-
1
-
-
0026629423
-
Laminin Enhances Binding of Toxoplasma gondii Tachyzoites to J774 Murine Macrophage Cells
-
of special interest, Laminin is involved in the binding of T. gondii to murine macrophages.
-
(1992)
Infect Immun
, vol.60
, pp. 2337-2342
-
-
Furtado1
Slowik2
Kleinman3
Joiner4
-
2
-
-
0026706230
-
Virulent Strains of Toxoplasma gondii Comprise a Single Clonal Lineage
-
of outstanding interest, Virulent strains of T. gondii are genetically homogeneous and appear to originate from a single lineage.
-
(1992)
Nature
, vol.359
, pp. 82-85
-
-
Sibley1
Boothroyd2
-
3
-
-
0026478014
-
Isoenzyme Analysis of 35 Toxoplasma gondii Isolates and the Biological and Epidemiological Implications
-
of outstanding interest, Based on isoenzyme analysis, strains of T. gondii are divided into five distinctive isoenzyme patterns. The relationship between these patterns and biological behavior of the strains is discussed.
-
(1992)
J Parasitol
, vol.78
, pp. 786-794
-
-
Darde1
Bouteille2
Pestre-Alexandre3
-
4
-
-
0027410335
-
Biology of Toxoplasma gondii
-
of special interest, A comprehensive review of different aspects of T. gondii infection.
-
(1993)
AIDS
, vol.7
, pp. 299-316
-
-
Wong1
Remington2
-
7
-
-
0025778101
-
+) T Lymphocytes Prevents Development of Resistance to Toxoplasma gondii in Mice
-
(1991)
Infect Immun
, vol.59
, pp. 1614-1619
-
-
Araujo1
-
8
-
-
0026749880
-
+ T Lymphocytes is Required to Reactivate Chronic Infection with Toxoplasma gondii
-
+ T lymphocytes appear to act in concert to prevent reactivation of chronic T. gondii infection.
-
(1992)
J Immunol
, vol.149
, pp. 175-180
-
-
Gazzinelli1
Xu2
Hieny3
Cheever4
Sher5
-
9
-
-
0026768053
-
Opportunistic Infections and Retrovirus-induced Immunodeficiency: Studies of Acute and Chronic Infections with Toxoplasma gondii in Mice Infected with LP-BM5 Murine Leukemia Viruses
-
+T lymphocytes and production of IFN-γ. Describes an animal model of toxoplasmosis in mice with virus-induced immunodeficiency similar to that observed in AIDS patients.
-
(1992)
Infect Immun
, vol.60
, pp. 4394-4401
-
-
Gazzinelli1
Hartley2
Fredrickson3
Chattopadhyay4
Sher5
Morse6
-
10
-
-
0027316241
-
Toxoplasma gondii: Induction of Toxoplasmmc Encephalitis in Mice with Chronic Infection by Inoculation of a Murine Leukemia Virus Inducing Immunodeficiency
-
of outstanding interest, Description of an animal model of toxoplasmic encephalitis that mimics disease observed in AIDS patients. Focuses on reactivation of latent infection and provides careful histopathological studies.
-
(1993)
Exp Parasitol
, vol.76
, pp. 39-45
-
-
Watanabe1
Suzuki2
Making3
Fujiwara4
-
11
-
-
0026646688
-
+ T Cells but not Inhibition of the Protective Activity of IFN-γ Prevents Cure of Toxoplasmosis Mediated by Drug Therapy in Mice
-
+ T cells are required in order to cure toxoplasmosis with antimicrobial therapy.
-
(1992)
J Immunol
, vol.149
, pp. 3003-3007
-
-
Araujo1
-
16
-
-
0023685070
-
Induction of antigen-specific parasiticidal cytotoxic T cell splenocytes by a major membrane protein (P30) of Toxoplasma gondii.
-
(1988)
J Immunol
, vol.141
, pp. 3600-3605
-
-
Khan1
Smith2
Kasper3
-
17
-
-
0026598802
-
+ T Cells are Cytotoxic Against Toxoplasma gondii-infected Peritoneal Macrophages
-
+ T lymphocytes appear to recognize p30.
-
(1992)
J Immunol
, vol.148
, pp. 1493-1498
-
-
Kasper1
Khan2
Ely3
Buelow4
Boothroyd5
-
21
-
-
0027204623
-
Bone Marrow Macrophages Process Exogenous Toxoplasma gondii Polypeptides for Recognition by Parasite-specific Cytolytic T Lymphocytes
-
+ T lymphocytes.
