Aberrations of p53 gene in human hepatocellular carcinoma from china

Carcinogenesis

Volumn 14, Issue 2, 1993, Pages 169-173

  Li, Daizong ^a   Cao, Yuqing ^a   He, Lipin ^a   Wang, N J ^a,b   Gu, Jian ren ^a  

^a SHANGHAI CANCER INSTITUTE   (China)

^b Qidong Cancer Institute   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; PROTEIN P53; VIRUS DNA;

ANIMAL TISSUE; ARTICLE; CHINA; CHROMOSOME 17P; CODON; DIET; DNA SEQUENCE; GENE MUTATION; GENETIC ANALYSIS; GEOGRAPHIC DISTRIBUTION; HEPATITIS B VIRUS; HETEROZYGOSITY; HUMAN; LIVER CELL CARCINOMA; PRIORITY JOURNAL; RISK FACTOR; SINGLE STRAND CONFORMATION POLYMORPHISM;

AFLATOXIN B1; BASE SEQUENCE; BLOTTING, SOUTHERN; CARCINOMA, HEPATOCELLULAR; CHINA; CHROMOSOME ABERRATIONS; DNA, NEOPLASM; DNA, SINGLE-STRANDED; ENVIRONMENTAL EXPOSURE; GENES, P53; HEPATITIS B; HUMAN; LIVER NEOPLASMS; METHYLATION; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; RISK FACTORS;

EID: 0027210367     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/14.2.169     Document Type: Article

References (19)

1. Bosch, F.X. and Munoz, N. (1988) Epidemiology of hepatocellular carcinoma. In Bannasch, P., Keppler, D. and Weber, G. (eds) Liver Cell Carcinoma. Norwell MA, Dordrecht, Boston, London: Kluwer Academic Publishers, pp. 3-14.
2. Hollstein M., Sidransky, D., Vogelstein, B. and Harris, C.C. (1991) p53 mutations in human cancers. Science, 253, 49-53.
3. Hsu, I.C., Metcalf, R.A., Sun, T., Welsh, J.A., Wang, N.J. and Harris, C.C. (1991) Mutational hotspot in the p53 gene in human hepatocellular carcinoma. Nature, 350, 427-428.
4. Biessac, B., Kew, M., Wands, J. and Ozturlc, M. (1991) Selective G to T mutations of p53 gene in hepatocellular carcinoma from Southern Africa. Nature, 350, 429-431.
5. Ozturk, M. (1991) p53 mutation in hepatocellular carcinoma after aflatoxin exposure. Lancet, 338, 1356-1359.
6. Hayward, N.K., Walker, GJ, Graham, W. et al. (1991) Hepatocellular carcinoma mutation. Nature, 352, 764.
7. Murakami, Y., Hayashi, K., Hirohashi, S. and Seldya, T. (1991) Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. Cancer Res., 51, 5520-5525.
8. Patel, P., Stephenson, A., Scheuer, P.J. et aL (1992) p53 codon 249ser mutations in hepatocellular carcinoma patients with low aflatoxin exposure. Lancet, 339, 881.
9. Scorsone, K.A., Zbou, Y.Z., Butel, J.S. et aL (1992) p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China. Cancer Res., 52, 1635-1639.
10. Oda, T., Tsuda, H., Scarpa, A. etal. (1992) Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma. Cancer Res., 52, 3674-3678.
11. Hollstein M.C., Wild C.P., Bleicher, F. et al. (1992) p53 mutations and aflatoxin B1 exposure in hepatocellular carcinoma patients from Thailand. Int. J. Cancer, in press.
12. Kress, S., Jahn, U.-R., Buchmann, A., Bannasch, P. and Schwarz, M. (1992) p53 mutations in human hepatocellular carcinomas from Germany. Cancer Res., 52, 3220-3223.
13. Shen J.C., Lee, P.H., Huang, G.T., Chung, J.C., Cbou, H.C., Wang, J.T., Lee, H.S., Shih, L.N., Yang, P.M., Chen, D.S. and Wang, T.H. (1992) Mutation of p53 gene in hepatocellular carcinoma in Taiwan. Cancer Res., in press.
14. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning, a Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory Press, Qld Spring Harbor, NY.
15. Nigro, J.M., Baker, S.J., Preisinger, A.C., Jesup, J.M., Hostetler, R., Cleary, K., Binger, S.H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Collins, F.S., Weston, A., Modali, R., Harris, C.C. and Vogelstein, B. (1989) Mutations in the p53 gene occur in diverse human tumor types. Nature, 342, 705-708.
16. Gyllensten, U.B. and Erlich, H.A. (1988) Generation of single-strand DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. Proc. Natl Acad. Sci. USA, 85, 7652-7656.
17. Puisieux, A., Lim, S., Groopman, J. and Ozturk, M. (1991) Selective targeting of p53 gene mutational hotspots in human cancers by ecologically defined carcinogens. Cancer Res., 51, 6185-6189.
18. Ross, R.K., Yuan, J.M., Yu, M.C., Wogan, G.N., Qian, G.S., Tu, J.T., Grooptnan, J.D., Gao, Y.T. and Henderson, B.E. (1992) Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma. Lancet, 339, 943-946.
19. Sato, T., Tanigami, A., Yamakawa, K., Akiyama, F., Kasumi, F., Sakamoto, G. and Nakamura, Y. (1990) Allelotype of breast cancer cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res., 50, 7184-7189.