P53 gene mutation and integrated hepatitis b viral DNA sequences in human liver cancer cell lines

Carcinogenesis

Volumn 14, Issue 5, 1993, Pages 987-992

  Hsu, I C ^a   Tokiwa, T ^a,b   Bennett, W ^a,b   Metcalf, R A ^a,b   Welsh, J A ^a,b   Sun, T ^a,c   Harris, C C ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c CANCER HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; PROTEIN P53; VIRUS DNA;

AMINO ACID SUBSTITUTION; ARTICLE; DELETION MUTANT; GENE MUTATION; HEPATITIS B; HEPATITIS B VIRUS; HEPATOBLASTOMA; HUMAN; HUMAN CELL; JAPAN; LIVER CELL CARCINOMA; ONCOGENE RAS; POINT MUTATION; PRIORITY JOURNAL; RISK FACTOR; SOUTH AFRICA; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE; VIRUS DNA CELL DNA INTERACTION;

BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CELL LINE; DNA, NEOPLASM; DNA, VIRAL; GENES, P53; HEPATITIS B VIRUS; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN P53; SUPPORT, U.S. GOV'T, NON-P.H.S.; TUMOR CELLS, CULTURED; VIRUS INTEGRATION;

EID: 0027207612     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/14.5.987     Document Type: Article

References (55)

