메뉴 건너뛰기




Volumn 67, Issue 6, 1993, Pages 1274-1284

Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN P53;

EID: 0027233830     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.1993.238     Document Type: Article
Times cited : (120)

References (91)
  • 2
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • BAKER, S.J., MARKOVITZ, S., FEARON, E.R., WILLSON, J.K. & VOGELSTEIN, B. (1990). Suppression of human colorectal carcinoma cell growth by wild-type p53. Science, 249, 912-915.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markovitz, S.2    Fearon, E.R.3    Willson, J.K.4    Vogelstein, B.5
  • 3
    • 0022483186 scopus 로고
    • Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression
    • BANKS, L., MATLASHEWSKI, G. & CRAWFORD, L. (1986). Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur. J. Biochem., 259, 529-534.
    • (1986) Eur. J. Biochem , vol.259 , pp. 529-534
    • Banks, L.1    Matlashewski, G.2    Crawford, L.3
  • 4
    • 0025221197 scopus 로고
    • Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro
    • BARTEK, J., BARTKOVA, J., VOJTESEK, B., STADKOVA, Z., REJTHAR, A., KOVARIK, J. & LANE, D.P. (1990a). Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro. Int. J. Cancer, 46, 839-844.
    • (1990) Int. J. Cancer , vol.46 , pp. 839-844
    • Bartek, J.1    Bartkova, J.2    Vojtesek, B.3    Stadkova, Z.4    Rejthar, A.5    Kovarik, J.6    Lane, D.P.7
  • 5
    • 0025367297 scopus 로고
    • Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines
    • BARTEK, J., IGGO, R., GANNON, J. & LANE, D.P. (19906). Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene, 5, 893-899.
    • (1990) Oncogene , vol.5 , pp. 893-899
    • Bartek, J.1    Iggo, R.2    Gannon, J.3    Lane, D.P.4
  • 7
    • 0026086788 scopus 로고
    • Tumorigenic transformation of spontaneously immortalized fibroblasts from patients with a familial cancer syndrome
    • BISCHOFF, F.Z., STRONG, L.C., YIM, S O., PRATT, D R., SICILIANO, M.J., GIOVANELLA, B.C. & TAINSKY, M.A. (1991). Tumorigenic transformation of spontaneously immortalized fibroblasts from patients with a familial cancer syndrome. Oncogene, 6, 183-186.
    • (1991) Oncogene , vol.6 , pp. 183-186
    • Bischoff, F.Z.1    Strong, L.C.2    Yim, S.O.3    Pratt, D.R.4    Siciliano, M.J.5    Giovanella, B.C.6    Tainsky, M.A.7
  • 8
    • 0025650332 scopus 로고
    • Spontaneous abnormalities in normal fibroblasts from patients with li-fraumeni cancer syndrome: Aneuploidy and immortalization
    • BISCHOFF, F.Z., YIM, S O., PATHAK, S., GRANT, G., SICILIANO, M.J., GIOVANELLA, B.C., STRONG, L.C. & TAINSKY, M.A. (1990). Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization. Cancer Res., 50, 7979-7984.
    • (1990) Cancer Res , vol.50 , pp. 7979-7984
    • Bischoff, F.Z.1    Yim, S.O.2    Pathak, S.3    Grant, G.4    Siciliano, M.J.5    Giovanella, B.C.6    Strong, L.C.7    Tainsky, M.A.8
  • 11
    • 0026579237 scopus 로고
    • Tp53 tumor suppressor gene - a model for investigating human mutagenesis
    • CARON DE FROMENTEL, C. & SOUSSI, T. (1992). TP53 Tumor suppressor gene - a model for investigating human mutagenesis. Genes Chromosomes & Cancer, 4, 1-15.
    • (1992) Genes Chromosomes & Cancer , vol.4 , pp. 1-15
    • Caron De Fromentel, C.1    Soussi, T.2
  • 12
    • 0026054909 scopus 로고
    • Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene
    • CASEY, G., LU-HSUEH, M., LOPEZ, M.E., VOGELSTEIN, B. & STANBRIDGE, E.J. (1991). Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene. Oncogene, 6, 1791-1797.
