The type of BCR/ABL junction does not predict the survival of patients with Ph1‐positive chronic myeloid leukaemia

British Journal of Haematology

Volumn 84, Issue 2, 1993, Pages 265-268

  Zaccaria, Alfonso ^a   Martinelli, Giovanni ^a   Buzzi, Marina ^a   Testoni, Nicoletta ^a   Farabegoli, Patrizia ^a   Zuffa, Eliana ^a   Zamagni, Maria Donatella ^a   Russo, Domenico ^b   Baccarani, Michele ^b   Ambrosetti, Achille ^c   Guerrasio, Angelo ^d   Saglio, Giuseppe ^d   Tura, Sante ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

^c Policlinico GB Rossi   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHRONIC MYELOID LEUKEMIA; FEMALE; GENE REARRANGEMENT; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; ONCOGENE; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; SURVIVAL;

ADOLESCENT; ADULT; AGED; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 22; FEMALE; GENES, ABL; HUMAN; LEUKEMIA, MYELOID, CHRONIC; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SUPPORT, NON-U.S. GOV'T; SURVIVAL RATE; TRANSLOCATION (GENETICS);

EID: 0027176976     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.1993.tb03062.x     Document Type: Article

References (33)

1. bcr breakpoint and prognosis of chronic phase chronic myeloid leukemia
2. The chronic myelogenous leukemia specific p210 protein is the product of the bcr/abl hybrid gene
3. The effect of interferon‐α on the proliferation of CML progenitor cells in vitro are not related to the precise position of the M‐BCR breakpoint
4. Molecular abnormalities of bcr and c‐abl in chronic myelogenous leukemia associated with a long chronic phase
5. The location of breakpoints within the breakpoint cluster region (bcr) of chromosome 22 in chronic myeoloid leukemia
6. Philadelphia chromosome breakpoints are located within a limited region, bcr, on chromosome 22
7. Structural organization of the bcr gene and its role in the Ph1 translocation
8. Clinical course of PCR in diagnosis and follow‐up of leukemia and lymphoma: report of the third workshop of the Molecular Biology/BMT Study Group
9. Improved results with PCR for chronic myeloid leukaemia
10. Confirmation and improvement of Sokal's prognostic classification of Ph1+ chronic myeloid leukemia: the value of early evaluation of the course of the disease
11. The position of the M‐BCR breakpoint does not predict the duration of the chronic phase or survival in chronic myeloid leukaemia
12. Non‐parametric estimation from incomplete observations
13. The molecular genetics of Philadelphia chromosome positive leukemias
14. Molecular genetic analysis of bcr breakpoint in Philadelphia chromosome rearrangements and correlation with prognosis and age of chronic myelogenous leukaemia patients
15. An assessment of chimeric transcript detection in CML patients after bone marrow transplantation
16. Does the breakpoint within the major breakpoint cluster region (M‐bcr) influence the duration of the chronic phase in chronic myeloid leukemia? An analytical comparison of current literature
17. The site of the breakpoint within the bcr is a prognostic factor in Philadelphia‐positive CML patients
18. The role of alternative splicing pattern of BCR/ABL transcripts in the generation of the blast crisis of chronic myeloid leukaemia
19. Relationship of bcr breakpoint to chronic phase duration, survival and blast crisis lineage in chronic myelogenous leukemia patients presenting in early chronic phase
20. A minute chromosome in human chronic granulocytic leukemia
21. Design and analysis of randomized clinical trials requiring prolonged observation of each patient (part II)
22. Breakpoint zone of bcr in chronic myelogenous leukemia does not correlate with disease phase or prognosis
23. A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
24. CML patients in blast crisis have breakpoints localized to a specific region of the BCR
25. Analysis of breakpoints within the bcr gene and their correlation with the clinical course of Philadelphia‐positive chronic myelogenous leukemia
26. Alternative splicing of RNAs transcribed from the human Abl gene and from the Bcr‐Abl fused gene
27. Prognostic discrimination in ‘good risk’ chronic granulocytic leukemia
28. Detection of specific sequences among DNA fragments separated by gel electrophoresis
29. Interferon‐alpha produces sustained cytogenetic responses in chronic myelogenous leukemia
30. Chromosome and bcr rearrangement in chronic myelogenous leukaemia and their correlation with clinical states and prognosis of the disease
31. Chronic myeloid leukemia
32. M‐BCR breakpoint location does not predict survival in Philadelpha chromosome‐positive chronic myeloid leukemia