The CR2/CD19 complex on human B cells contains the src-family kinase Lyn

International Immunology

Volumn 5, Issue 7, 1993, Pages 699-705

  Noesel, Carel J M van ^a   Lankester, Arjan C ^a   Schijndel, Gijs M W van ^a   Lier, René A W van ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

B cell receptor complex; CD19; CD21; CR2; Lyn; Protein kinase

Indexed keywords

CD19 ANTIGEN; CELL SURFACE IMMUNOGLOBULIN; COMPLEMENT COMPONENT C3D; COMPLEMENT COMPONENT C3D RECEPTOR; COMPLEMENT RECEPTOR; MONOCLONAL ANTIBODY; PROTEIN KINASE;

ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL;

ANTIGENS, CD; ANTIGENS, CD19; ANTIGENS, CD4; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; B-LYMPHOCYTES; HUMAN; PHOSPHORYLATION; PROTEIN-TYROSINE KINASE; RECEPTORS, COMPLEMENT 3D; SUPPORT, NON-U.S. GOV'T;

EID: 0027200521     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/5.7.699     Document Type: Article

References (40)

1. Nadler, L. M., Anderson, K. C., Marti, G., Bates, M., Park, E., Daley, J. F., and Schlossman, S. F. 1983. B4, a human lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes. J. Immunol. 131:244.
2. Tedder, T. F. and Isaacs, C. M. 1989. Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. J. Immunol. 143:712.
3. Zhou, L.-J., Ord, D. C., Hughes, A. L., and Tedder, T. F. 1991. Structure and domain organization of the CD19 antigen of human, mouse and guinea pig B lymphocytes. J. Immunol. 147:1424.
4. van Noesel, C. J. M., Brouns, G. S., van Schijndel, G. M. W., Bende, R. J., Mason, D. Y., Borst, J., and van Lier, R. A. W. 1992. Comparison of human B cell antigen receptor complexes: Membrane-expressed forms of immunoglobulin (Ig) M, IgD, and IgG are associated with structurally related heterodimers. J. Exp. Med. 175:1511.
5. Mason, D. Y., van Noesel, C. J. M., Cordell, J. L., Comans-Bitter, W. M., Micklem, K., Tse, A. G. D., van Lier, R. A. W., and van Dongen, J. J. M. 1992. The B29 and mb-1 polypeptides are differentially expressed during human B cell differentiation. Eur. J. Immunol. 22:2753.
6. Anderson, K. C., Bates, M. P., Slaughenhoupt, B. L., Pinkus, G. S., Schlossman, S. F., and Nadler, L. M. 1984. Expression of human B cell-associated antigens on leukemias and lymphomas: a model of human B cell differentiation. Stood 63:1424.
7. van Noesel, C. J. M., Lankester, A. C., and van Lier, R. A. W. 1993. Dual antigen recognition by B cells. Immunol. Today 14:8.
8. Matsumoto, A. K., Kopicky-Burd, J., Carter, R. H., Tuveson, D. A., Tedder, T. F., and Fearon, D. T. 1991. Intersection of the complement and immune system: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19. J. Exp. Med. 173:55.
9. Bradbury, L. E., Kansas, G. S., Levy, S., Evans, R. L., and Tedder, T. F. 1992. CD19/CD21 signal transduction complex of human B lymphocytes includes the TAPA-1 and Leu-13 molecules J. Immunol. 149:2841.
10. Pesando, J. M., Bouchard, L. S., and McMaster, B. E. 1989. CD19 is functionally and physically associated with surface immunoglobulin. J. Exp. Med. 170:2159.
11. Tanner, J., Weis, J., Fearon, D., Whang, Y., and Kieff, E. 1987. Epstein-Barr Virus gp350/220 binding to the B lymphocyte C3d receptor mediates adsorption, capping and endocytosis. Cell 50:203.
12. Pezzutto, A., Dorken, B., Rabinovitch, P. S., Ledbetter, J. A., Moldenhauer, G., and Clark, E. A. 1987. CD19 monoclonal antibody HD37 inhibits anti-immunoglobulin-induced B cell activation and proliferation. J. Immunol. 138:2793.
13. De Rie, M. A., Schumacher, T. N. M., van Schijndel, G. M. W., van Lier, R. A W, and Miedema, F. 1989. Regulatory role of CD19 molecules in B-cell activation and differentiation. Cell. Immunol. 118:368.
14. Ledbetter, J. A., Rabinovitch, P. S., June, C. H., Song, C. W., Clark, E. A., and Uckun, F. M. 1988. Antigen-independent regulation of cytoplasmic calcium in B cells with a 12-kDa B-cell growth factor and anti-CD19. Proc. Natl Acad. Sci. USA 85:1897.
15. Smith, S. H., Ftigley, K. P., and Callard, R. E. 1991. Activation of human B cells through the CD19 surface antigen results in homotypic adhesion by LFA-1-dependent and -pendent mechanisms. Immunology 73:293.
16. Ullrich, A. and Schlessinger, J. 1990. Signal transduction by receptors with tyrosine kinase activity. Cell 61:203.
