Differential CD4 T Cell Activation in Measles

Journal of Infectious Diseases

Volumn 168, Issue 2, 1993, Pages 275-281

  Griffin, Diane E ^a,b   Ward, Brian J ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; MITOGENIC AGENT; MONOCLONAL ANTIBODY CD3;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MALE; MEASLES; MONONUCLEAR CELL; PRIORITY JOURNAL; RASH; SKIN TEST; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; DISEASE OUTBREAKS; FEMALE; HUMAN; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MALE; MARYLAND; MEASLES; PENNSYLVANIA; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027183947     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/168.2.275     Document Type: Article

References (73)

1. Miller DL. Frequency of complications of measles, 1963. Br Med J 1964; 2: 75-8.
2. Aaby P, Bukh J, Kronborg D, Lisse JM, daSilva ME. Delayed excess mortality after exposure to measles during the first six months oflife. Am J Epidemiol 1990; 132: 211-9.
3. Tamashiro VG, Perez HH, Griffin DE. Prospective study of the magnitude and duration ofchanges in tuberculin reactivity during complicated and uncomplicated measles. Pediatr Infect Dis J 1987; 6: 451-4.
4. Von Pirquet C. Verhalten der kutanen tuberkulin-reaktion wahrend der Masern. Deutsch Med Wochenschr 1908; 34: 1297-1300.
5. Griffin DE, Ward BJ, Jauregui E, Johnson RT, Vaisberg A. Natural killer cell activity during measles. Clin Exp Immunol 1990; 81: 218-24.
6. Griffin DE, Cooper SJ, Hirsch RL, Changes in plasma IgE levels during complicated and uncomplicated measles virus infections. J Allergy Clin Immunol 1985; 76: 206-13.
7. Hirsch RL, Griffin DE, Johnson RT, Cellular immune responses during complicated and uncomplicated measles virus infections of man. Clin Immunol Immunopathol 1984; 31: 1-12.
8. Finkel A, Dent PB. Abnormalities in lymphocyte proliferation in classical and atypical measles infection. Cell Immunol 1973; 6: 41-8.
9. Ward BJ, Johnson RT, Vaisberg A, Jauregui E, Griffin DE. Cytokine production in vitro and the Iymphoproliferative defect of natural measles virus infection. Clin Immunol Immunopathol 1991; 61: 23648.
10. Ward BJ, Johnson RT, Vaisberg A, Jauregui E, Griffin DE. Spontaneous proliferation of peripheral mononuclear cells in natural measles virus infection: Identification of dividing cells and correlation with mitogen responsiveness. Clin Immunol Immunopathol 1990; 55: 315-26.
11. Griffin DE, Moench TR, Johnson RT, Lindo de Soriano I, Vaisberg A. Peripheral blood mononuclear cells during natural measles virus infection: Cell surface phenotypes and evidence for activation. Clin Immunol Immunopathol 1986; 40: 305-12.
12. Griffin DE, Ward BJ, Jauregui E, Johnson RJ, Vaisberg A. Immune activation during measles: Interferon-ϒ, and neopterin in plasma and cerebrospinal fluid in complicated and uncomplicated disease. J Infect Dis 1990; 161: 449-53.
13. Griffin DE, Ward BJ, Jauregui E, Johnson RT, Vaisberg A. Immune activation during measles. N Engl J Med 1989; 320: 1667-72.
14. Griffin DE, Ward BJ, Jauregui E, Johnson RT, Vaisberg A. Immune activation during measles:. B2-microglobulin in plasma and cerebrospinal fluid in complicated and uncomplicated disease. J Infect Dis 1992; 166: 1170-3.
15. Van Binnendijk RS, Poelen MCM, Kuijpers KC, Osterhaus ADME, Uytdehaag FGCM. The predominance ofCD8+ T cells after infection with measles virus suggests a role for CD8+ class I MHCrestricted cytotoxic T lymphocytes (CTL) in recovery from measles. J Immunol 1990; 144: 2394-9.