-
(1993)
J Immunol
, vol.150
, pp. 517-526
-
-
Denkers1
Gazzinelli2
Hieny3
Caspar4
Sher5
-
23
-
-
0026768361
-
Cytomegalovirusinduced Reactivation of Toxoplasma gondii Pneumonia in Mice: Lung Lymphocyte Phenotypes and Suppressor Function
-
+ and have suppressive activity.
-
(1992)
J Infect Dis
, vol.166
, pp. 677-681
-
-
Pomeroy1
Filice2
Hitt3
Jordan4
-
24
-
-
0026537090
-
Phenotypic Profile and Functional Characteristics of Human γδ T Cells During Acute Toxoplasmosis
-
of special interest, This, together with [25⊎], reports that patients with toxoplasmic lymphadenitis show an increase in the number of γδ T cells in peripheral blood.
-
(1992)
J Clin Microbiol
, vol.30
, pp. 729-731
-
-
De Paoli1
Basaglia2
Gennari3
Crovatto4
Modolo5
Santini6
-
27
-
-
0022195214
-
In Vivo Recombinant Interleukin-2 Administration Enhances Survival Against a Lethal Challenge with Toxoplasma gondii
-
(1985)
J Immunol
, vol.135
, pp. 4160-4163
-
-
Sharma1
Hofflin2
Remington3
-
28
-
-
0026452255
-
Human Lymphokine activated Killer Cells are Cytotoxic Against Cells Infected with Toxoplasma gondii
-
of outstanding interest, Incubation of human peripheral blood lymphocytes with recombinant IL-2 results in induction of cytotoxic activity against cells infected with T. gondii. LAK cells may be used as a novel therapeutic regimen for toxoplasmosis in immunocompromised hosts.
-
(1992)
J Exp Med
, vol.176
, pp. 1511-1519
-
-
Subauste1
Dawson2
Remington3
-
29
-
-
0024565657
-
Enhanced Antimetastatic Activity of Lymphokine-activated Killer Cells Purified and Expanded by their Adherence to Plastic
-
(1989)
Cancer Res
, vol.49
, pp. 1441-1446
-
-
Schwartz1
Vujanovic2
Hiserodt3
-
31
-
-
0026539675
-
Cytotoxic Activity Of 13-hydroxyoctadecadienoic Acid Against Toxoplasma gondii
-
of special interest, 13-hydroxyoctadecadienoic acid released by platelets stimulated by T. gondii is cytotoxic for T. gondii tachyzoites.
-
(1992)
Parasitology
, vol.105
, pp. 343-347
-
-
Henderson1
Chi2
-
32
-
-
0027476561
-
Mucosal and Systemic Cellular Immune Responses Induced by Toxoplasma gondii Antigens in Cyst Orally Infected Mice
-
of special interest, Oral infection with T. gondii is associated with an in vitro proliferative response of mesenteric lymph node and Peyer's patch lymphocytes to T. gondii antigen that precedes the proliferative response of splenic lymphocytes.
-
(1993)
Immunology
, vol.78
, pp. 421-429
-
-
Chardes1
Velge-Roussel2
Mevelec3
Mevelec4
Buzonigatel5
Bout6
-
33
-
-
0022640110
-
Secretory IgA Specfic for Toxoplasma gondii
-
(1986)
J Immunol
, vol.136
, pp. 2640-2643
-
-
McLeod1
Mack2
-
34
-
-
0027064481
-
Human Toxoplasma gondii-specific Secretory Immunoglobulin A Reduces T. gondii Infection of Enterocytes in Vitro
-
of special interest, Human secretory IgA specific for T. gondii reduces in vitro infectivity of tachyzoites of the parasite for enterocytes.
-
(1992)
J Clin Invest
, vol.90
, pp. 2585-2592
-
-
Mack1
McLeod2
-
35
-
-
0026816093
-
Toxoplasma gondii The Role Of a 30-kDa Surface Protein in Host Cell Invasion
-
of special interest, A mAb to p30 was found to inhibit invasion of mammalian cells by T. gondii.
-
(1992)
Exp Parasitol
, vol.74
, pp. 106-111
-
-
Grimwood1
Smith2
-
38
-
-
0026675678
-
Kinetics of Cytokine mRNA Production in the Brains of Mice with Progressive Toxoplasmic Encephalitis
-
of special interest, This study reports expression of mRNA encodong a number of inflammatory cytokines in the brains of mice with TE. Interestingly, a dichotomy in IL-2 and IL-4 mRNA levels in these mice was observed.
