Tumor necrosis factor-α blockade prevents neutrophil CD18 receptor upregulation and attenuates acute lung injury in porcine sepsis without inhibition of neutrophil oxygen radical generation

Journal of Clinical Investigation

Volumn 91, Issue 4, 1993, Pages 1459-1468

  Windsor, A C J ^a   Walsh, C J ^a   Mullen, P G ^a   Cook, D J ^a   Fisher, B J ^a   Blocher, C R ^a   Leeper Woodford, S K ^a   Sugerman, H J ^a   Fowler III, A A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

cytokines; neutrophil; septic lung injury; 2 integrins

Indexed keywords

CD11 ANTIGEN; CD18 ANTIGEN; MONOCLONAL ANTIBODY; MYELOPEROXIDASE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GRAM NEGATIVE SEPSIS; HEMODYNAMICS; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE COUNT; LEUKOCYTE MIGRATION; LUNG INJURY; LUNG LAVAGE; LUNG SEQUESTRATION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; RECEPTOR UPREGULATION; SWINE;

EID: 0027196141     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116351     Document Type: Article

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