    • (1991) Oncogene , vol.6 , pp. 1791-1797
    • Casey, G.1    Lu-Hsueh, M.2    Lopez, M.E.3    Vogelstein, B.4    Stanbridge, E.J.5
  • 14
    • 0025611503 scopus 로고
    • Genetic mechanisms of tumor suppression by the human p53 gene
    • CHEN, P.L., CHEN, Y., BOOKSTEIN, R. & LEE, W.H. (1990). Genetic mechanisms of tumor suppression by the human p53 gene. Science, 250, 1576-1580.
    • (1990) Science , vol.250 , pp. 1576-1580
    • Chen, P.L.1    Chen, Y.2    Bookstein, R.3    Lee, W.H.4
  • 15
    • 0025934732 scopus 로고
    • Expression of wild-type p53 in human a673 cells suppresses tumorigenicity but not growth rate
    • CHEN, Y., CHEN, P.L., ARNAIZ, N., GOODRICH, D. & LEE, W.H. (1990). Expression of wild-type p53 in human A673 cells suppresses tumorigenicity but not growth rate. Oncogene, 6, 1799-1805.
    • (1990) Oncogene , vol.6 , pp. 1799-1805
    • Chen, Y.1    Chen, P.L.2    Arnaiz, N.3    Goodrich, D.4    Lee, W.H.5
  • 16
    • 0026572023 scopus 로고
    • Suppression of acute lymphoblastic leukemia by the human wild-type p53 gene
    • CHENG, J., YEE, J.K., YEARGIN, J., FRIEDMANN, T. & HASS, M. (1991). Suppression of acute lymphoblastic leukemia by the human wild-type p53 gene. Cancer Res., 52, 222-226.
    • (1991) Cancer Res , vol.52 , pp. 222-226
    • Cheng, J.1    Yee, J.K.2    Yeargin, J.3    Friedmann, T.4    Hass, M.5
  • 18
    • 0025988293 scopus 로고
    • Degradation of p53 can be targeted by hpv e6 sequences distinct from those required for p53 binding and transactivation
    • CROOK, T., TIDY, J.A. & VOUSDEN, K.H. (1991a). Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and transactivation. Cell, 67, 547-556.
    • (1991) Cell , vol.67 , pp. 547-556
    • Crook, T.1    Tidy, J.A.2    Vousden, K.H.3
  • 19
    • 0025896299 scopus 로고
    • Status of c-myc, p53 and retinoblastoma genes in human papillomavirus positive and negative squamous cell carcinomas of the anus
    • CROOK, T., WREDE, D., TIDY, J., SCHOLEFIELD, J., CRAWFORD, L. & VOUSDEN, K.H. (1991a). Status of c-myc, p53 and retinoblastoma genes in human papillomavirus positive and negative squamous cell carcinomas of the anus. Oncogene, 6, 1251-1257.
    • (1991) Oncogene , vol.6 , pp. 1251-1257
    • Crook, T.1    Wrede, D.2    Tidy, J.3    Scholefield, J.4    Crawford, L.5    Vousden, K.H.6
  • 22
    • 0019499955 scopus 로고
    • Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck
    • EASTY, DM., EASTY, G.C., CARTER, R.L., MONOGHAN, P. & BUTLER, L.J. (1981). Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck. Br. J. Cancer, 43, 772-785.
    • (1981) Br. J. Cancer , vol.43 , pp. 772-785
    • Easty, D.M.1    Easty, G.C.2    Carter, R.L.3    Monoghan, P.4    Butler, L.J.5
  • 23
    • 0023261211 scopus 로고
    • Clonal analysis of human colorectal tumours
    • FEARON, E.R., HAMILTON, S.R. & VOGELSTEIN, B. (1987). Clonal analysis of human colorectal tumours. Science, 238, 193-197.
    • (1987) Science , vol.238 , pp. 193-197
    • Fearon, E.R.1    Hamilton, S.R.2    Vogelstein, B.3
  • 24
    • 0025738297 scopus 로고
    • Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck
    • FIELD, J.K., SPANDIDOS, D.A., MALLIRI, A., GOSNEY, J R., YIAGNISIS, M. & STELL, P.M. (1991). Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck. Br. J. Cancer, 64, 573-577.
