Conformational change of plasminogen: Effects of N-Terminal peptides of Glu-plasminogen

Thrombosis Research

Volumn 70, Issue 2, 1993, Pages 151-159

  Takada, Yumiko ^a   Urano, Tetsumei ^a   Takada, Akikazu ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

euglobulin clot lysis; N terminal peptides; plasminogen; tissue plasminogen activator; urinary plasminogen activator

Indexed keywords

ENDOGENOUS COMPOUND; PLASMINOGEN; TISSUE PLASMINOGEN ACTIVATOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATION; PRIORITY JOURNAL; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; COMPARATIVE STUDY; FIBRINOLYSIS; HUMAN; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PLASMINOGEN; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; TISSUE PLASMINOGEN ACTIVATOR; URINARY PLASMINOGEN ACTIVATOR;

EID: 0027193213     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/0049-3848(93)90156-I     Document Type: Article

References (12)

1. Molecular mechanism of physiological fibrinolysis
2. Localization of individual lysine-binding regions in human plasminogen and investigations on their complex-forming properties
3. A monoclonal antibody to the ε-aminocaproic acid binding site on the kringle 4 region of human plasminogen that accelerates the activation of Glul-plasminogen by urokinase
4. The AH-site of plasminogen and two C-terminal fragments: A weak lysine-binding site preferring ligands not carrying a free carboxylate functions
5. The effects of α-, ω-aminoacids on human plasminogen structure and activation
6. Fluorescence spectrophotometric studies on the conformational changes induced by w-aminoacids in two isozymes of Glu-plasminogen (I and II)
7. Studies on the conformational changes of plasminogen induced during activation to plasmin by 6-aminohexanoic acid
8. Structural relationship between “glutamic acid” and “lysine” forms of human plasminogen and their interaction with the NH2-terminal activation peptides as studied by affinity chromatography
9. Effects of N-terminal peptide of Glu-plasminogen on the activation of Glu-plasminogen and its conversion to Lys-plasminogen
10. Plasminogen: purification from human plasma by affinity chromatography
11. Effects of fibrinogen and fibrin on the activation of Glu- and Lys-plasminogen by urokinase
12. Cleavage of structural proteins during the assembly of the head of bacteriophage T4