17. Klausner, R. D. and Samelson, L. E. 1991. T cell antigen receptor activation pathways: The tyrosine kinase connection. Cell 64:875.
18. Moore, M. D., Cooper, N. R., Tack, B. T., and Nemerow, G. R. 1987. Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes. Proc. Natl Acad. Sci. USA 84:9194.
19. Weis, J. J., Toothaker, L. E., Smith, J. A., Weis, J. H., and Fearon, D. T. 1988. Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins. J. Exp. Med. 167:1047.
20. Mason, D. Y., Cordell, J. L., Tse, A. G. D., van Dongen, J. J. M., van Noesel, C. J. M., Micklem, K., Pulford, K. A. F., Valensi, F., Comans-Bitter, W. M., Borst, J., and Gatter, K. C. 1991. The IgM-assodated protein mb-1 as a marker of normal and neoplastic B cells. J. Immunol. 147:2474.
21. ck. Mot. Cell. Biol. 7:237.
22. Cooper, J. A., Esch, F. S., Taylor, S. S., and Hunter, T. 1984. Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases In vivo and in vitro. J. Biol. Chem. 259:7835.
23. O’Farrell, P. H. 1975. High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250:4007.
24. Cleveland, D. W., Fischer, S. G., Kirschner, M. W., and Laemmli, U. K. 1977. Peptide mapping by limited proteolysis in sodium dodecyt sulfate and analysis by gel electrophoresis. J. Biol. Chem. 252:1102.
25. Cooper, J. A., Sefton, B. M., and Hunter, T. 1983. Detection and qualification of phosphotyrosine in protein. Methods Enzymol. 99:387.
26. Samelson, L. E., Phillips, A. F., Luong, E. T., and Klausner, R. D. 1990. Assodation of the fyn protein-tyrosine kinase with the T-cell antigen receptor. Proc. Nati Acad. Sci. USA 87:4358.
27. Yamanashi, Y., Kakiuchi, T., Mizuguchi, J., Yamamoto, T., and Toyoshima, K. 1991. Assodation of B cell antigen receptor with protein tyrosine kinase. Lyn. Science 251:192.
28. Veillette, A., Bookman, M. A., Horak, E. M., and Bolen, J. B. 1988. The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase P5611*. Cell 55:301.
29. Hatakeyama, M., Kono, T., Kobayashi, N., Kawahara, A, Levin, S. D., Perlmutter, R. M., and Taniguchi, T. 1991. Interaction of the IL-2 receptor with the src-family kinase p56**: Identification of novel intermolecular assodation. Science 252:1523.
30. Eiseman, E. and Bolen, J. B. 1992. Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases. Nature 355:78.
31. Rudd, C. E. 1990. CD4, CD8 and the TCR-CD3 complex: a novel dass of protein-tyrosine kinase receptor. Immunol. Today 11:400.
32. Yi, T., Bolen, J. B., and Ihle, J. N. 1991. Hematopoetic cells express two forms of lyn kinase differing by 21 amino adds in the amino terminus. Mol. Cell. Biol. 11:2391.
33. Stanley, E., Ralph, S., McEwen, S., Boulet, I., Holtzman, D. A., Lock, P., and Dunn, A. R. 1991. Alternatively spliced murine lyn mRNAs encode distinct proteins. Mol. Cell. Biol. 11:3399.
34. Clark, M. R., Campbell, K. S., Kazlauskas, A., Johnson, S. A., Hertz, M., Potter, T. A., Pleiman, C., and Cambier, J. C. 1992. The B cell antigen receptor complex: association of lg- a and lg-/3 with distinct cytoplasmic effectors. Science 258:123.
35. Burgess, K. E., Odysseos, A. D., Zalvan, C., Druker, B. J., Anderson, P., Schlossman, S. F., and Rudd, C. E. 1991. Biochemical identification of a direct physical interaction between the CD4: p56** and T(TcR)/CD3 complexes. Eur. J. Immunol. 21:1663.
36. Reth, M., Hombach, J., Wienands, J., Campbell, K. S., Chien, N., Justement L B., and Cambier, J. C. 1991. The B-cell antigen receptor complex. Immunol. Today 12:196.
37. Venkitaraman, A. R., Williams, G. T., Darlavach, P., and Neuberger, M. S. 1991. The B-cell antigen receptor of the five immunoglobulin classes. Nature 352:777.
38. van Noesel, C. J. M., Borst, J., De Vries, E. F. R., and van Lier, R. A. W. 1990. Identification of two distinct phosphoproteins as components of the human B cell antigen receptor complex. Eur. J. Immunol. 20:2789.
39. van Noesel, C. J. M., van Lier, R. A. W., Cordell, J. L., Tse, A. G. D., van Schijndel, G. M. W., De Vries, E. F. Ft., Mason, D. Y., and Borst J. 1991. The membrane IgM-assodated heterodimer on human B cells is a newly defined B cell antigen that contains the protein product of the mb-1 gene. J. Immunol. 146:3881.
40. Carter, R. H. and Fearon, D. T. 1992. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 256:105.