    • (1991) Br. J. Cancer , vol.64 , pp. 573-577
    • Field, J.K.1    Spandidos, D.A.2    Malliri, A.3    Gosney, J.R.4    Yiagnisis, N.5
  • 25
    • 0024382760 scopus 로고
    • The p53 protooncogene can act as a suppressor of transformation
    • FINLAY, C.A., HINDS, P.W. & LEVINE, A.J. (1989). The p53 protooncogene can act as a suppressor of transformation. Cell, 57, 1083-1093.
    • (1989) Cell , vol.57 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 26
    • 0023959795 scopus 로고
    • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
    • FINLAY, C.A., HINDS, P.W., TAN, T.H., ELIYAHU, D., OREN, M. & LEVINE, A.J. (1988). Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol. Cell. Biol., 8, 531-539.
    • (1988) Mol. Cell. Biol , vol.8 , pp. 531-539
    • Finlay, C.A.1    Hinds, P.W.2    Tan, T.H.3    Eliyahu, D.4    Oren, M.5    Levine, A.J.6
  • 28
    • 0018033879 scopus 로고
    • Cyclic amp in relation to proliferation of the epidermal cell: A new view
    • GREEN, H. (1978). Cyclic AMP in relation to proliferation of the epidermal cell: a new view. Cell, 15, 801-811.
    • (1978) Cell , vol.15 , pp. 801-811
    • Green, H.1
  • 30
    • 0025085667 scopus 로고
    • Different tumor-derived p53 mutants exhibit distinct biological activities
    • HALEVY, O., MICHAELOVITZ, D. & OREN, M. (1990). Different tumor-derived p53 mutants exhibit distinct biological activities. Science, 250, 113-116.
    • (1990) Science , vol.250 , pp. 113-116
    • Halevy, O.1    Michaelovitz, D.2    Oren, M.3
  • 31
    • 0026303190 scopus 로고
    • P53 alteration is a common event in the spontaneous immortalisation of primary balb. C murine embryo fibroblasts
    • HARVEY, D.M. & LEVINE, A.J. (1991). p53 alteration is a common event in the spontaneous immortalisation of primary BALB. C murine embryo fibroblasts. Genes & Development, 5, 2375-2385.
    • (1991) Genes & Development , vol.5 , pp. 2375-2385
    • Harvey, D.M.1    Levine, A.J.2
  • 32
    • 0024804363 scopus 로고
    • Hpv16 e6 and e7 proteins cooperate to immortalize human foreskin keratinocytes
    • HAWLEY-NELSON, P., VOUSDEN, K.H., HUBBERT, N.L., LOWY, D R. & SCHILLER, J.T. (1989). HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes. EMBO J., 8., 3905-3910.
    • (1989) EMBO J , vol.8 , pp. 3905-3910
    • Hawley-Nelson, P.1    Vousden, K.H.2    Hubbert, N.L.3    Lowy, D.R.4    Schiller, J.T.5
  • 35
    • 0026074818 scopus 로고
    • Cooperation between oncogenes
    • HUNTER, T. (1991). Cooperation between oncogenes. Cell, 64, 249-270.
    • (1991) Cell , vol.64 , pp. 249-270
    • Hunter, T.1
  • 37
    • 0003498375 scopus 로고
    • Monographs on the evaluation of the carcinogenic risk of chemicals to humans
    • IARC Lyon
    • IARC (1986). Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Vol. 38, Tobacco Smoking IARC Lyon.
    • (1986) Tobacco Smoking , vol.38
  • 38
    • 0025265724 scopus 로고
    • Increased expression of mutant forms of p53 oncogene in primary lung cancer
    • IGGO, R., GATTER, K., BARTER, J., LANE, D. & HARRIS, A.L. (1990). Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet, 335, 675-679.
    • (1990) Lancet , vol.335 , pp. 675-679
    • Iggo, R.1    Gatter, K.2    Barter, J.3    Lane, D.4    Harris, A.L.5
  • 39
    • 0026047990 scopus 로고
    • From gene to carcinogen: A rapidly evolving field in molecular epidemiology
    • JONES, P.A., BUCKLEY, J.D., HENDERSON, B E., ROSS, R.K. & PIKE, M.C. (1991). From gene to carcinogen: a rapidly evolving field in molecular epidemiology. Cancer Res., 51, 3617-3620.
    • (1991) Cancer Res , vol.51 , pp. 3617-3620
    • Jones, P.A.1    Buckley, J.D.2    Henderson, B.E.3    Ross, R.K.4    Pike, M.C.5
  • 40
    • 0026488680 scopus 로고
    • Mutations in the p53 gene in radiation-sensitive and -resistant human squamous carcinoma cells
    • JUNG, M., NOTARIO, V. & DRITSCHILO, A. (1992). Mutations in the p53 gene in radiation-sensitive and -resistant human squamous carcinoma cells. Cancer Res., 52, 6390-6393.
    • (1992) Cancer Res , vol.52 , pp. 6390-6393
    • Jung, M.1    Notario, V.2    Dritschilo, A.3
  • 41
    • 0023890291 scopus 로고
    • Characterization of primary keratinocytes transformed by human papillomavirus type 18
    • KAUR, P. & MCDOUGALL, J.K. (1988). Characterization of primary keratinocytes transformed by human papillomavirus type 18. J. Virol., 62, 1917-1924.
    • (1988) J. Virol , vol.62 , pp. 1917-1924
    • Kaur, P.1    McDougall, J.K.2
  • 42
    • 0018348655 scopus 로고
    • T antigen is bound to a host protein in sv40 transformed cells
    • LANE, D.P. & CRAWFORD, L.V. (1979). T antigen is bound to a host protein in SV40 transformed cells. Nature, 278, 261-263.
    • (1979) Nature , vol.278 , pp. 261-263
    • Lane, D.P.1    Crawford, L.V.2
  • 43
    • 0026317634 scopus 로고
    • A germ line mutation in exon 5 of the p53 gene in an extended cancer family
    • LAW, J.C., STRONG, L.C., CHIDAMBARAM, A. & FERRELI, R E. (1991). A germ line mutation in exon 5 of the p53 gene in an extended cancer family. Cancer Res., 51, 6385-6387.
    • (1991) Cancer Res , vol.51 , pp. 6385-6387
    • Law, J.C.1    Strong, L.C.2    Chidambaram, A.3    Ferreli, R.E.4
  • 44
    • 0014654544 scopus 로고
    • Rhabdomyosarcoma in children: Epidemiologic study and identification of a familial cancer syndrome
    • LI, F.P. & FRAUMENI, J.F. Jr. (1969). Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome. J. Natl Cancer Inst., 43, 1365-1373.
    • (1969) J. Natl Cancer Inst , vol.43 , pp. 1365-1373
    • Li, F.P.1    Fraumeni, J.F.2
  • 45
    • 0018760324 scopus 로고
    • Characterization of a 54k dalton cellular sv40 tumor antigen present in sv40-transformed cells and uninfected embryonal carcinoma cells
    • LINZER, D.I. & LEVINE, A.J. (1979). Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell, 17, 43-52.
    • (1979) Cell , vol.17 , pp. 43-52
    • Linzer, D.I.1    Levine, A.J.2
  • 46
    • 0021847645 scopus 로고
    • Analysis of oral papillomas, leukoplakias and invasive carcinomas for human papillomavirus type related dna
    • LONING, T., IKENBERG, H., BECKER, J., GISSMAN, L., HOEPFNER, I. & ZUR HAUSEN, H. (1985). Analysis of oral papillomas, leukoplakias and invasive carcinomas for human papillomavirus type related DNA. J. Invest. Dermatol., 88, 417-420.
