A survey on quantitative microdialysis: theoretical models and practical implications

Journal of Neuroscience Methods

Volumn 48, Issue 3, 1993, Pages 251-261

  Kehr, Jan ^a  

^a CMA / Microdialysis AB ^*  (Sweden)

Author keywords

Brain; Convective diffusion; Drug concentration; Extracellular fluid; Neurotransmitter release; Pharmacokinetics; Quantitative microdialysis

Indexed keywords

DRUG; THEOPHYLLINE; ZIDOVUDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BRAIN REGION; MICRODIALYSIS; NEUROTRANSMITTER RELEASE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; REVIEW;

ANIMAL; BRAIN CHEMISTRY; DIALYSIS; HUMAN; MICROCHEMISTRY; MODELS, THEORETICAL; NEUROTRANSMITTERS;

EID: 0027244155     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-0270(93)90096-A     Document Type: Review

References (52)

1. Flow dependent changes in the effective surface area of microdialysis probes
2. Intracerebral microdialysis. II. Mathematical studies of diffusion kinetics
3. Microdialysis: theory and application
4. Determination of brain interstitial concentrations by microdialysis
5. Practical aspects of using microdialysis for determination of brain interstitial concentrations
6. The concentrations of free amino acids and other electrolytes in cerebrospinal fluid, in vivo dialysate of brain, and blood plasma of the dog
7. Microdialysis of subcutaneous adipose tissue in vivo for continuous glucose monitoring in man
8. Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro
9. Comparison of mathematical models of microdialysis
10. Continuous monitoring of extracellular lactate concentration by microdialysis lactography for the study of rat muscle metabolism in vivo
11. Muscle microdialysis as a model study to relate the drug concentration in tissue interstitial fluid and dialysate
12. Use of quantitative autoradiography to interpret effects of solute metabolism and microvascular exchange on tissue concentration profiles due to microdialysis
13. Quantitative examination of tissue concentration profiles associated with microdialysis
14. Estimation of unbound concentrations of morphine from microdialysate concentrations by use of nonlinear regression analysis in vivo and in vitro during steady state conditions
15. Can in vivo recovery be determined by mannitol?
16. The use of microdialysis for the in vivo study of skeletal muscle glucose metabolism
17. Neuronal dependence of extracellular dopamine, acetylcholine, glutamate, aspartate and gamma-aminobutyric acid (GABA) measured simultaneously from rat neostriatum using in vivo microdialysis: reciprocal interactions
18. Ethanol may be used with the microdialysis technique to monitor blood flow changes in skeletal muscle: dialyste glucose concentration is blood flow dependent
19. Effects of different semipermeable membranes on in vitro and in vivo performance of microdialysis probes
20. Mass transfer in brain dialysis devices: a new method for estimation of extracellular amino acids concentraton
21. Evidence for lactate production by human adipose tissue in vivo
22. Interstitial glycerol concentration measured by microdialysis in two subsutaneous regions in humans
23. Changes in cerebral blood flow do not directly affect in vivo recovery of extracellular lactate through microdialysis probe
24. The use of an “internal standard” for control of the recovery in microdialysis
25. In vivo determination of extracellular concentration of amino acids in the rat hippocampus
26. Intracerebral microdialysis. I. Experimental studies of diffusion kinetics
27. Monte Carlo stimulation of extracellular diffusion in brain tissues
28. A microdialysis method allowing characterization of intercellular water space in humans.
29. Microdialysis of intercellular adenosine concentration in subcutaneous tissue in humans.
30. In vivo calibration of microdialysis probes for exogenous compounds
31. Exploring the stop-flow microdialysis technique as a method to estimate the external concentration of neuropeptides
32. Quantitative microdialysis: analysis of transients and application to pharmacokinetics in brain
33. Quantitative microdialysis
34. Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum
35. The migration of substances in the neuronal microenvironment
36. Diffusion from an iontophoretic point source in the brain: role of tortuosity and volume fraction
37. Quantitative microdialysis under transient conditions
38. Extracellular concentrations and in vivo recovery of dopamine in the nucleus accumbens using microdialysis
39. The in vivo microdialysis recovery of dopamine is altered independently of basal level by 6-hydroxydopamine lesions to the nucleus accumbens
40. Diffusion coefficients of neurotransmitters and their metabolites in brain extracellular fluid space
41. The internal reference technique in microdialysis: a practical approach to monitoring dialysis efficiency and to calculating tissue concentration from dialysate samples
42. Quantitative microdialysis of dopamine in the striatum: effect of circadian variation
43. The use of microdialysis in pharmacokinetics and pharmacodynamics
44. Theophylline concentration in the extracellular space of the rat brain: measurement by microdialysis and relation to behaviour
45. A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis
46. Distribution of anti-retroviral effects of thymidine analogues in Macaca fascicularis
47. Determination of invivo steady-state unbound drug concentration in the brain interstitial fluid by microdialysis
48. Dopamine synaptic mechanisms reflected in studies combining behavioural recordings and brain dialysis
49. Analysis of zidovudine distribution to specific regions in rabbit brain using microdialysis
50. Antipyrine as a dialyzable reference to correct differences in efficiency among and within sampling devices during in vivo microdialysis
51. Purine levels in the intact rat brain