Vasodilation to acetylcholine in primary and secondary forms of human hypertension

Hypertension

Volumn 21, Issue 6, 1993, Pages 929-933

  Taddei, Stefano ^a   Virdis, Agostino ^a   Mattei, Paola ^a   Salvetti, Antonio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Acetylcholine; Endothelium; Essential; Hyperaldosteronism; Hypertension; Indomethacin; Nitroprusside; Prostagiandin endoperoxide synthase; Renovascular

Indexed keywords

ACETYLCHOLINE; INDOMETACIN; NITROPRUSSIDE SODIUM; PROSTAGLANDIN SYNTHASE;

ADULT; BLOOD PRESSURE REGULATION; BLOOD VESSEL TONE; CLINICAL ARTICLE; CONFERENCE PAPER; DRUG EFFECT; ESSENTIAL HYPERTENSION; FEMALE; FOREARM BLOOD FLOW; HUMAN; MALE; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; RENOVASCULAR HYPERTENSION; VASCULAR ENDOTHELIUM; VASODILATATION;

ACETYLCHOLINE; BLOOD VESSELS; FEMALE; FOREARM; HUMAN; HYPERALDOSTERONISM; HYPERTENSION; HYPERTENSION, RENOVASCULAR; INDOMETHACIN; MALE; MIDDLE AGE; NITROPRUSSIDE; VASODILATION;

EID: 0027245468     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.21.6.929     Document Type: Article

References (24)

1. Luscher TF, Vanhoutte PM: The Endothelium: Modulator of Car-diovasadar Function. Boca Raton, Fla, CRC Press, 1990
2. Konishi M, Su C: Role of endothelium in dilator responses of spontaneously hypertensive rat arteries. Hypertension 1983;5; 881-886
3. Winquisl RJ, Bunting RB, Baskin EP, Wallace AA: Decreased endothelium-dependent relaxation in New Zealand genetic hypertensive rats. J Hypertens 1984;2:536-541
4. Luscher TF, Vanhoutte PM: Endothelium-dependent contractions to acetylcholine in the aorta of spontaneously hypertensive rats. Hyper tension 1986;8:344-348.
5. Locketle WE, Otsua Y, Carretero OA: Endothelium-dependent relaxation in hypertension. Hypertension 1986;8(suppl II): II-61-II-66
6. Van de Voorde J, Leusen I; Endothelium-dependent and independent relaxation of aortic rings from hypertensive rats. Am J Physiol1986;250:H711-H717
7. Aalkjaer C, Heagerty AM, Swales JD, Thurston H: Endothelium- dependent relaxation in human subcutaneous resistance vessels. Blood Vessels 1987;24:85-88
8. Diederich D, Yang Z, Buhler FR, Luscher TF: Impaired endothelium-dependent relaxations in hypertensive resistance arteries involve the cyclooxygenase pathway. Am J Physiol 1990;258: H445-H451
9. Furchgott RF, Zawadzky JV; The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373-376
10. Linder L, Kiowski W, Buhler FR, Luscher TF: Indirect evidence for the release of endothelium-derived relaxing factor in the human forearm circulation in vivo: Blunted response in essential hypertension. Circulation 1990;81:1762-1767
11. Panza JA, Quyyumi AA, Brush JE Jr, Epstein SE: Abnormal endothelium dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990;323:22-27
12. Pedrinelli R, Taddei S, Graziadei L, Salvetti A: Vascular responses to ouabain and norepinephrine in low and normal renin hypertension, Hypertension 1986;8:786-792
13. Whitney RJ: The measurement of volume changes in human limbs. J Physiol (Lond) 1953;121:1-27
14. Moncada S, Vane JR: Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane Ai and prostacyclin, Pharmacol Rev 1979;30:293-331
15. Schultz KD, Schultz K, Schultz G: Sodium nitroprusside and other smooth muscle relaxants increase cyclic GMP levels in rat ductus deferens. Nature 1977;265:750-751
16. VaUance P, Coller J, Moncada S: Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man. Lancet 1989;2: 997-1000
17. Kiowski W: Endothelial function in humans: Studies of forearm resistance vessels. Hypertension 1991;18(suppl II): II-84-11-89
18. Folkow B; Physiological aspects of primary hypertension. Physiol Rev 1982;62:347-504
19. Luscher TF, Vanhoutte PM, Raij L: Anti hypertensive therapy normalizes endothelium-dependent relaxations in salt-induced hypertension of the rat. Hypertension 1987;9(suppl 11):I11-193-11I-197
20. Raij L, Luscher TF, Vanhoutte PM: High potassium diet augments endothelium-depen dent relaxations in the Dahl rat. Hypertension1988;12:562-567
21. Dohi Y, Criscione L, Luscher TF: Renovascular hypertension impairs formation of endothelium-derived relaxing factors and sensitivity to endothelin-1 in resistance arteries. BrJ Pharmacol 1991; 104:349-354
22. Tesfamariam B, Halpen W: Endothelium-dependent and endothelium-independent vasodilation in resistance arteries from hypertensive rats. Hypertension 1988;11:440-444
23. Auch-Schwelk W, Katusic ZS, Vanhoutte PM: Contractions to oxygen-derived free radicals are augmented in the aorta of the spontaneously hypertensive rat, Hypertemion 1989;13:859-864
24. Nakamura T, Prewitt RL: Effect of N°-mo no methyl-Largi nine on endothelium-dependent relaxation in arterioles of one-kidney, one dip hypertensive rats. Hypertension 1991;17:875-880