A molecular variant of angiotensinogen associated with preeclampsia

Nature Genetics

Volumn 4, Issue 1, 1993, Pages 59-61

  Ward, K ^a   Hata, A ^b   Jeunemaitre, X ^a,c   Helin, C ^a   Nelson, L ^a   Namikawa, C ^b   Farrington, P F ^a   Ogasawara, M ^b   Suzumori, K ^b   Tomoda, S ^d   Berrebi, S ^c   Sasaki, M ^b   Corvol, P ^c   Lifton, R P ^a,e   Lalouel, J M ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c HÔPITAL BROUSSAIS   (France)

^d OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSINOGEN;

ARTICLE; CAUCASIAN; DISEASE ASSOCIATION; ESSENTIAL HYPERTENSION; FEMALE; GENETIC VARIABILITY; HUMAN; HYPERTENSION; JAPAN; MATERNAL HYPERTENSION; MORBIDITY; MORTALITY; PREECLAMPSIA; PROTEIN VARIANT; PROTEINURIA;

ANGIOTENSINOGEN; BASE SEQUENCE; CAUCASOID RACE; COMPARATIVE STUDY; FEMALE; HUMAN; HYPERTENSION; MOLECULAR SEQUENCE DATA; MONGOLOID RACE; PARITY; POLYMERASE CHAIN REACTION; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; RENIN-ANGIOTENSIN SYSTEM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; VARIATION (GENETICS);

EID: 0027205144     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng0593-59     Document Type: Article

References (23)

1. Chesley, L.C. & Lindheimer, M.D. Renal hemodynamics and intravascular volume in normal and hypertensive pregnancy. In Handbook of Hypertension, Vol 10: Hypertension in Pregnancy (ed. Rubin P.C.) 38-65 (Elsevier, Amsterdam, 1988).
2. Wallenburg, H.C.S. Hemodynamics in hypertensive pregnancy. InHandbook of Hypertension, Vol 10: Hypertension in Pregnancy (ed. Rubin P.C.) 66-101 (Elsevier, Amsterdam, 1988).
3. August, P. & Sealey, J.E. The renin-angiotnesin system in normal and hypertensive pregnancy and in ovarian function. In Hypertension: Pathophysiology, Diagnosis, and Management (eds Laragh, J.H. & Brenner, B.M.) 1761-1778 (Raven, New York, 1990).
4. Lynch, K.R. & Peach, M.J. Biochemistry and molecular biology.Hypertension 17, 263-269 (1991).
5. Tewksbury, D.A. Angiotensinogen: biochemistry and molecular biology. In Hypertension: Pathophysiology, Diagnosis, and Management (eds Laragh, J.H. & Brenner, B.M.) 1197-1216 (Raven, New York, 1990).
6. Tewksbury, D.A. & Dart, R.A. High molecular weight angiotensinogen levels in hypertensive pregnant women. Hypertension 4, 729-734 (1982).
7. Gant, N.F., Whalley, P.J., Everett, R.B., Worley, R.J. & MacDonald, P.C. Control of vascular reactivity in pregnancy. Am. J. kidney Dis. 9, 303-307 (1987).
8. Liston, W.A., & Kilpatrick, D.C. Is genetic susceptibility to pre-eclampsia conferred by homozygosity for the same signle recessive gene in mother and fetus? Br. J. Obstet. Gynecol. 98, 1079-1086 (1991).
9. Cooper, D.W., Hill, J.A. & Chesley, L.C. Genetic control of susceptibility to eclampsia and miscarriage. Br. J. Obstet. Gynecol. 95, 644-653 (1988).
10. Chesley, L.C., Annitto, J.E., & Cosgrove, R.A. The remote prognosis of eclamptic women. Am. J. Obstet. Gynecol. 124, 446-452 (1976).
11. Fischer, K.A., Luger, L., Spargo, B.H. & Lindheimer, M.D. Hypertension in pregnancy: clinical pathologic correlations and remote prognosis. Medicine60, 267-272 (1981).
12. Gaillard, I., Clauser, E. & Corvol, P. Structure of human angiotensinogen gene. DNA 8, 87-99 (1989).
13. Gaillard, I., Mattei, M.G., Clauser, E. & Corvol, P. Assignment by in situhybrization of the angiotensinogen gene to chromosome band 1q4, the same region as the human renin gene. Hum. Genet. 84, 341-343 (1990).
14. Jeunemaitre, X. et al. Molecular basis of human hypertension: role of angiotensiongen. Cell 71, 169-180 (1992).
15. Laragh, J.H. The pill, hypertension, and the toxemias of pregnancy. Am. J. Obstet. Gynecol. 109, 210-213 (1971).
16. Schwartz, M.L. & Brenner, W.E. Pregnancy-induced hypertension presenting with life-threatening thrombocytopenia. Am. J. Obstet. Gynecol.146, 756-761 (1983).
17. Jacobson, C. in Utah in Demographic Perspective (eds Martin, T.K., Heaton, T.B. & Bahr, S.J.) 165-179 (Signature Press, New York).
18. Taylor, D.J. The epidemiology of hypertension during pregnancy. InHandbook of Hypertension, Vol 10: Hypertension in Pregnancy (ed. Rubin P.C.) 223-240 (Elsevier, Amsterdam, 1988).
19. Musey, V.C. et al. Long term effects of a first pregnancy on the hormonal environment: estrogens and androgens. J. clin. Endocrin. Metab. 64, 111-118 (1987).
20. Wang, D.Y. et al. The permanent effect of reproductive events on blood prolactin levels and its relation to breast cancer risk: a population study of postmenopausal women. Eur. J. Cancer clin. Oncol. 24, 1225-1231 (1988).
21. American College of Obstetrics and Gynecology Pregnancy induced hypertension. Technical Bulletin, 91 (1986).
22. Sibai, B.M. et al. Maternal-perinatal outcome associated with the syndrome of hemolysis elevated liver enzymes and low platelets in severe preeclampsia-eclampsia. Am. J. Obstet. Gynecol. 155, 501-506 (1986).
23. Plouin, P.F., Chatellier, G., Guyenne, T.T., Vincent, N. & Corvol, P. Recent advances in the clinical study of the renin system. Reference values and conditions of validity. Presse Med. 18, 917-921 (1989).