1. Di Bisceglie, A.M., Rustgi, V.K., Hoofnagle, J.H., Dusheiko, G.M. and Lotze, M.T. (1988) Hepatocellular carcinoma. Ann. Intern. Med., 108, 390-401
2. Popper, H., Shafritz, D.A. and Hoofnagle, J.H. (1987) Relation of hepatitis B virus carrier state to hepatocellular carcinoma. Hepatology, 7, 764-772
3. Ganem, D. and Varmus, H.E. (1987) The molecular biology of the hepatitis B viruses. Anna. Rev. Biochem., 56, 651-693
4. Wogan, W.N. (1992) Aflatoxins as risk factors for hepatocellular carcinoma in humans. Cancer Res., 52, 2114s-2118s
5. Harris, C.C. (1990) Hepatocellular carcinogenesis: recent advances and speculation. Cancer Ceils, 2, 146-148
6. Ross, R.K., Yuan, J.M., Yu, M.C., Wogan, G.N., Qian, G.S., Tu J T., Groopman, J.D., Gao, Y.T. and Henderson, B.E. (1992) Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma. Lancet, 339, 943-946
7. Bishop, J.M. (1991) Molecular themes in oncogenesis. Cell, 64, 235-248
8. Weinberg, R.A. (1991) Tumor suppressor genes. Science, 254, 1138-1146
9. Harris, C.C. (1991) Chemical and physical carcinogenesis: Advances and perspectives for the 1990s. Cancer Res., 51, 5023s-5044s
10. Levine, A.J., Momand J. and Finlay, C.A. (1991) The p53 tumor suppressor gene. Nature, 351, 453-456
11. Hollstein, M., Sidransky, D., Vogelstein, B. and Harris, C.C. (1991) p53 mutations in human cancers. Science, 253, 49-53
12. Soussi, T., Fromental, C. and Mary, P. (1990) Structural aspects of the p53 protein in relation to gene evolution. Oncogene, 5, 945-952
13. Malkin, D., Li F., Strong, L., Fraumeni, J., Nelson, C., Kim, D., Kassel, J., Gryka, M., Biochoff, F., Tainsky, M. and Friend, S. (1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcoma, and other neoplasms. Science, 250, 1233-1238
14. Jones, P.A., Buckley, J.D., Henderson, B.E., Ross, R.K. and Pike, M.C. (1991) From gene to carcinogen: A rapidly evolving field in molecular epidemiology. Cancer Res., 51, 3617-3620
15. Mazur, M. and Glickman, B. (1988) Sequence specificity of mutations induced by benzo[a]pyrene-7, 8-diol-9, 10-epoxide at endogenous APRT gene in CHO cells. Somat. Cell Mol Genet., 14, 393-400
16. Wang P., Bennett, R.A.O. and Povirk, L.F. (1990) Melphalan-induced mutagenesis in an SV40 based shuttle vector predominance of A:T.-T:A. transversions. Cancer Res., 50, 7527-7531
17. Loechler, E., Green, C. and Essigman, J. (1984) In vivo mutagenesis by (Amethylguanine built into a unique site in viral genome. Proc. Natl. Acad. Sd. USA, 81, 6271-6275
18. Quintanilla, M., Brown, K., Ramsden, M. and Balmain A. (1986) Carcinogen specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature, 322, 78-80
19. Stowers, S.J., Wiseman, R.W., Ward J.M., Miller, E.C., Miller, J.A., Anderson, M.W. and Alassandra, E. (1988) Detection of activated protooncogenes in A'-nitrosodiethylamine induced liver tumors a comparison between B6C3F, mice and Fischer 344 rats. Carcinogenesis, 9, 271-276
20. Sukumar, S. and Barbacid, M. (1990) Specific patterns of oncogene activation in transplacentally induced tumors. Proc. Natl Acad. Sd. USA, 87, 718-722
21. Brash, D.E., Rudolph, J.A., Simon, J.A., Lin, A., McKenna, G.J., Baden, H.P., Halperin, A.J. and Ponlen, J. (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc. Natl. Acad Sd. USA, 88, 10124-10128
22. Hsu D.C., Metcalf, R.A., Sun, T., Welsh, J. and Harris, C.C. (1991) p53 gene mutational hotspot in human hepatocellular carcinomas from Qidong, China. Nature, 350, 427-428
23. Scorsone, K.A., Zhou, Y., Butel, J.S. and Slagle, B.L. (1992) p53 mutation cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinoma from China. Cancer Res., 52, 1635-1639
24. Li D., Cao, Y., He L., Wang N.J. and Gu J. (1993) Aberration of p53 gene in human hepatocellular carcinoma from China. Carcinogenesis, in press
25. Ozturk, M. et al (1991) p53 mutation in hepatocellular carcinoma after aflatoxin exposure. Lancet, 338, 1356-1359
26. Bressac B, Kew, M., Wands, J. and Ozturk, M. (1991) Selective Gto T mutation of p53 gene in hepatocellular carcinoma from southern Africa. Nature, 350, 429-431
27. Murakami, Y., Hayashi, K. and Sekiya, T. (1991) Detection of aberrations of the p53 alleles and the gene transcript in human tumor cell lines by singlestrand conformation polymorphism analysis. Cancer Res., 51, 3356-3361
28. Oda, T., Tsuda, H., Scarpa A., Sakamoto, M. and Hirohashi, S. (1992) Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma. Cancer Res., 52, 3674-3678
29. Kress, S., Jahn, U., Buchmann, A., Bannasch, P. and Schwarz, M. (1992) p53 mutation in human hepatocellular carcinomas from Germany. Cancer Res., 52, 3220-3223