    • (1985) J. Invest. Dermatol , vol.88 , pp. 417-420
    • Loning, T.1    Ikenberg, H.2    Becker, J.3    Gissman, L.4    Hoepfner, I.5    Zur Hausen, H.6
  • 47
    • 0026636158 scopus 로고
    • Ras-induced hyperplasia occurs with mutation of p53 but activated ras and myc together can induce carcinoma without p53 mutation
    • LU, X., PARK, S.H., THOMPSON, T. & LANE, D.P. (1992). ras-induced hyperplasia occurs with mutation of p53 but activated ras and myc together can induce carcinoma without p53 mutation. Cell, 70, 153-161.
    • (1992) Cell , vol.70 , pp. 153-161
    • Lu, X.1    Park, S.H.2    Thompson, T.3    Lane, D.P.4
  • 48
    • 0026507159 scopus 로고
    • High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx
    • MAESTRO, R., DOLCETTI, R., GASPAROTTO, C., DOGLIONI, C., PELUCCHI, S., BARZAN, L., GRANDI, E. & BOIOCCHI, M. (1992). High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx. Oncogene, 7, 1159-1166.
    • (1992) Oncogene , vol.7 , pp. 1159-1166
    • Maestro, R.1    Dolcetti, R.2    Gasparotto, C.3    Doglioni, C.4    Pelucchi, S.5    Barzan, L.6    Grandi, E.7    Boiocchi, M.8
  • 49
    • 0023619858 scopus 로고
    • Detection of human papillomavirus dna in biopsies of human oral tissue
    • MAITLAND, N.J., COX, M.F., LYNAS, C., PRIME, S.S. & SCULLY, C. (1987). Detection of human papillomavirus DNA in biopsies of human oral tissue. Br. J. Cancer, 56, 245-250.
    • (1987) Br. J. Cancer , vol.56 , pp. 245-250
    • Maitland, N.J.1    Cox, M.F.2    Lynas, C.3    Prime, S.S.4    Scully, C.5
  • 50
    • 0024399927 scopus 로고
    • Detection of human papillomavirus genes in human oral tissue biopsies and cultures by polymerase chain reaction
    • MAITLAND, N.J., BROMIDGE, T., COX, M.F., CRANE, I.J., PRIME, S.S. & SCULLY, C. (1989). Detection of human papillomavirus genes in human oral tissue biopsies and cultures by polymerase chain reaction. Br. J. Cancer, 59, 698-703.
    • (1989) Br. J. Cancer , vol.59 , pp. 698-703
    • Maitland, N.J.1    Bromidge, T.2    Cox, M.F.3    Crane, I.J.4    Prime, S.S.5    Scully, C.6
  • 53
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • MICHAELOVITZ, D., HALEVY, O. & OREN, M. (1990). Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell, 62, 671-680.
    • (1990) Cell , vol.62 , pp. 671-680
    • Michaelovitz, D.1    Halevy, O.2    Oren, M.3
  • 54
    • 0025731379 scopus 로고
    • Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation
    • MILNER, J. & MEDCALF, E.A. (1991). Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation. Cell, 65, 765-774.
    • (1991) Cell , vol.65 , pp. 765-774
    • Milner, J.1    Medcalf, E.A.2
  • 56
    • 0024428508 scopus 로고
    • The e6 and e7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
    • MUNGER, K., PHELPS, W.C., BUBB, V., HOWLEY, P.M. & SCHEGEL, R. (1989). The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J. Virol., 63, 4417-4421.
    • (1989) J. Virol , vol.63 , pp. 4417-4421
    • Munger, K.1    Phelps, W.C.2    Bubb, V.3    Howley, P.M.4    Schegel, R.5
  • 57
    • 0021776392 scopus 로고
    • Multistep malignant transformation of mammalian cells by carcinogens: Induction of immortality as a key event. in carcinogenesis: A comprehensive survey
    • Barratt, J.C. & Tennant, R.W. (eds.) Raven Press: New York
    • NEWBOLD, R.F. (1985). Multistep malignant transformation of mammalian cells by carcinogens: induction of immortality as a key event. In Carcinogenesis: a Comprehensive Survey Vol. 9 Mammalian Cell Transformation: Mechanisms of Carcinogenesis and Assays for Carcinogens pp. 17-28. Barratt, J.C. & Tennant, R.W. (eds.) Raven Press: New York.
