B‐50 (GAP‐43) in the spinal cord caudal to hemisection: Indication for lack of intraspinal sprouting in dorsal root axons

Journal of Neuroscience Research

Volumn 35, Issue 6, 1993, Pages 603-617

  Nacimiento, W ^a,c   Mautes, A ^b   Topper R ^a,c   Oestreicher, A B ^d   Gispen, W H ^d   Nacimiento, A C ^b   Noth, J ^a   Kreutzberg, G W ^c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

descending tracts; dorsal roots; plasticity; spasticity; sprouting

Indexed keywords

NEUROMODULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAT; DENSITOMETRY; DORSAL ROOT; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NERVE ENDING; NERVE FIBER; NERVE FIBER DEGENERATION; NERVE FIBER REGENERATION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD HEMISECTION;

ANIMAL; AXONS; BIOLOGICAL MARKERS; CATS; GAP-43 PROTEIN; IMMUNOHISTOCHEMISTRY; MEMBRANE GLYCOPROTEINS; MICROSCOPY, ELECTRON; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; NEUROFILAMENT PROTEINS; NEURONAL PLASTICITY; PERFUSION; SCIATIC NERVE; SPINAL CORD; SUPPORT, NON-U.S. GOV'T;

EID: 0027209991     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.490350604     Document Type: Article

References (70)

1. On the distribution of GAP‐43 and its relation to serotonin in adult monkey and cat spinal cord and lower brainstem
2. Distribution of GAP‐43 mRNA in the brain stem of adult rats as evidenced by in situ hybridization: localization within monoaminergic neurons
3. The relationship of GAP‐43 to the development and plasticity of synaptic connections
4. Anatomical distribution of the growth‐associated protein GAP‐43/B‐50 in the adult rat brain
5. Localization of the growth‐associated phosphoprotein GAP‐43 (B‐50, F1) in the human cerebral cortex
6. The pattern of GAP‐43 immunostaining changes in the rat hippocampal formation during reactive synaptogenesis
7. Phosphorylation of the presynaptic protein B‐50 (GAP‐43) is increased during electrically induced long‐term potentiation
8. Distribution of the growth associated protein GAP‐43 in central processes of axotomized primary afferents in the adult rat spinal cord; presence of growth cone‐like structures
9. GAP‐43 is expressed by nonmyelin‐forming Schwann cells of the peripheral nervous system
10. The distribution of GAP‐43 in the normal rat spinal cord
11. Up‐regulation of GAP‐43 and growth of axons in rat spinal cord after compression injury
12. Inhibition of the noradrenalin release by antibodies to B‐50(GAP‐43)
13. GAP‐43 gene expression during development: persistence in a distinctive set of neurons in the mature central nervous system
14. Role of the growth‐associated protein B‐50/GAP‐43 in neuronal plasticity
15. Spared‐root deafferentation of cat's hindlimb: hierarchical regulation of pathways mediating recovery of motor behavior
16. Recovery of movement and axonal sprouting may obey some of the same laws
17. Lack of sprouting and its presence after lesions of the cat spinal cord
18. GAP‐43‐What does it do in the growth cone?
19. B‐50/GAP43 is localized at the cytoplasmic side of the plasma membrane in developing and adult rat pyramidal tract
20. Neuronal and glial changes in the rat phrenic nucleus occurring within hours after spinal cord injury
21. Decussation of bulbospinal respiratory axons at the level of the phrenic nuclei in adult rats: a possible Substrate for the crossed phrenic phrenic Phenomenon
22. Neuronal organization of micturition
23. Sprouting of dorsal root axons
24. A comparison of axonal numbers in dorsal roots following spinal cord hemisection in neonate and adult rats
25. Fine structure of growth cones in the upper dorsal horn of the adult primate spinal cord in the course of reactive synapto‐neogenesis
26. Light and electron microscopic localization of B‐50 (GAP43) in the rat spinal cord during transganglionic degenerative atrophy and regeneration
27. Anatomy of descending pathways
28. Deafferentation‐induced expansion of saphenous terminal field labelling in the adult rat dorsal horn following pronase injection of the sciatic nerve
29. Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP‐43 in the dentate gyrus of the adult rat
30. Electron microscopy of non‐neuronal cellular changes accompanying neural degeneration in thalamic nuclei of the rabbit: II. Reactive elements within the neuropil
31. The reactive oligodendrocyte: An electronmicroscopic study of cerebral cortex following alpha particle irradiation
32. Sprouting as a cause of spasticity
33. Propriospinal and supraspinal projections to the motor nuclei in the cat spinal cord
34. Sprouting ofperipherally regenerating primary sensory neurones in the adult central nervous System
35. Denervation‐induced intraspinal synaptogenesis of calcitomn gene‐related peptide containing primary afferent terminals
36. Intraspinal sprouting of Calcitonin gene‐related peptide containing primary afferents after deafferentation in the rat
37. Modifiability of spinal synapses
38. Immunocytochemical detection of the growth‐associated protein B‐50 by newly characterized monoclonal antibodies in human brain and muscle
39. Restitution of function and collateral sprouting in the cat spinal cord: the partially hemisected animal
40. Replacement of synaptic terminals in lamina II and Clarke's nucleus after unilateral dorsal rhizotomy in adult cats
41. The two major phosphoproteins in growth cones are probably identical to two protein kinase C Substrates correlated with persistence of long‐term potentiation
42. Trends in the pathophysiology and pharmacotherapy of spasticity
43. Comparison of immunohistochemical distribution of the phosphoprotein B‐50 in the cerebellum and hippocampus of the immature and adult rat brain
44. Affinity‐purified anti‐B‐50 protein antibody: interference with the function of the phosphoprotein B‐50 in synaptic plasma membranes
45. Plasticity of dorsal root and descending serotoninergic projections after partial deafferentation of the adult rat spinal cord
46. Synapse formation in the septal nuclei of adult rats
47. Absence of intraspinal sprouting in dorsal root axons caudal to a partial spinal hemisection: a horseradish peroxidase transport study
48. An examination of intraspinal sprouting in dorsal root axons with the tracer horseradish peroxidase
49. Locomotion of the adult chronic spinal cat and its modification by monoaminergic agonists and antagonists
50. Immunocytochemical analysis of serotonergic axons in laminae l and II of the lumber spinal cord of the cat
51. Fate of GAP‐43 in ascending spinal axons of DRG neurons after peripheral nerve injury: delayed accumulation and correlation with regenerative potential
52. Axonal growth‐associated proteins
53. Time‐dependent differences in the increase in GAP‐43 expression in dorsal root ganglion cells after peripheral axotomy
54. GAP‐43 immunoreactivity is widespread in the autonmic neurons and sensory neurons of the rat
55. Recovery of substance P but not somatostatin in the cat spinal cord after unilateral rhizotomy: a quantitative study
56. Sciatic nerve transection produces death of dorsal root ganglion cells and reversible loss of substance P in the spinal cord
57. Calcitonin gene‐related peptide immunoreactivity in the cat lumbosacral spinal cord and the effects of multiple dorsal rhizotomies
58. Synaptic plasticity in the red nucleus and its possible behavioral correlates
59. Expression of growth‐associated protein B‐50 (GAP43) in dorsal root ganglia and sciatic nerve during regenerative sprouting
60. Conelation between GAP43 and nerve growth factor receptors in rat sensory neurons
61. GAP‐43 expression in macroglial cells: potential functional significance
62. The growth‐associated protein GAP‐43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury
63. Peripheral nerve injury triggers central sprouting of myelinated afferents
64. Denervation of motor endplate results in the rapid expression by terminal Schwann cells of the growth‐associated protein GAP‐43