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Volumn 49, Issue 17, 1993, Pages 3521-3532

Cyclopropanes as conformationally restricted peptide isosteres. Design and synthesis of novel collagenase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; COLLAGENASE INHIBITOR; CYCLOPROPANE DERIVATIVE; PSEUDOPEPTIDE;

EID: 0027207873     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)90212-1     Document Type: Article
Times cited : (66)

References (49)
  • 1
    • 0000327897 scopus 로고
    • For some reviews of peptide mimics, see, E.J. Ariëns, Academic Press Inc, New York
    • (1980) Drug Design , vol.10 , pp. 119-143
    • Farmer1
  • 26
    • 0025074114 scopus 로고
    • For other examples of cyclopropanes in peptide mimics, see
    • (1990) Tetrahedron , vol.46 , pp. 2231
    • Stammer1
  • 33
    • 84918208750 scopus 로고    scopus 로고
    • Dickens, J. P.; Donald, D. K.; Kneen, G.; McKay, W. R. United States Patents #4,599,361 (July 8, 1986) and #4,743,587 (May 10, 1988).
  • 36
    • 0005871619 scopus 로고
    • The limit of detection of the minor enantiomer in such experiments is generally accepted to be ± 3%; therefore, an enantiomeric excess of ≥94% is denoted since only one enantiomer was detected.
    • (1979) J. Org. Chem. , vol.44 , pp. 2165
    • Jakovac1    Jones2
  • 41
    • 84918208749 scopus 로고    scopus 로고
    • 2. (c) HCl, dioxane, HOAc] according to procedures previously developed at G. D. Searle. We thank Dr. Stevan Djuric for the experimental details.
  • 48
    • 84918208747 scopus 로고    scopus 로고
    • 2, 0 → °C, 3 h).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.