    • (1985) Mammalian Cell Transformation: Mechanisms of Carcinogenesis and Assays for Carcinogens , vol.9 , pp. 17-28
    • Newbold, R.F.1
  • 59
    • 0026740449 scopus 로고
    • Amplification of a gene encoding a p53-associated protein in human sarcomas
    • OLINER, J.D., KINZLER, K.W., MELTZER, P.S., GEORGE, D.L. & VOGELSTEIN, B. (1992). Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature, 358, 80-83.
    • (1992) Nature , vol.358 , pp. 80-83
    • Oliner, J.D.1    Kinzler, K.W.2    Meltzer, P.S.3    George, D.L.4    Vogelstein, B.5
  • 60
    • 0019830333 scopus 로고
    • Post-translational regulation of the 54k cellular antigen in normal and transformed cells
    • OREN, M., MALTZMAN, W. & LEVINE, A.J. (1981). Post-translational regulation of the 54K cellular antigen in normal and transformed cells. Mol. Cell Biol., 1, 101-110.
    • (1981) Mol. Cell Biol , vol.1 , pp. 101-110
    • Oren, M.1    Maltzman, W.2    Levine, A.J.3
  • 61
    • 0025734560 scopus 로고
    • Immortalization of normal human oral keratinocytes with type 16 human papillomavirus
    • PARK, N.H., MIN, B.M., LI, S.L., HUANG, M.Z., CHERICK, H.M. & DONIGER, J. (1991). Immortalization of normal human oral keratinocytes with type 16 human papillomavirus. Carcinogenesis, 12, 1627-1631.
    • (1991) Carcinogenesis , vol.12 , pp. 1627-1631
    • Park, N.H.1    Min, B.M.2    Li, S.L.3    Huang, M.Z.4    Cherick, H.M.5    Doniger, J.6
  • 62
    • 0020517720 scopus 로고
    • A subpopulation of cultured human keratinocytes which is resistant to the induction of terminal differentiation-related changes by phor- bol, 12-myristate, 13-acetate: Evidence for an increase in the resistant population following transformation
    • PARKINSON, E.K., GRABHAM, P. & EMMERSON, A. (1983). A subpopulation of cultured human keratinocytes which is resistant to the induction of terminal differentiation-related changes by phor- bol, 12-myristate, 13-acetate: evidence for an increase in the resistant population following transformation. Carcinogenesis, 4, 857-861.
    • (1983) Carcinogenesis , vol.4 , pp. 857-861
    • Parkinson, E.K.1    Grabham, P.2    Emmerson, A.3
  • 63
    • 0022551135 scopus 로고
    • The radiosensitivity of cultured human and mouse keratinocytes
    • PARKINSON, E.K., HUME, W.J. & POTTEN, C.S. (1986). The radiosensitivity of cultured human and mouse keratinocytes. Int. J. Rad. Biol., 50, 717-726.
    • (1986) Int. J. Rad. Biol , vol.50 , pp. 717-726
    • Parkinson, E.K.1    Hume, W.J.2    Potten, C.S.3
  • 64
    • 0022257422 scopus 로고
    • Human papillomavirus types 16 and 18 sequences in carcinoma cell lines of the cervix
    • PATER, M.M. & PATER, A. (1985). Human papillomavirus types 16 and 18 sequences in carcinoma cell lines of the cervix. Virology, 145, 313-318.
    • (1985) Virology , vol.145 , pp. 313-318
    • Pater, M.M.1    Pater, A.2
  • 65
    • 0026344436 scopus 로고
    • Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas
    • PIERCEALL, W.E., MUKHOPADHYAY, T., GOLDBERG, L.H. & ANANTHASWAMY, H.N. (1991). Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas. Mol. Carcinog., 4, 445-449.
    • (1991) Mol. Carcinog , vol.4 , pp. 445-449
    • Pierceall, W.E.1    Mukhopadhyay, T.2    Goldberg, L.H.3    Ananthaswamy, H.N.4
  • 66
    • 0023152810 scopus 로고
    • Transformation of human fibroblasts and keratinocytes with human papillomasvirus type 16 dna
    • PIRISI, L., YASUMOTO, S., FELLER, M., DONIGER, J. & DIPAULO, J.A. (1987). Transformation of human fibroblasts and keratinocytes with human papillomasvirus type 16 DNA. J. Virol., 61, 1061-1066.
