Verapamil and aspirin modulate platelet-mediated vasomotion in arterial segments with intact or disrupted endothelium

Journal of the American College of Cardiology

Volumn 22, Issue 3, 1993, Pages 684-689

  Raymenants, Erwin ^a   Yang, Baichun ^a   Nicolini, Francesca ^a   Behrens, Phillip ^a   Lawson, Daniel ^a   Mehta, Jawahar L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ACETYLCHOLINE; ACETYLSALICYLIC ACID; ENDOTHELIUM DERIVED RELAXING FACTOR; GLYCERYL TRINITRATE; NORADRENALIN; SEROTONIN; VERAPAMIL;

ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; ENDOTHELIUM; HUMAN; HUMAN CELL; NONHUMAN; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; THROMBOCYTE AGGREGATION;

ANIMAL; AORTA; ASPIRIN; BLOOD PLATELETS; CELL SEPARATION; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HUMAN; IN VITRO; PLATELET AGGREGATION; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; VASCULAR RESISTANCE; VERAPAMIL;

EID: 0027248555     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0735-1097(93)90177-3     Document Type: Article

References (32)

1. Inhibitory role of the endothelium in the response of isolated coronary arteries to platelets
2. 2, and adenine nucleotides
3. Platelets, endothelium, and vasospasm
4. Specific platelet mediators and unstable coronary artery lesions: experimental evidence and potential clinical implications
5. Endothelial, platelet and leukocyte interactions in ischemic heart disease: insights into potential mechanisms and their clinical relevance
6. Inhibition of human platelet functions by verapamil
7. Effects of verapamil on platelet aggregation, ATP release and thromboxane formation
8. Arachidonic acid metabolites and the interaction between platelets and blood vessel wall
9. 4 potentiates the contractile effects of epinephrine and norepinephrine on rat aortic rings
10. Modulation of vascular tone by endothelin-1: role of preload, endothelial integrity and concentration of endothelin-1
11. Slow channel calcium blockers attenuate reoxygenation-mediated vascular contraction, but augment severe hypoxia-mediated vascular contraction
12. Thrombosis in unstable angina: pathologic aspects
13. Severe intracoronary thromboxane release preceding acute coronary occlusion
14. Platelet activation in unstable coronary disease
15. 2 and other mediators of vasoconstriction
16. 2 aid serotonin are possible mediators
17. 2 antagonist ritanserin
18. Pharmacokinetics of verapamil and norverapamil during long-term oral therapy
19. Pharmacokinetics of verapamil in patients with hypertension
20. ++ antagonist lidoflazine on normoxic and anoxic contractions of canine coronary arterial smooth muscle
21. Release of nitrogen oxides from cultured bovine aortic endothelial cells is not impaired by calcium channel antagonists
22. Calcium and endothelium-mediated vascular smooth muscle relaxation in rabbit aorta
23. Vasoconstrictor effect of endothelin on the canine coronary artery: is a novel endegenous peptide involved in regulating myocardial blood flow and coronary spasm?
24. Platelets enhance anoxic contraction of rat aortic rings via PAF-dependent mechanism
25. Autologous platelets increase the tone of quiescent rat aortic rings by release of serotonin and potentiate the subsequent contractile response to norepinephrine
26. Aspirin in myocardial ischemia: why, when and how much?
27. Platelet activation by a synthetic hydrophobic polymer polymethylmethacrylate
28. Interaction between nitroglycerin and endothelium in vascular smooth muscle relaxation
29. Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo
30. Secondary prevention of vascular disease by prolonged antiplatelet treatment
31. Verapamil therapy for unstable angina pectoris: review of double-blind placebo-controlled randomized clinical trials
32. Treatment with verapamil during and after an acute myocardial infarction a review based on the Danish Verapamil Infarction Trials I and II