Symposium Introduction: Retrospect and prospects for neuropathy target esterase (NTE) and the delayed polyneuropathy (OPIDP) induced by some organophosphorus esters

Chemico-Biological Interactions

Volumn 87, Issue 1-3, 1993, Pages 339-346

  Johnson, M K ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Delayed neuropathy; Enzyme purification; Neuropathy target esterase; Organophosphorus compounds; Promotion; Protection

Indexed keywords

NEUROTOXIC ESTERASE; ORGANOPHOSPHATE;

CONFERENCE PAPER; DELAYED NEUROTOXICITY; HUMAN; NONHUMAN; POLYNEUROPATHY; PRIORITY JOURNAL;

ANIMAL; CARBOXYLIC ESTER HYDROLASES; ESTERS; NERVOUS SYSTEM DISEASES; ORGANOPHOSPHORUS COMPOUNDS;

EID: 0027181482     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-2797(93)90062-4     Document Type: Article

References (18)

1. Peripheral neuropathy caused by toxic agents
2. Organophosphorus compounds
3. The delayed neuropathy caused by some organophosphorus esters: mechanism and challenge
4. Organophosphorus esters causing delayed neurotoxic effects: mechanism of action and structure/activity studies
5. The target for initiation of delayed neurotoxicity by organophosphorous esters: biochemical studies and toxicological applications
6. Organophosphates and delayed neuropathy — is NTE alive and well?
7. 3H]DFP-labelled polypeptide
8. Purification and characterization of neuropathy target esterase
9. Biochemical properties and possible toxicological significance of various forms of NTE
10. The R−(+) isomer of O-n-hexyl S-methyl phosphorothioamidate causes delayed neuropathy in hens after generation of a form of inhibited neuropathy target esterase which can be reactivated ex vivo
11. Reactivation of phosphorodiamidated acetylcholinesterase and neuropathy target esterase by treatment of inhibited enzyme with potassium fluoride
12. Anomalous biochemical responses in tests of the delayed neuropathic potential of methamidophos (O,S-dimethyl phosphorothioamidate), its resolved isomers and of some higher O-alkyl homologues
13. The pathogenesis of organophosphate polyneuropathy
14. The role of neurotoxic esterase (NTE) in the prevention and potentiation of organophosphorus-induced delayed neurotoxicity (OPIDN)
15. The search for physiological functions of NTE
16. The cytoskeleton as a target for organophosphorus ester-induced delayed neurotoxicity (OPIDN)
17. Postscript to the Symposium on Organophosphorus Compound Induced Delayed Neuropathy
18. Active-site labelling and purification of nuropathy target esterase (NTE) using a biotinylated organophosphorus (OP) compound