16. Kimura A, Tosaka K, Nakao T. Measles rash. I. Light and electron microscopic study of skin eruptions. Arch Virol 1975; 47: 295-307.
17. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of Iymphokine activities and secreted proteins. J Immunol 1986; 136: 2348-57.
18. Del Prete GF, De Carli M, Mastromauro C, Purified protein derivative ofMycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type I T helper or type 2 T helper) profiles of cytokine production. J Clin Invest 1991; 88: 346-50.
19. Salgame P, Abrams JS, Clayberger C, Differing Iymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science 1991; 254: 279-82.
20. Peltz G. A role of CD4+ T-cell subsets producing a selective pattern of Iymphokines in the pathogenesis of human chronic inflammatory and allergic diseases. Immunol Rev 1991; 123: 23-35.
21. Kapsenberg ML, Wierenga EA, Bos JD, Jansen HM. Functional subsets of allergen-reactive human CD4+ T cells. Immunol Today 1991; 12: 392-5.
22. Yamamura M, Uyemura K, Deans RJ, Defining protective responses to pathogens: Cytokine profiles in leprosy lesions. Science 1991; 254: 277-9.
23. Mosmann TR. Cytokine secretion patterns and cross-regulation of T cell subsets. Immunol Res 1991; 10: 183-8.
24. Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A. Downregulation of Th I cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med 1991; 173: 159-66.
25. Gajewski TF, Fitch FW. Anti-proliferative effect oflFN-gamma in immune regulation I. IFN-gamma inhibits the proliferation ofTh2 but not Th I murine helper T lymphocyte clones. J Immunol 1988; 140: 4245-52.
26. Fiorentino OF, Bond MW, Mosmann TR. Two types of mouse T helper cell IV. Th2 clones secrete a factor that inhibits cytokine production by Thl clones. J Exp Med 1989; 170: 2081-95.
27. Fiorentino OF, Zlotnik A, Vieira P, IL-I 0 acts on the antigen-presenting cell to inhibit cytokine production by Th I cells. J Immunol 1991; 146: 3444-51.
28. Ward BJ, Griffin DE. Changes in cytokine production after measles virus vaccination: Predominant production of IL-4 suggests induction ofa Th2 response. Clin Immunol Immunopathol 1993; 67: 171-7.
29. Martinez OM, Gibbons RS, Garovoy MR, Aronson FR. IL-4 inhibits IL-2 receptor expression and IL-2 dependent proliferation of human T cells. J Immunol 1990; 144: 2211-5.
30. Bello-Fernandez C, Oblakowski P, Meager A, IL-4 acts as a homeostatic regulator of IL-2-induced TNF and IFN-gamma. Immunology 1991; 72: 161-6.
31. Hus DH, Moore KW, Spits H. Differential effects oflL-4 and IL-IO on IL-2-induced IFN-gamma synthesis and Iymphokine-activated killer activity. Int Immunol 1992; 4: 563-9.
32. Ehlers S, Smith KA. Differentiation ofT celllymphokine gene expression: The in vitro acquisition of T cell memory. J Exp Med 1991; 173: 25-36.
33. Lewis DB, Yu CC, Meyer J, English BK, Kahn SJ, Wilson CB. Cellular and molecular mechanisms for reduced interleukin 4 and interferongamma production by neonatal T cells. J Clin Invest 1991; 87: 194-202.
34. Kurane I, Innis BL, Nimmannitya S, Activation ofT lymphocytes in dengue virus infections: High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue. J Clin Invest 1991; 88: 1473-80.
35. Peakman M, Senaldi G, Foote N, McManus TJ, Vergani D. Naturally occurring soluble CD4 in patients with human immunodeficiency virus infection. J Infect Dis 1992; 165: 799-804.
36. Moench TR, Griffin DE, Obriecht CR, Vaisberg AJ, Johnson RT. Acute measles in patients with and without neurological involvement: Distribution of measles virus antigen and RNA. J Infect Dis 1988; 158: 433-42.
