Preferential expression in mushroom bodies of the catalytic subunit of protein kinase A and its role in learning and memory

Neuron

Volumn 11, Issue 2, 1993, Pages 197-208

  Skoulakis, Efthimios M C ^a   Kalderon, Daniel ^b   Davis, Ronald L ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP PHOSPHODIESTERASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVITY; ENZYME SUBUNIT; GENE EXPRESSION REGULATION; GENE ISOLATION; GENE MUTATION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEARNING; MEMORY; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; BASE SEQUENCE; BEHAVIOR, ANIMAL; BRAIN; CATALYSIS; DROSOPHILA; GENE EXPRESSION; LEARNING; MEMORY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PROTEIN KINASES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027214152     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(93)90178-T     Document Type: Article

References (44)

1. P-element-mediated enhancer detection: a versatile method to study development in Drosophila
2. Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster
3. Cellular analysis of associative learning
4. The Drosophila dunce locus: learning and memory genes in the fly
5. dunce mutants of Drosophila melanogaster: mutants defective in the cyclic AMP phosphodiesterase enzyme system
6. + channel in Drosophila larval muscle is persistently activated in dunce
7. Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons
8. cAMP-dependent protein kinase and the disruption of learning in transgenic flies
9. Neurogenetic dissection of learning and short-term memory in Drosophila
10. Purification of Drosophila cAMP-dependent protein kinase
11. Drosophila cAMP-dependent protein kinase
12. Cloning, sequence, and expression of the Drosophila cAMP-dependent protein kinase catalytic subunit gene
13. The long and the short of long-term memory—a molecular framework
14. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
15. The Drosophila sloppy paired locus encodes two proteins involved in segmentation that show homology to mammalian transcription factors
16. Isolation and characterization of the Drosophila learning/memory gene, rutabaga, using enhancer detection for mushroom body expression
17. Preferential expression of the Drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects
18. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains
19. Genetic approach to learning and memory (mnemogenetics) in Drosophila melanogaster
20. Drosophila mushroom body mutants are deficient in olfactory learning
21. Isolation and characterization of Drosophila cAMP-dependent protein kinase genes
22. Classical conditioning and sensitization share aspects of the same molecular cascade in Aplysia
23. cAMP-dependent regulation of proenkephalin by JunD and JunB: positive and negative effects of AP-1 proteins
24. Genetic investigation of cAMP-dependent protein kinase function in Drosophila development
25. Role of phosphorylation in desensitization of the β-adrenoreceptor
26. 2+/calmodulin-responsive adenylyl cyclase
27. Loss of calcium/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant
28. Regulation of transcription by cAMP dependent protein kinase
29. Neurobiology of learning and memory in honeybees
30. The cyclic AMP phosphodiesterase encoded by the Drosophila dunce gene is concentrated in the mushroom body neuropil
31. Characterization of the memory gene dunce of Drosophila melanogaster
32. cAMP evokes long-term facilitation in Aplysia sensory neurons that requires new protein synthesis
33. + currents
34. What molecular steps determine the time course of the memory for short-term sensitization in Aplysia
35. Neuronal architecture of the antennal lobe in Drosophila melanogaster
36. Persistent and transcriptionally-dependent increase in protein phosphorylation in long-term facilitation of Aplysia sensory neurons
37. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals a translational control of the segmentation gene hunchback
38. cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes
39. Drosophila learning and memory revisited
40. Classical conditioning and retention in normal and mutant Drosophila melanogaster
41. Protein phosphorylation and neuronal function
42. P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila