Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts critical role of the AT1 receptor subtype

Circulation Research

Volumn 73, Issue 3, 1993, Pages 413-423

  Sadoshima, Jun Ichi ^b   Izumo, Seigo ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b NONE

Author keywords

Angiotensin II; AT1 receptor; Hypertrophy; Immediate early genes; Mitogenesis

Indexed keywords

ALPHA ACTIN; ANGIOTENSIN; ANGIOTENSIN ANTAGONIST; ANGIOTENSIN RECEPTOR; ANGIOTENSINOGEN; ATRIAL NATRIURETIC FACTOR; RECEPTOR SUBTYPE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL HYPERPLASIA; CONTROLLED STUDY; DNA SYNTHESIS; FIBROBLAST; GENE INDUCTION; HEART HYPERTROPHY; HEART MUSCLE CELL; HORMONE ACTION; IMMEDIATE EARLY GENE; IN VITRO STUDY; MITOGENESIS; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

ANGIOTENSIN II; ANGIOTENSINOGEN; ANIMAL; CARDIOMEGALY; CELLS, CULTURED; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, FOS; HYPERPLASIA; MYOCARDIUM; RATS; RECEPTORS, ANGIOTENSIN; SUPPORT, NON-U.S. GOV'T; TRANSFORMING GROWTH FACTOR BETA;

EID: 0027182438     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.73.3.413     Document Type: Article

References (55)

