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Volumn 3, Issue 8, 1993, Pages 1609-1614

A concise enantioselective synthesis of rans-olefin dipeptide isosteres

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE; ANTIVIRUS AGENT; DIPEPTIDE; PROTEINASE INHIBITOR;

ARTICLE; ENANTIOMER; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; PEPTIDE SYNTHESIS; STEREOCHEMISTRY;

EID: 0027182793 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)80027-X Document Type: Article

Times cited : (34)

References (24)

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- Spatola¹

3
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4
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8
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- Panek¹ Yang²

11
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- (1991) J. Am. Chem. Soc. , vol.113 , pp. 9868-9870
- Panek¹ Yang²

12
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- Panek¹ Yang² Muler³

14
- 0001685865
- Synthesis of the chiral silane reagents:
- (1991) J. Org. Chem. , vol.56 , pp. 3431-3438
- Sparks¹ Panek²

15
- 0000095354
- (1991) J. Org. Chem. , vol.56 , pp. 7341-7344
- Panek¹ Beresis² Xu³ Yang⁴

16
- 0000397735
- Silane 1f was prepared by an analogous Claisen strategy procedure starting from 4-methyl-1-pentyn-3-ol.
- (1993) J. Org. Chem. , vol.58 , pp. 1003-1010
- Panek¹ Yang² Solomon³

17
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- (1982) J. Am. Chem. Soc. , vol.104 , pp. 4962-4965
- Hayashi¹ Konishi² Ito³ Kumada⁴

18
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- E′ addition for the syn or anti-2, 5 substitution on the derived homallylic alcohols. These assignments are based on the fact that the C2-stereocenter of the E-crotylsilanes 1 does not show any appreciable signs of epimerization under the described reaction condition. As [[Truncated]]

19
- 85005617766
- Concerning the Stereochemistry of SE'-Type Reactions
- E′-type reactions see, andreferences cited therein.
- (1989) Israel Journal of Chemistry , vol.29 , pp. 321-343
- Matassa¹ Jenkins² Kumin³ Damm⁴ Schreiber⁵ Felix⁶ Zass⁷ Eschenmoser⁸

20
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- (1982) J. Am. Chem. Soc. , vol.104 , pp. 4962-4963
- Hayashi¹ Konishi² Ito³ Kumada⁴

21
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- (1989) Tetrahedron , vol.45 , pp. 1053-1065
- Denmark¹ Weber² Wilson³ Willson⁴

23
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- 5 did promote the reaction producing the desired homoallylic alcohol in low yield.

24
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- 2O. To each assay tube 4μL of a DMSO solution containing the inhibitor (or neat DMSO for the control reaction) and the tubes left at room temperature for 15 minutes prior to initiating the enzyme reaction. The reactions were initiated by adding 20mL of HIV substrte (0.5 mM, Bachem) and the tubes incubated at 37 °C. After 30 minutes, the reactions were quenched with 60 mL of 20% trifluoroacetic acid, before being transfered to the [[Truncated]]

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.