Endogenous porphyrin distribution induced by 5-aminolaevulinic acid in the tissue layers of the gastrointestinal tract

Journal of Photochemistry and Photobiology, B: Biology

Volumn 20, Issue 1, 1993, Pages 47-54

  Loh, C S ^a   Vernon, D ^b   MacRobert, A J ^a   Bedwell, J ^a   Bown, S G ^a   Brown, S B ^b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

5 Aminolaevulinic acid; PDT; Protoporphyrin IX fluorescence

Indexed keywords

AMINOLEVULINIC ACID; HEMATOPORPHYRIN DERIVATIVE; PHOTOSENSITIZING AGENT; PORPHYRIN; PROTOPORPHYRIN;

ANIMAL TISSUE; ARTICLE; FLUORESCENCE; GASTROINTESTINAL TRACT; NONHUMAN; RAT; TISSUE DISTRIBUTION;

AMINOLEVULINIC ACID; ANIMAL; DUODENAL NEOPLASMS; FEMALE; FLUOROMETRY; GASTROINTESTINAL SYSTEM; KINETICS; PHOTOCHEMOTHERAPY; PORPHYRINS; RATS; RATS, WISTAR; SUPPORT, NON-U.S. GOV'T; TISSUE DISTRIBUTION;

EID: 0027227627     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/1011-1344(93)80130-2     Document Type: Article

References (19)

1. Photosensitization of malignant tumors
2. The composition of Photofrin II
3. Hematoporphyrin derivative, quantitative uptake in DMH induced murine colo-rectal carcinoma
4. 14C]-hematoporphyrin derivative in malignant and normal tissue
5. Skin photosensitivity: duration and intensity following intravenous hematoporphyrin derivatives, HpD and DHE
6. Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrin
7. Phototoxic damage to sebaceous glands and hair follicles of mice after systemic administration of 5-aminolevulinic acid correlates with localised protoporphyrin IX fluorescence
8. Fluorescence distribution and photodynamic effect of ALA-induced PP IX in the DMH rat colonic tumour model
9. Photodynamic therapy of the normal rat stomach: a comparative study between disulphonated aluminium phthalocyanine and 5-aminolaevulinic acid
10. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience
11. Non-invasive technique for obtaining fluorescence excitation and emission spectra in vivo
12. Oral vs. iv. administration of 5-ALA
13. 5-aminolaevulinic acid stimulation of porphyrin and haemoglobin synthesis by uninduced friend erythroleukaemic cells
14. Sequential morphological changes in N-methyl-N′-nitro-N-nitrosoguanidine carcinogenesis in the glandular stomach of rats
15. Comparison of distribution and photodynamic effects of di- and tetra-sulphonated aluminium phthalocyanines in normal rat colon
16. Distribution and photosensitising efficiency of porphyrins induced by application of exogenous 5-amonolaevulinic acid in mice bearing mammary carcinoma
17. Selective accumulation of endogenously produced porphyrins in a liver metastatis model in rats
18. Haem biosynthesis in human breast cancer-mimetic in vitro studies and more haem enzymic activity levels