1. Robertson JIS, Nicholls MG, eds. The Renin-Angiotensin System. London, England: Gower Medical Publishing; 1993.
2. Garrison JC, Peach MJ. Renin and angiotensin. In: Gilman AG, Rail TW, Nies AS, Taylor P, eds. The Pharmacological Basis of Therapeutics. Elmsford, NY: Pergamon Press, Inc; 1990:749-763.
3. Mizuno K, Nakamaru M, Hiashimori K, Inagami T. Local generation and release of angiotensin II in peripheral vascular tissue. Hypertension. 1988;11:223-229.
4. Baker KM, Booz GW, Dostal DE. Cardiac actions of angiotensin II: role of an intracardiac renin-angiotensin system. Annu Rev Physiol. 1992;54:227-241.
5. Dzau VJ, Pratt RE. Cardiac, vascular and intrarenal renin angiotensin system in normal physiology and disease. In: Robertson JIS, Nicholls MG, eds. The Renin-Angiotensin System. London, England: Gower Medical Publishing; 1993:42.1-42.8.
6. Lindpaintner K, Ganten D. The cardiac renin-angiotensin system: an appraisal of present experimental and clinical evidence. Circ Res. 1991;68:905-921.
7. Wolf G, Nelson EG. Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. Am J Physiol. 1990;259: F768-F777.
8. Geisterfer AAT, Peach MJ, Owens GK. Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ Res. 1988;62:749-756.
9. Berk BC, Vekshtein V, Gordon HM, Tsuda T. Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells. Hypertension. 1989;13:305-314.
10. Owens GK. Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells. Am J Physiol. 1989;257:H1755-H1765.
11. Paquet J-L, Baudouin-Legros M, Brunelle G, Meyer P. Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats. J Hypertens. 1990;8:565-572.
12. Dubey RK, Roy A, Overbeck HW. Culture of renal arteriolar smooth muscle cells: mitogenic responses to angiotensin II. Circ Res. 1992;71:1143-1152.
13. Khairallah PA, Kanabus J. Angiotensin and myocardial protein synthesis. Perspect Cardiovasc Res. 1983;8:337-347.
14. Linz W, Schoelkens BA, Ganten D. Converting enzyme inhibition specifically prevents the development and induces regression of cardiac hypertrophy in rats. Clin Exp Hypertens. 1989;11:1325-1350.
15. Baker KM, Aceto JF. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. Am J Physiol. 1990;259: H610-H618.
16. Beinlich CJ, White GJ, Baker KM, Morgan HE. Angiotensin II and left ventricular growth in newborn pig heart. J Mol Cell Cardiol. 1991;23:1031-1038.
17. Pfeffer MA, Lamas GA, Vaughan DE, Parisi AF, Braunwald E. Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction. N Engl J Med. 1988;319:80-86.
18. Baker KM, Chernin MI, Wixson SK, Aceto JF. Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats. Am J Physiol. 1990;259:H324-H332.
19. Zak R. Growth of the Heart in Health and Disease. New York, NY: Raven Press, Publishers; 1984.
20. Sadoshima J, Jahn L, Takahashi T, Kulik T, Izumo S. Molecular characterization of the stretch-induced adaptation of cultured cardiac cells: an in vitro model of load-induced cardiac hypertrophy. J Biol Chem. 1992;267:10551-10560.
21. Bader D, Masaki T, Fischman DA. Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J Cell Biol. 1982;95:763-770.
22. Voyta JC, Via DP, Butterfield CE, Zetter BR. Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein. J Cell Biol. 1984;99:2034-2040.
23. Ryder K, Lau LF, Nathans D. A gene activated by growth factors is related to the oncogene v-jun. Proc Natl Acad Sci USA. 1988; 85:1487-1491.
24. 1-antitrypsin genes. J Biol Chem. 1984;259:8063-8065.
25. Sporn MB, Roberts AB. Peptide Growth Factors and Their Receptors: Handbook of Experimental Pharmacology, Volume 95. New York, NY: Springer-Verlag New York, Inc; 1990.
26. 1-adrenergic response. J Clin Invest. 1983;72:732-738.
27. Iwaki K, Sukhatme VP, Shubeita HE, Chien KR. α- and β-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. J Biol Chem. 1990;265: 13809-13187.
28. Dunnmon PM, Iwaki K, Henderson SA, Sen A, Chien KR. Phorbol esters induce immediate-early genes and activate cardiac gene transcription in neonatal rat myocardial cells. J Mol Cell Cardiol. 1990;22:901-910.
29. Timmermans PBMWM, Wong PC, Chiu AT, Herblin WF. Non-peptide angiotensin II receptor antagonists. Trends Pharmacol Sci. 1991;12:55-62.
30. Izumo S, Nadal-Ginard B, Mahdavi V. Proto-oncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc Natl Acad Sci USA. 1988;85:339-343.
31. Komuro I, Kaida T, Shibasaki Y, Kurabayashi M, Katoh Y, Hoh E, Takaku F, Yazaki Y. Stretching cardiac myocytes stimulates protooncogene expression. J Biol Chem. 1990;265:3595-3598.
32. Shubeita HE, McDonough PM, Harris AN, Knowlton KU, Glembotski CC, Brown JH, Chien KR. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. J Biol Chem. 1990;265: 20555-20562.
33. Parker TG, Packer SE, Schneider MD. Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes. J Clin Invest. 1990;85:507-514.
34. Chien KR, Knowlton KU, Zhu H, Chien S. Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J. 1991;5:3037-3046.
35. Naftilan AJ, Pratt RE, Dzau VJ. Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. J Clin Invest. 1989; 83:1419-1424.
36. 2+ mobilization and protein kinase C activation. J Biol Chem. 1989;264:526-530.
37. Landschulz WH, Johnson PF, McKnight SL. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science. 1988;240:1759-1764.
38. Cao X, Koski RA, Gashler A, McKiernan M, Morris CF, Gaffney R, Hay RV, Sukhatme VP. Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol Cell Biol. 1990; 10:1931-1939.
39. Luscher B, Eisenman RN. New light on Myc and Myb, I: Myc. Genes Dev. 1990;4:2025-2035.
40. Roux P, Blanchard J-M, Fernandez A, Lamb N, Jeanteur P, Piechaczyk M. Nuclear localization of c-fos, but not v-fos proteins, is controlled by extracellular signals. Cell. 1990;63:341-351.
41. Rogers TB, Gaa ST, Allen IS. Identification and characterization of functional angiotensin II receptors on cultured heart myocytes. J Pharmacol Exp Ther. 1986;236:438-444.
42. Nakamura A, Iwao H, Fukui K, Kimura S, Tamaki T, Nakanishi S, Abe Y. Regulation of liver angiotensinogen and kidney renin mRNA levels by angiotensin II. Am J Physiol. 1990;258:E1-E6.
43. Ueno H, Perryman MD, Roberts R, Schneider MD. Differentiation of cardiac myocytes after mitogen withdrawal exhibits three sequential states of the ventricular growth response. J Cell Biol. 1988;107:1911-1918.
44. Schelling P, Ganten D, Speck G, Fischer H. Effects of angiotensin II and angiotensin II antagonist saralasin on cell growth and renin in 3T3 and SV3T3 cells. J Cell Physiol. 1979;98:503-513.
45. van Krimpen C, Smits JFM, Cleutjens JPM, Debets JJM, Schoemaker RG, Struyker HAJ, Bosman FT, Saemen MJAP. DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: effects of captopril. J Mol Cell Cardiol. 1991;23:1245-1253.
46. Weber KT, Brilla CG. Pathological hypertrophy and cardiac interstitium. Circulation. 1991;83:1849-1865.
47. Sechi LA, Griffin CA, Grady EF, Kalinyak JE, Schambelan M. Characterization of angiotensin II receptor subtypes in rat heart. Circ Res. 1992;71:1482-1489.
48. Sasaki K, Yamano Y, Bardhan S, Iwai N, Murray JJ, Hasegawa M, Matsuda Y, Inagami T. Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor. Nature. 1991;351:230-233.
49. Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE. Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor. Nature. 1991;351:233-236.
50. Fleming JW, Wisler PL, Watanabe AM. Signal transduction by G proteins in cardiac tissues. Circulation. 1992;85:420-433.
51. Cooper VG, Mercer WE, Hoober JK, Gordon PR, Kent RL, Lauva IK, Marino TA. Load regulation of the properties of adult feline cardiocytes. Circ Res. 1986;58:692-705.
52. Moalic JM, Bauters C, Himbert D, Bercovici J, Mouas C, Guicheney P, Baudoin-Legros M, Rappaport L, Emanoil-Ravier R, Mezger V. Phenylephrine, vasopressin and angiotensin II as determinants of proto-oncogene and heat-shock protein gene expression in adult rat heart and aorta. J Hypertens. 1989;7:195-201.
53. 1 receptor. Am J Hypertens. 1992;5:276-280.
54. 1 and phorbol myristate acetate on cardiac fibroblasts: regulation of fibrillar collagen mRNAs and expression of early transcription factors. Circ Res. 1991;69:483-490.
55. Gibbons GH, Pratt RE, Dzau VJ. Vascular smooth muscle cell hypertrophy vs. hyperplasia. J Clin Invest. 1992;90:456-461.