A Dose-Ranging Study of Daily Maintenance Intravenous Foscarnet Therapy for Cytomegalovirus Retinitis in AIDS

Journal of Infectious Diseases

Volumn 168, Issue 2, 1993, Pages 444-448

  Jacobson, Mark A ^a,b,c,d,e   Causey, Dennis ^a,b,c,d,e   Polsky, Bruce ^a,b,c,d,e   Hardy, David ^a,b,c,d,e   Chown, Marilyn ^a,b,c,d,e   Davis, Roger ^a,b,c,d,e   Donnell, James J O ^a,b,c,d,e   Kuppermann, Baruch D ^a,b,c,d,e,f   Heinemann, Murk Hein ^a,b,c,d,e   Holland, Gary N ^a,b,c,d,e   Mills, John ^a,b,c,d,e,f   Feinberg, Judith E ^a,b,c,d,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOSCARNET;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL FEATURE; CYTOMEGALOVIRUS; DISEASE ACTIVITY; DOSE RESPONSE; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; FEVER; HUMAN; HYPOCALCEMIA; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; ORAL DRUG ADMINISTRATION; PANCYTOPENIA; PATIENT COMPLIANCE; PRIORITY JOURNAL; PROTEINURIA; RETINA DETACHMENT; RETINITIS; RISK ASSESSMENT; STATISTICAL ANALYSIS; SURVIVAL RATE;

ADOLESCENT; ADULT; AGED; AIDS-RELATED OPPORTUNISTIC INFECTIONS; CYTOMEGALOVIRUS INFECTIONS; FOSCARNET; HUMAN; INJECTIONS, INTRAVENOUS; MIDDLE AGE; RETINITIS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027219241     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/168.2.444     Document Type: Article

References (15)

1. Jacobson MA, O'Donnell JJ, Porteus D, Brodie HR, Feigal D, Mills J. Retinal and gastrointestinal disease due to cytomegalovirus in patients with acquired immune deficiency syndrome: Prevalence, natural history and response to ganciclovir therapy. Q J Med 1988; 67: 473-86.
2. Jabs DA, Enger C, Bartlett JG. Cytomegalovirus retinitis and acquired immunodeficiency syndrome. Arch OphthalmoI1989; 107: 75-80.
3. Studies of Ocular Complications ofAIDS Research Group, AIDS Clinical Trials Group. Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis. N Engl J Med 1992; 326: 213-20.
4. Jacobson MA, Causey D, Polsky B, Dose-ranging study of daily intravenous maintenance foscarnet therapy for cytomegalovirus retinitis in AIDS patients [abstract FB96]. In: Programs and abstracts: VI International Conference on AIDS (San Francisco). San Francisco: University of California, 1990.
5. Jacobson MA, O'Donnell JJ, Mills J. Tolerance and efficacy of intermittent intravenous foscarnet for cytomegalovirus retinitis in patients with AIDS. Antimicrob Agents Chemother 1989; 33: 736-41.
6. Aweeka F, Gambertoglio J, Mills J, Jacobson MA. Pharmacokinetics of intermittently administered intravenous foscarnet in treatment of AIDS patients with serious CMV retinitis. Antimicrob Agents Chemother 1989; 33: 742-5.
7. Walmsley SL, Chew E, Read SE, Treatment of cytomegalovirus retinitis with trisodium phosphonoformate hexahydrate (foscarnet). J Infect Dis 1988; 157: 569-72.
8. Jacobson MA, O'Donnell JJ, Brodie HR, Wofsy C, Mills J. Randomized prospective trial ofganciclovir maintenance therapy for cytomegalovirus retinitis. J Med Virol 1988; 25: 339-49.
9. Deray G, Martinez F, Katlama C, Foscarnet nephrotoxicity: Mechanism, incidence and prevention. Am J Nephrol 1989; 9: 316-21.
10. Jacobson MA, Crowe S, Levy J, Effect of foscarnet therapy on infection with human immunodeficiency virus in patients with AIDS. J Infect Dis 1988; 158: 862-5.
11. Reddy MM, Grieco MH, McKinley GF, Effect of foscarnet on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis. J Infect Dis 1992; 166: 607-10.
12. Skolnick PR, Kosloff BR, Hirsch MS. Bidirectional interactions between human immunodeficiency virus type I and cytomegalovirus. J Infect Dis 1988; 157: 508-14.
13. Webster A, Cook DG, Emery VC, Cytomegalovirus infection and progression towards AIDS in hemophiliacs with human immunodeficiency virus infection. Lancet 1989; 2: 63-5.
14. Bonetti A, Weber R, Vogt MW, Wunderli W, Siegenthaler W, Luthy R. Co-infection with human immunodeficiency virus-type I (HIV-I) and cytomegalovirus in two intravenous drug users. Ann Intern Med 1989; 111: 293-6.
15. Jacobson MA, Gambertoglio JG, Aweeka FT, Causey OM, Portale AA. Foscarnet-induced hypocalcemia and foscarnet effects on calcium and phosphorus metabolism. J Clin Endocrinol Metab 1991; 72: 1130-5.