    • (1987) J. Virol , vol.61 , pp. 1061-1066
    • Pirisi, L.1    Yasumoto, S.2    Feller, M.3    Doniger, J.4    Dipaulo, J.A.5
  • 68
    • 0019124443 scopus 로고
    • Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes
    • RHEINWALD, J.G. & BECKETT, M.A. (1980). Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell, 22, 629-632.
    • (1980) Cell , vol.22 , pp. 629-632
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 69
    • 0019471387 scopus 로고
    • Tumourigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas
    • RHEINWALD, J.G. & BECKETT, M.A. (1981). Tumourigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas. Cancer Res., 41, 1657-1663.
    • (1981) Cancer Res , vol.41 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 70
    • 0016729431 scopus 로고
    • Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells
    • RHEINWALD, J.G. & GREEN, H. (1975). Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell, 6, 331-343.
    • (1975) Cell , vol.6 , pp. 331-343
    • Rheinwald, J.G.1    Green, H.2
  • 71
    • 0025145277 scopus 로고
    • 5-methylcytosine as an endogenous mutagen in the human ldl receptor and p53 genes
    • RIDEOUT, W.M., III, COETZEE, G.A., OLUMI, A.F. & JONES, P.A., (1990). 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science, 249, 1288-1290.
    • (1990) Science , vol.249 , pp. 1288-1290
    • Rideout, W.M.1    Coetzee, G.A.2    Olumi, A.F.3    Jones, P.A.4
  • 73
    • 0025761261 scopus 로고
    • Expression from the murine p53 promoter is mediated by factor binding to a downstream helix-loop-helix recognition motif
    • RONEN, D., ROTTER, V. & REISMAN, D. (1991). Expression from the murine p53 promoter is mediated by factor binding to a downstream helix-loop-helix recognition motif. Proc. Natl Acad. Sci. USA, 88, 4128-4132.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 4128-4132
    • Ronen, D.1    Rotter, V.2    Reisman, D.3
  • 74
    • 0026560020 scopus 로고
    • Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor- suppressor genes
    • SAKAI, E. & TSUCHIDA, N. (1992). Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor- suppressor genes. Oncogene, 7, 927-933.
    • (1992) Oncogene , vol.7 , pp. 927-933
    • Sakai, E.1    Tsuchida, N.2
  • 75
    • 0020079972 scopus 로고
    • Adenovirus elb-58kd tumor antigen and sv40 large tumor antigen are physically associated with the same 54 kd cellular protein in mammalian cells
    • SARNOW, P., HO, Y.S., WILLIAMS, J. & LEVINE, A.J. (1982). Adenovirus Elb-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in mammalian cells. Cell, 28, 387-394.
    • (1982) Cell , vol.28 , pp. 387-394
    • Sarnow, P.1    Ho, Y.S.2    Williams, J.3    Levine, A.J.4
  • 76
    • 0025953696 scopus 로고
    • The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
    • SCHEFFNER, M., MUNGER, K., BYRNE, J.C. & HOWLEY, P. M., (1991). The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc. Natl Acad. Sci, USA, 88, 5523-5527.
    • (1991) Proc. Natl Acad. Sci, USA , vol.88 , pp. 5523-5527
    • Scheffner, M.1    Munger, K.2    Byrne, J.C.3    Howley, P.M.4
  • 77
    • 0025639158 scopus 로고
    • The e6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • SCHEFFNER, M., WERNESS, B.A., HUMBREGTSE, J.M., LEVINE, A.J. & HOWLEY, P.M. (1990). The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63, 1129-1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Humbregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 78
    • 0025648762 scopus 로고
    • Germ-line transmission of a mutated p53 gene in a cancer-prone family with li-fraumeni syndrome
    • SRIVASTAVA, S., ZOU, Z.Q., PIROLLO, K., BLATTNER, W.A. & CHANG, E.H. (1990). Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature, 348, 747-749.