37. Hyypia T, Korkiamaki P, Vainionpaa R. Replication ofmeasles virus in human lymphocytes. J Exp Med 1985; 161: 1261-71.
38. Gottlieb OJ, Prentice HG, Heslop HE, Bello C, Brenner MK. IL-2 infusion abrogates humoral immune responses in humans. Clin Exp Immunol 1992; 87: 493-8.
39. Swain SL, McKenzie DT, Weinberg AD, Hancock W. Characterization ofT helper I and 2 cell subsets in normal mice: Helper T cells responsible for IL-4 and IL-5 production are present as precursors that require priming before they develop into Iymphokine-secreting cells. J Immunol 1988; 141: 3445-55.
40. Fong TAT, Mosmann TR. Alloreactive murine CD8+ T cell clones secrete the Th I pattern ofcytokines. J Immunol 1990; 144: 1744-52.
41. Gazzinelli RT, Makino M, Chattopadhyay SK, CD4+ subset regulation in viral infection: Preferential activation ofTh2 cells during progression of retrovirus-induced immunodeficiency in mice. J Immunol 1992; 148: 182-8.
42. Niemialtowski MG, Rouse BT. Predominance of Th I cells in ocular tissues during herpetic stromal keratitis. J Immunol1992; 149: 30359.
43. Chatelain R, Varkila K, Coffman RL. IL-4 induces a Th2 response in Leishmania major-infected mice. J Immunol 1992; 148: 1182-7.
44. Heinzel FP, Sadick MD, Holaday BJ, Coffman RL, Locksley RM. Reciprocal expression of interferon-gamma or interleukin 4 during the resolution or progression of murine leishmaniasis: Evidence for distinct helper T cell subsets. J Exp Med 1989; 169: 59-72.
45. Gazzinelli RT, Hakim FT, Hieny S, Shearer GM, Sher A. Synergistic role of CD4+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J Immunol 1991; 146: 286-92.
46. Sadick MD, Heinzel FP, Shigekane VM, Fisher WL, Locksley RM. Cellular and humoral immunity to Leishmania major in genetically susceptible mice after in vivo depletion ofL3T4+ T cells. J Immunol 1987; 139: 1303-9.
47. Grzych JM, Pearce E, Cheever A. Egg deposition is the major stimulus for the production ofTh2 cytokines in murine schistosomiasis mansoni. J Immunol 1991; 146: 1322-7.
48. Nelson JD, Sandusky G, Peck FB. Measles skin test and serologic response to intradermal measles antigen. JAMA 1966; 198: 185-6.
49. Greenstein JI, McFarland HF. Response of human lymphocytes to measles virus after natural infection. Infect Immun 1983; 40: 198-204.
50. McFarland HF, McFarlin DE. Cellular immune response to measles, mumps, and vaccinia viruses in multiple sclerosis. Ann Neurol 1979; 6: 101-6.
51. Jabara HH, Ahern DJ, Vercelli D, Geha RS. Hydrocortisone and IL-4 induce IgE isotype switching in human B cells. J Immunol 1991; 147: 1557-60.
52. Mathiesen T, Hammarstrom L, Fridell E. Aberrant IgG subclass distribution to measles in healthy seropositive individuals, in patients with SSPE and in immunoglobulin-deficient patients. Clin Exp Immunol 1990; 80: 202-5.
53. Nagler A, Lanier LL, Phillips JH. The effects oflL-4 on human natural killer cells: A potent regulator of IL-2 activation and proliferation. J Immunol 1988; 141: 2349-51.
54. Gautam SC, Chikkala NF, Hamilton TA. Anti-inflammatory action of IL-4: Negative regulation of contact sensitivity to trinitrochlorobenzene. J Immunol 1992; 148: 1411-5.
55. Kawakami Y, Custer MC, Rosenberg SA, Lotze MT. IL-4 regulates IL-2 induction of Iymphokine-activated killer activity from human lymphocytes. J Immunol 1989; 142: 3452-61.
56. Abramson SL, Gallin JI. IL-4 inhibits superoxide production by human mononuclear phagocytes. J Immunol 1990; 144: 625-30.
57. Donnelly RP, Fenton MJ, Kaufman JO, Gerrard TL. IL-I expression in human monocytes is transcriptionally and posttranscriptionally regulated by IL-4. J Immunol 1991; 146: 3431-6.
58. Hart PH, Vitti GF, Burgess DR, Whitty GA, Piccoli OS. Potential antiinflammatory effects ofinterleukin 4: Suppression ofhuman monocyte tumor necrosis factor alpha, interleukin I, and prostaglandin E2. Proc Natl Acad Sci USA 1989; 86: 3803-7.
59. Essner R, Rhoades K, McBride WH, Morton DL, Economou JS. IL-4 down-regulates IL-I and TNF gene expression in human monocytes. J Immunol 1989; 142: 3857-61.
60. Gobi AE, Aim GV. Interleukin-gamma down-regulates Sendai virusinduced production of interferon-alpha and-beta in human peripheral blood monocytes in vitro. Scand J Immunol 1992; 35: 167-75.
61. Wong HL, Welch GR, Brandes ME, Wahl SM. IL-4 antagonizes induction of Fc-gamma-RIII (CD16) expression by transforming growth factor-beta on human monocytes. J Immunol 1991; 147: 1843-8.
62. te Velde AA, Huijbens RJF, de Vries JE, Figdor CG. IL-4 decreases Fc-gamma-R membrane expression and Fc-gamma-R-mediated cytotoxic activity of human monocytes. J Immunol 1990; 144: 304-651.
63. Wong HL, Lotze MT, Wahl LM, Wahl SM. Administration ofrecombinant IL-4 to humans regulates gene expression, phenotype, and function in circulating monocytes. J Immunol 1992; 148: 2118-25.
64. Lehn M, Weiser WY, Engelhorn S, Gillis S, Remold HG. IL-4 inhibits H20 2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-gamma. J Immunol 1989; 143: 3020-4.
65. Ho JL, He SH, Rios MJC, Wick EA. Interleukin-4 inhibits human macrophage activation by tumor necrosis factor, granulocyte-monocyte colony-stimulating factor, and interleukin-3 for antileishmanial activity and oxidative burst capacity. J Infect Dis 1992; 165: 344-51.
66. Gazzinelli RT, Oswald IP, James SL, Sher A. IL-IO inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages. J Immunol 1992; 148: 1792-6.
67. Malefyt R, Haanen J, Spits H, Interleukin JO. (IL-IO) and viral IL-IO strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity ofmonocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991; 174: 915-24.
68. Taga K, Tosato G. IL-IO inhibits human T cell proliferation and IL-2 production. J Immunol 1992; 148: 1143-8.
69. Weaver CT, Hawrylowicz CM, Unanue ER. T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells. Proc Natl Acad Sci USA 1988; 85: 8181-5.
70. Joseph BS, Lampert PW, Oldstone MBA. Replication and persistence of measles virus in defined subpopulations of human leukocytes. J Virol 1975; 16: 1638-49.
71. Sullivan JL, Barry DW, Lucas SJ, Albrecht P. Measles infection of human mononuclear cells. I. Acute infection of peripheral blood lymphocytes and monocytes. J Exp Med 1975; 142: 773-84.
72. Jiang XL, Dillehay DL, Everson MP, Tilden AB, Lamon EW. Potentiation oflL-2-induced T-cell proliferation by retinoids. Int J Immunopharmacol 1992; 14: 195-204.
73. Salonen R, Ilonen J, Salmi A. Measles virus infection of unstimulated blood mononuclear cells in vitro: Antigen expression and virus production preferentially in monocytes. Clin Exp Immunol 1988; 71: 224-8.