Age‐Dependent Striatal Excitotoxic Lesions Produced by the Endogenous Mitochondrial Inhibitor Malonate

Journal of Neurochemistry

Volumn 61, Issue 3, 1993, Pages 1147-1150

  Beal, M Flint ^a   Brouillet, Emmanuel ^a   Jenkins, Bruce ^b   Henshaw, Ross ^a   Rosen, Bruce ^b   Hyman, Bradley T ^a  

^a Neurology Service   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Aging; Excitotoxicity; Huntington's disease; Malonate; Mitochondria; Neurodegenerative diseases; Striatum

Indexed keywords

3 NITROPROPIONIC ACID; 4 AMINOBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; DIZOCILPINE; EXCITOTOXIN; MALONIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SUBSTANCE P; SUCCINATE DEHYDROGENASE;

AGING; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; BRAIN MITOCHONDRION; CONTROLLED STUDY; CORPUS STRIATUM; CYTOTOXICITY; ENERGY METABOLISM; ENZYME INHIBITION; HUNTINGTON CHOREA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; AGING; ANIMAL; CORPUS STRIATUM; DIZOCILPINE MALEATE; GAMMA-AMINOBUTYRIC ACID; LACTATES; LACTIC ACID; MAGNETIC RESONANCE IMAGING; MALE; MALONATES; MITOCHONDRIA; NEUROTOXINS; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSTATIN; SUBSTANCE P; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027204154     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1993.tb03633.x     Document Type: Article

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