-
(1992)
Eur J Immunol
, vol.22
, pp. 2317-2322
-
-
Hunter1
Roberts2
Alexander3
-
40
-
-
0027474099
-
Expression of Major Histocompatibility Complex Class II Antigens and Levels of Interferon-γ, Tumour Necrosis Factor, Interleukin-6 in Cerebrospinal Fluid and Serum in Toxoplasma gondii-infected SCID and Immunocompetent C.B.-17
-
of special interest, Serum and CSF from SCID mice infected with T. gondii contains IFN-γ. The authors suggest that NK cells may be the source of this IFN-γ.
-
(1993)
Immunology
, vol.78
, pp. 430-435
-
-
Schluter1
Deckert-Schluter2
Schwendemann3
Brunner4
Hof5
-
42
-
-
0026691883
-
A Protective Role for Endogenous Tumor Necrosis Factor In Toxoplasma gondii Infection
-
of outstanding interest, Treatment with anti-TNF-a antibody resulted in death of mice infected with an avirulent strain of T. gondii.
-
(1992)
Infect Immun
, vol.60
, pp. 1979-1983
-
-
Johnson1
-
43
-
-
0008097938
-
Role of Tumour Necrosis Factor in Chronic Murine Toxoplasma gondii Encephalitis
-
of special interest, Administration of anti-TNF-a antibody increased the number of cysts of T. gondii in the brains of infected mice. In addition, number of cysts decreased after treatment with TNF-α.
-
(1992)
Immunol Infect Dis
, vol.2
, pp. 61-68
-
-
Chang1
Pechere2
Piguet3
-
45
-
-
0026581351
-
Polymorphisms in the Tumor Necrosis Factor α (TNF-α) Gene Correlate with Murine Resistance to Development of Toxoplasmic Encephalitis and with levels of TNF-α mRNA in Infected Brain Tissue
-
of special interest, Resistance to TE could be correlated with specific restriction length polymorphisms and microsatellite variants in the gene encoding TNF-α.
-
(1992)
J Exp Med
, vol.175
, pp. 683-688
-
-
Freund1
Sgarlato2
Jacob3
Suzuki4
Remington5
-
46
-
-
0026491049
-
Endogenous Tumor Necrosis Factor α is Required for Enhanced Antimicrobial Activity Against Toxoplasma gondii and Listeria monocytogenes in Recombinant γ Interferon-treated Mice
-
of special interest, In vivo administration of anti-TNF-α antibodies inhibited activity against T. gondii mediated by IFN-γ and release of RNIS by murine macrophages.
-
(1992)
Infect Immun
, vol.60
, pp. 5107-5112
-
-
Langermans1
van der Huist2
Nibbering3
van Furth4
-
47
-
-
0026575339
-
IFN-γ-induced Larginine-dependent Toxoplasmastatic Activity in Murine Peritoneal Macrophages is Mediated by Endogenous Tumor Necrosis Factor-α
-
of outstanding interest, Reports, in vitro studies indicating that TNF-α is involved in tile activation of murine macrophages to display activity against T. gondii and increased production of RNIs mediated by IFN-γ.
-
(1992)
J Immunol
, vol.148
, pp. 568-574
-
-
Langermans1
van der Hulst2
Nibbering3
Hiemstra4
Fransen5
van Furth6
-
48
-
-
0026529405
-
IL-10 Inhibits Parasite Killing and Nitrogen Oxide Production by IFN-γ activated Macrophages
-
of special interest, IL-10 prevents IFN-γ from inducing activity against T. gondii and increasing production of RNIs by murine macrophages.
-
(1992)
J Immunol
, vol.148
, pp. 1792-1796
-
-
Gazzinelli1
Oswald2
James3
Sher4
-
49
-
-
0026781705
-
In Vitro Effects of Interleukin-4 on Interferon-γ-induced Macrophage Activation
-
of special interest, IL-4 has no effect on activity against T. gondii and the increased production of RNIs induced by the action of IFN-γ on murine macrophages.
-
(1992)
Immunology
, vol.76
, pp. 553-559
-
-
Appelberg1
Orme2
Pinto de Sousa3
Silva4
-
50
-
-
0026698101
-
SCID Mouse Models of Acute and Relapsing Chronic Toxoplasma gondii Infections
-
of outstanding interest, Description of an animal model of toxoplasmosis and TE in SCID mice that mimics disease observed in AIDS patients.
-
(1992)
Infect Immun
, vol.60
, pp. 3719-3724
-
-
Johnson1
-
51
-
-
0026527971
-
Expression, Characterization, and Serologic Reactivity of Recombinant Surface Antigen p22 of Toxoplasma gondii
-
of special interest, Recombinant p22 antigen is recognized by sera from individuals infected with T. gondii especially those with a recent infection.
-
(1992)
J Clin Microbiol
, vol.30
, pp. 1127-1133
-
-
Parmley1
Sgarlato2
Mark3
Prince4
Remington5
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