Role of aminopeptidase N (CD13) in tumor‐cell invasion and extracellular matrix degradation

International Journal of Cancer

Volumn 54, Issue 1, 1993, Pages 137-143

  Saiki, Ikuo ^a   Yoneda, Junya ^a   Azuma, Ichiro ^a   Fujii, Hideji ^b   Abe, Fuminori ^b   Nakajima, Motowo ^c   Tsuruo, Takashi ^c  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NIPPON KAYAKU CO LTD   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSOMAL AMINOPEPTIDASE;

ARTICLE; CELL INVASION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR CELL;

AMINOPEPTIDASES; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD13; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL ADHESION; CELL MOVEMENT; EXTRACELLULAR MATRIX; HUMAN; IN VITRO; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

EID: 0027195127     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.2910540122     Document Type: Article

References (31)

1. Neutral surface aminopeptidase activity of human tumor cell lines
2. Metalloproteinase activity of CD13/ aminopeptidase N on the surface of human myeloid cells
3. Restoration of impaired immune functions of aged animals by chronic bestatin treatment
4. Metastatic mammary adenocarcinoma cell lines expressed elevated levels of plasma membrane cathepsin H‐like and aminopeptidase‐like activities
5. Aminopeptidase N is a major receptor for the entropathogenic coronavirus TGEV
6. The biology of cancer invasion and metastases
7. Characterization of the neutral aminopeptidase activity associated to the mouse thymocyte‐activating molecules
8. Action of ubenimex on aminopeptidase activities in spleen cells and peritoneal macrophages from mice
9. Preferential digestion of membrane collagen by an enzyme derived from metastatic tumor
10. Effect of plasminogen activator (urokinasc), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane
11. Tumor invasion and the extracellular matrix
12. Metastatic potential correlates with enzymatic degradation of basement‐membrane collagen
13. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase
14. The role of cell‐adhesion proteins—laminin and fibronectin—in the movement of malignant and metastatic cells
15. Changes in macrophages ectoenzymes associated with anti‐tumor activity
16. Membrane and matrix localization of proteinases—a common theme in tumor‐cell invasion and angiogenesis
17. Differences in chemotaxis to fibronectin in low‐ and high‐metastatic tumor cells
18. In vivo selection of human renal‐cell carcinoma cells with high metastatic potential in nude mice
19. Tumor invasion and extracellular matrix degradative enzymes: regulation of activity by organ factors
20. Degradation of basement‐membrane type‐IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clone of differing metastatic potentials
21. Tumor‐cell instability, diversification, and progression to the metastatic phenotype' from oncogene to oncofetal expression
22. Metastatic tumor‐cell interactions with endothelium, basement membrane and tissue
23. Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequence of cell‐adhesive molecules
24. Inhibition of tumor‐cell invasion by ubenimex (bestatin) in vitro
25. Stimulatory effect of bestatin, a new specific inhibitor of aminopeptidase, on the blastogenesis of guinea‐pig lymphocytes
26. The ability of the immunomodulating dipeptide bestatin to activate cytotoxic mono‐nuclear phagocytes
27. Immunomodulatory and therapeutic properties of bestatin in mice
28. Proteolytic degradation of extracellular matrix in tumor invasion
29. Aminopeptidase as a marker for macrophage differentiation
30. Human aminopeptidase N is a receptor for human coronavirus 229E
31. Inhibition of tumor invasion and extracellular matrix degradation by ubenimex (bestatin)