Stable Expression of Human Cytochrome P4502E1 in HepG2 Cells: Characterization of Catalytic Activities and Production of Reactive Oxygen Intermediates

Biochemistry

Volumn 32, Issue 27, 1993, Pages 6928-6937

  Dai, Yan ^a   Rashba Step, Julia ^a   Cederbaum, Arthur I ^a  

^a Mount Sinai University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLPYRAZOLE; 4 NITROPHENOL; ADENOSINE TRIPHOSPHATE; ALCOHOL; ANILINE; CATALASE; COMPLEMENTARY DNA; CYTOCHROME P450; DIMETHYLNITROSAMINE; FERRIC ION; GALLIC ACID PROPYL ESTER; GLUTATHIONE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN G ANTIBODY; MALONALDEHYDE; MICONAZOLE; PARAQUAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID; TROLOX C; VIRUS DNA; VIRUS RNA; ZALCITABINE;

ARTICLE; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME ASSAY; HEPATOMA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIPID PEROXIDATION; LIVER MICROSOME; MOLECULAR CLONING; NORTHERN BLOTTING; PRIORITY JOURNAL; RESTRICTION MAPPING; RETROVIRUS; SOUTHERN BLOTTING; VIRUS INFECTION;

3T3 CELLS; ANIMAL; BLOTTING, NORTHERN; CATALYSIS; CLONING, MOLECULAR; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DNA; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMAN; ISOENZYMES; LIPID PEROXIDATION; LIVER; MICE; MICROSOMES, LIVER; OXIDATION-REDUCTION; OXIDOREDUCTASES, N-DEMETHYLATING; REACTIVE OXYGEN SPECIES; RNA; SUPPORT, U.S. GOV'T, P.H.S.; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0027185531     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00078a017     Document Type: Article

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