Polymorphism of the mouse TNF-i locus: sequence studies of the 3'-untranslated region and first intron

Gene

Volumn 129, Issue 2, 1993, Pages 279-283

  Beutler, Bruce ^a   Brown, Tracy ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

DNA sequencing; lupus; Mus; mutation; Recombinant DNA; tumor necrosis factor

Indexed keywords

OLIGONUCLEOTIDE; TUMOR NECROSIS FACTOR;

ARTICLE; DNA POLYMORPHISM; GENE LOCUS; HAPLOTYPE; INTRON; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESTRICTION SITE;

ANIMAL; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; DNA TRANSPOSABLE ELEMENTS; HAPLOTYPES; INTRONS; MICE; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; MUTATION; POLY A; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; REPRESSOR PROTEINS; RESTRICTION MAPPING; SPECIES SPECIFICITY; SUPPORT, U.S. GOV'T, P.H.S.; TRANSLATION, GENETIC; TUMOR NECROSIS FACTOR;

MUS; MUS MUSCULUS; MUS SPRETUS; MUSCULUS;

EID: 0027236840     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(93)90280-G     Document Type: Article

References (20)

1. TNF-a gene polymorphisms in type l (insulin-dependent) diabetes mellitus
2. Coordinate regulation of TNF biosynthesis at the levels of transcription and translation. Patterns of TNF expression in vivo
3. Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators
4. Some disease-associated ancestral haplotypes carry a polymorphism of TNF
5. Tumor necrosis factor a gene polymorphism in multiple sclerosis and optic neuritis
6. The essential role of the UA-rich sequence in endotoxin-induced cachectin/TNF synthesis
7. Endotoxin-responsive sequences control cachectin/TNF biosynthesis at the translational level
8. Interactive effects of the TNF promoter and 3'-untranslated regions
9. Tumour necrosis factor-α in murine autoimmune ‘lupus’ nephritis
10. Prevention of diabetes in nonobese diabetes mice by tumor necrosis factor (TNF): similarities between TNF-α and interleukin 1
11. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor a: relevance to genetic predisposition to systemic lupus erythematosus
12. A polymorphic microsatellite in the tumor necrosis factor α promoter identifies an allele unique to the NZW mouse strain
13. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model or arthritis
14. Genetic analysis for insulitis in the NOD mouse
15. Polymorphic structure of the tumor necrosis factor (TNF) locus: an Ncol polymorphism in the first intron of the human TNF-β gene correlates with a variant amino acid in position 26 and a reduced level of TNF-β production
16. Low degree of DNA polymorphism in the HLA-linked lymphotoxin (tumour necrosis factor β) gene
17. DNA sequencing with chainterminating inhibitors
18. Recombinant human tumor necrosis factor a suppresses autoimmune diabetes in nonobese diabetic mice
19. Nucleotide sequence of the murine TNF locus, including the TNF-α (tumor necrosis factor) and TNF-β (lymphotoxin) genes