Synthesis and Antiinflammatory and Analgesic Properties of 2-Amino-1 H-benzimidazole and 1,2-Dihydro-2-iminocycloheptimidazole Derivatives

Chemical and Pharmaceutical Bulletin

Volumn 41, Issue 2, 1993, Pages 301-309

  Taniguchi, KiYoshi ^a   Fujitsu, Takashi ^a,b   Shigenaga, Shinji ^a   Ogahara, Takatomo ^a   Matsuo, Masaaki ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b Fujisawa P   (Japan)

Author keywords

1,2 dihydro 2 iminocycloheptimidazole; 2 amino 1H benzimidazole; analgesic activity; antiinflammatory activity; timegadine 2 amino 4.5 dihydro 1H imidazole

Indexed keywords

1 (2 BENZOTHIAZOLYL) 2 CYCLOHEXYLIMINO 1,2 DIHYDROCYCLOHEPTIMIDAZOLE; ANALGESIC AGENT; BENZIMIDAZOLE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; TIARAMIDE; TIMEGADINE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; EDEMA; INFRARED SPECTROPHOTOMETRY; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; ORAL DRUG ADMINISTRATION; RAT; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; BENZIMIDAZOLES; COMPARATIVE STUDY; DINOPROSTONE; GUANIDINES; IMIDAZOLES; PIPERAZINES;

EID: 0027175627     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.41.301     Document Type: Article

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