to the glycosyl phophatidylinositol-anchored lymphocyte differentiation antigen ecto-5′-nucleotidase (CD73). Tissue Antigens. 35:9-19.