Immunoglobulin heavy chain variable region polymorphisms and multiple sclerosis susceptibility

Journal of Neuroimmunology

Volumn 44, Issue 1, 1993, Pages 77-83

  Hashimoto, L L ^a   Walter, M A ^b   Cox, D W ^c   Ebers, G C ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Haplotype sharing; Immunoglobulin heavy chain variable region; Multiple sclerosis; VH2 5

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; TWINS;

ALLELES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; MULTIPLE SCLEROSIS; POLYMORPHISM (GENETICS); SUPPORT, NON-U.S. GOV'T;

EID: 0027252104     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-5728(93)90270-9     Document Type: Article

References (35)

1. The germline repertoire of T cell receptor beta chain genes in patients with chronic progressive multiple sclerosis
2. Content and organization of the human Ig VH locus: definition of three new VH families and linage to the Ig CH locus
3. A comparison of sib pair tests for disease susceptibility loci
4. DNA length polymorphism 5′ to the myelin basic protein gene is associated with multiple sclerosis
5. Allele frequencies of the third component of complement (C3) in MS patients
6. Genomic sequencing
7. HLA in genetic susceptibility of MS: A recessive effect and the role of other genes
8. Oligoclonal banding in MS
9. The genetics of multiple sclerosis
10. HLA typing in multiple sclerosis sibling pairs
11. A population-based study of multiple sclerosis in twins
12. Oligoconal bands in multiple sclerosis: Clinical-pathologic correlation
13. Interaction between T cell receptor beta chain and immunoglobulin heavy chain region genes in susceptibility to insulin-dependent diabetes mellitus
14. The germline repertoire of T-cell receptor β chain genes in patients with relapsing/remitting multiple sclerosis of optic neuritis
15. Epidemiology of multiple sclerosis in London and Middlesex Coundy, Ontario, Canada
16. Genetic susceptibility to multiple sclerosis: a review
17. No association with germline T cell receptor β-chain gene alleles or haplotypes in Swedish patients with multiple sclerosis
18. C3 polymorphisms and circulating immune complexes in patients with multiple sclerosis
19. Introduction to sample size determination and power analysis for clinical trials
20. Principles of albumin and IgG analyses in neurological diseases. II. Evaluation of IgG synthesis within the CNS in MS
21. Multiple sclerosis: epidemiology and HLA associations
22. T cell receptor V alpha and C alpha alleles associated with multiple sclerosis and myasthenia gravis
23. Immunoglobulin G heavy chain (Gm) allotypes in multiple sclerosis
24. New diagnostic criteria for multiple sclerosis. Guidelines for research protocols
25. The familial nature of multiple sclerosis: Age corrected empiric risks for children and siblings of patients
26. Multiple sclerosis: updated risks
27. Association of CSF immunoglobulin G concentrations and immunoglobulin allotype in multiple sclerosis and optic neuritis
28. A susceptibility locus for multiple sclerosis is linked to the T cell receptor beta chain complex
29. Analysis of genetic variation reveals human immunoglobulin variable heavy region gene organization
30. The physical organization of the human immunoglobulin heavy chain gene complex
31. Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region
32. The natural history of multiple sclerosis: A geographically based study. I. Clinical course and disability
33. A comparison of sporadic and familial multiple sclerosis
34. A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, Minnesota