    • (1990) Nature , vol.348 , pp. 747-749
    • Srivastava, S.1    Zou, Z.Q.2    Pirollo, K.3    Blattner, W.A.4    Chang, E.H.5
  • 79
    • 0015514589 scopus 로고
    • Smoking and laryngeal cancer
    • STELL, P.M. (1972). Smoking and laryngeal cancer. Lancet, i, 617-618.
    • (1972) Lancet , vol.1 , pp. 617-618
    • Stell, P.M.1
  • 81
    • 0026717314 scopus 로고
    • Immortalization of conditionally transformed chicken cells: Loss of normal p53 expression is an early step that is independent of cell transformation
    • ULRICH, E., BOEHMELT, G., BIRD, A. & BEUG, H. (1992). Immortalization of conditionally transformed chicken cells: loss of normal p53 expression is an early step that is independent of cell transformation. Genes & Develop., 6, 876-887.
    • (1992) Genes & Develop , vol.6 , pp. 876-887
    • Ulrich, E.1    Boehmelt, G.2    Bird, A.3    Beug, H.4
  • 84
    • 0026669469 scopus 로고
    • P53 function and dysfunction
    • VOGELSTEIN, B. & KINZLER, K.W. (1992). p53 function and dysfunction. Cell, 70, 523-526.
    • (1992) Cell , vol.70 , pp. 523-526
    • Vogelstein, B.1    Kinzler, K.W.2
  • 85
    • 0024399684 scopus 로고
    • Oncogene, antioncogenes, and the molecular bases of multistep carcinogenesis
    • WEINBERG, R.A. (1989). Oncogene, antioncogenes, and the molecular bases of multistep carcinogenesis. Cancer Res., 49, 3713-3721.
    • (1989) Cancer Res , vol.49 , pp. 3713-3721
    • Weinberg, R.A.1
  • 86
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 e6 proteins with p53
    • WERNESS, B.A., LEVINE, A.J. & HOWLEY, P.M. (1990). Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science, 248, 76-79.
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 88
    • 0021746318 scopus 로고
    • Reconstitution of p53 expression in a non producer ab-mulv-transformed cell line by transfection of a functional p53 gene
    • WOLF, D., HARRIS, N. & ROTTER, V. (1984). Reconstitution of p53 expression in a non producer Ab-MuLV-transformed cell line by transfection of a functional p53 gene. Cell, 38, 119-126.
    • (1984) Cell , vol.38 , pp. 119-126
    • Wolf, D.1    Harris, N.2    Rotter, V.3
  • 89
    • 0025928522 scopus 로고
    • Human papillomavirus dna in biopsies of oral tissues
    • YEUDALL, W.A. & CAMPO, M.S. (1991). Human papillomavirus DNA in biopsies of oral tissues. J. Gen. Virol., 72, 173-176.
    • (1991) J. Gen. Virol , vol.72 , pp. 173-176
    • Yeudall, W.A.1    Campo, M.S.2
  • 90
    • 0022572014 scopus 로고
    • Alterations of myc, myb, and rasha proto-oncogenes in cancers are frequent and show clinical correlation
    • YOKOTA, J., TSUNETSUGUYOKOTA, Y., BATTIFORA, H., LE FEVRE, C. & CLINE, M.J. (1986). Alterations of myc, myb, and rasHa proto-oncogenes in cancers are frequent and show clinical correlation. Science, 231, 261-265.
    • (1986) Science , vol.231 , pp. 261-265
    • Yokota, J.1    Tsunetsuguyokota, Y.2    Battifora, H.3    Le Fevre, C.4    Cline, M.J.5
  • 91
    • 0345575500 scopus 로고
    • Loss of heterozygosity of chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung
    • YOKOTA, J., WADA, M., SHIMOSATO, Y., TERADA, M. & SUGIMURA, T. (1987). Loss of heterozygosity of chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung. Proc. Natl Acad. Sci. USA, 84, 9252-9256.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 9252-9256
    • Yokota, J.1    Wada, M.2    Shimosato, Y.3    Terada, M.4    Sugimura, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.