30. Rao, B.V. and Green, A.A. (1987) Hepatic tumors in children and adolescents. In Wanebo, H.J. (ed.), Hepatic and Biliary Cancers. Marcel Dekker, New York, pp. 187-218
31. Huh, N. and Utakoji, T. (1981) Production of HBs-antigen by two new human hepatoma cell lines and its enhancement by dexamethasone. Gann, 72, 178-179
32. Nakabayashi, H., Taketa, K., Miyano, K., Yamane, Y. and Sato, J. (1982) Growth of human hepatoma cell lines with differentiated functions in chemically defined medium. Cancer Res., 42, 3858-3863
33. Tsurimoto, T., Fujiyama, A. and Matsubara, K. (1987) Stable expression and replication of hepatitis B virus genome in an integrated state in a human hepatoma cell line transfected with the cloned viral DNA. Proc. Natl. Acad Sd. USA, 84, 444-448
34. Doi, I., Namba, M. and Sato, J. (1975) Establishment and some biological characteristics of human hepatoma cell lines. Gann, 66, 385-392
35. Doi, I. (1976) Establishment of a cell line and its clonal sublines from a patient with hepatoblastoma. Gann, 67, 1-10
36. Aden, D.P., Fogel, A., Plotkin, S., Damjanov, I. and Knowles, B.B. (1979) Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature, 282, 615-616
37. Fogh J. and Trempe, G. (1976) New human tumor cell line. In Fogh, J. (ed.), Human Tumor Cells In Vitro. Plenum Press, New York, pp. 115-119
38. Fogh, J., Wright, W.C. and Loveless, J.D. (1977) Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J. Natl Cancer Inst., 58, 209-214
39. Alexander J.J., Bey, E.M., Whitcutt, M. and Gear, J. (1976) Adaptation of cells derived from human malignant tumours to growth in vitro. S. Afr. J. Med. Sd., 41, 89-93
40. Sanger, F., Niclden, S. and Coulson, A.R. (1977) DNA sequencing chain terminating inhibitors. Proc. Natl Acad. Sd. USA, 74, 5463-5467
41. Metcalf, R.A., Welsh, J.A., Bennett, W.P., Seddon, M.B., Lehman T.A., Pelin, K., Linnainmaa, K., Tammilehto, L., Mattson, K., Gerwin, B.I. and Harris, C.C. (1992) p53 and Kirsten-raj mutations in human mesothelioma cell lines. Cancer Res., 52, 2610-2615
42. Bennett, W.P., Hollstein, M.C., He A., Zhu, S.M., Resau, J.H., Tramp, B.F., Metcalf, R.A., Welsh, J.A., Lane, D.P. and Harris, C.C. (1992) Archival analysis of p53 gene and protein alternations in Chinese esophageal cancer. Oncogene, 6, 1779-1784
43. Kobayashi, M. and Koike, K. (1984) Complete nucleotide sequence of hepatitis B virus DNA of subtype adr and its conserved gene organization. Gene, 30, 227-232
44. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 9.31-9.57
45. Richards, C.A., Short, S.A., Thorgeirsson, S.S. and Huber, B.E. (1990) Characterization of a transformatdng N-rut gene in the human hepatoblastoma cell line hep G 2 additional evidence for the importance of c-myc and ras cooperation in hepatocarcinogenesis. Cancer Res., 50, 152-527
46. McMahon, G., Davis, E.F., Huber, I.J., Kim, Y. and Wogan, G.N. (1990) Characterization of c-Ki-rur and N-rar oncogenes in aflatoxin Binduced rat liver tumors. Proc. Nad. Acad. Sci. USA, 87, 1104-1108
47. Fujimoto, Y., Hampton, L.L., Luo, L., Wirth, PJ. and Thorgeirsson, S.S. (1992) Low frequency of p53 gene mutation in tumor induced by aflatoxin B, in nonhuman primates. Cancer Res., 52, 1044-1046
48. Trottier, Y., Waithe, W.J. and Anderson, A. (1992) Kinds of mutations induced by AFBj in a shuttle vector replicating in human cells transiently expressing cytochrome p450 IA2 cDNA. Mol. Carcinogenesis, 6, 140-147
49. Lehman T.A. and Harris, C.C. (1993) Mutational spectra of protooncogenes and tumor suppressor genes: clues to predict cancer etiology. IARC Monograph, in press
50. Aguilar JL., Pourzand, C., Hussain, P. and Cerutd, P. (1993) Genotypic mutation analysis in cancer related genes. Int. J. Cancer, in press
51. Fssigmann, L M, Croy, R.G., Nadzan, A.M., Busby, W.F. Jr, Reinhold, V.N., Buchi, G. and Wogan, G.N. (1977) Structural identification of the major DNA adduct formed by aflatoxin B, in vitro. Proc. Natl. Acad Sci. USA, 74, 1870-1874
52. Puisieux A., Lin, S., Groopman, J. and Ozturk JC M. (1991) Selective targeting of p53 gene mutational hotspots in human cancers by biologically defined carcinogens. Cancer Res., 51, 6185-6189
53. Harris, A.L. (1991) Telling changes of base. Nature, 350, 377-378
54. Oda, T., Tsuda, H., Scarpa, A., Sakamoto, M. and Hirohashi, S. (1992) p53 gene mutational spectrum in hepatocellular carcinoma. Cancer Res., 52, 6358-6364
55. Bressac, B., Galvin, K.M., Liang, T.J., Isselbacher, K.J., Wands, J.R. and Ozturk, M. (1990) Abnormal structure and expression of p53 gene in human hepatocellular carcinoma. Proc. Natl. Acad Sci. USA, 87, 1973-1977