Identification of α2-adrenoceptors and of non-adrenergic idazoxan binding sites in pancreatic islets from young and adult hamsters

International Journal of Biochemistry

Volumn 25, Issue 7, 1993, Pages 1077-1083

  Lacombe, Christiane ^a   Vlallard, Viviane ^a   Paris, Hervé ^a  

^a CHU RANGUEIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; ADRENALIN; ALPHA 2 ADRENERGIC RECEPTOR; BRIMONIDINE; CLONIDINE; IDAZOXAN; PRAZOSIN; YOHIMBINE;

AGE; ANIMAL TISSUE; ARTICLE; DRUG BINDING SITE; HAMSTER; NONHUMAN; PANCREAS ISLET;

ADRENERGIC ALPHA-AGONISTS; AGING; ANIMAL; BINDING SITES; DIOXANES; GLUCOSE; HAMSTERS; IDAZOXAN; INSULIN; ISLETS OF LANGERHANS; MALE; MESOCRICETUS; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, DRUG;

ANIMALIA; CRICETINAE;

EID: 0027175303     PISSN: 0020711X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0020-711X(93)90124-W     Document Type: Article

References (40)

1. Effects of α-adrenoceptor blockade by phentolamine on basal and stimulated insulin secretion in the mouse
2. Effects of α 1, α2- and β-adrenoceptor blockers on insulin secretion in the rat
3. Blockade of adrenaline-induced hyperglycaemia in the anaesthetized eat by continuous infusion of phentolamine and propranolol
4. Influence of development and reduction of fat stores on the antilipolytic α2-adrenoceptor in hamster adipocytes: comparison with adenosine and β-adrenergic lipolytic responses
5. Selective reduction of α2-adrenergic responsiveness in hamster adipose tissue during prolonged starvation
6. The α2-adrenoceptor antagonist efaroxan modulates K + ATP channels in insulin-secreting cells
7. Preponderance of β-adrenergic binding sites in pancreatic islet cells of the rat
8. Demonstration of α2-adrenergie receptors in rat pancreatic islets using radioligand binding
9. Evidence for imidazoline binding sites in basolateral membranes from rabbit kidney
10. The determination ofalpha-adrenergic receptor concentration on rat pancreatic islet cells
11. Adrenergic regulation of basal and serum glucose, NEFA and insulin levels
12. 3H]idazoxan bind to different sites on rabbit forebrain and kidney membranes
13. Effect of α-adrenoceptor agonists and antagonists on insulin secretory cells and pancreatic blood vessels: comparative study
14. Effect of α-adrenoceptor antagonists on clonidine-induced inhibition of insulin secretion by isolated pancreatic islets
15. 3H]idazoxan and of its methoxy derivative [3H]RX821002 labels additional non α2-adrenergic binding sites
16. Method for the isolation of intact islets of Langerhans from the rat pancreas
17. Protein measurement with the folin phenol reagent
18. Analysis of radioligand binding experiments: a collection of computer programs for the IBM-PC
19. Norepinephrine-induced insulin and substrate changes in normal man: incomplete reversal by phentolamine
20. Differences between the α2-adrenoceptor in rat submaxillary gland and the α2A- and α2B- adrenoceptor subtypes
21. 3H]Idazoxan and some other α2-adrenergic drugs also bind with high affinity non-adrenergic
22. Pancreatic neuroendocrinology: peripheral neural mechanisms in the regulation of the islets of Langerhans
23. Characterization of an imidazoline/guanidium receptive site distinct from the alpha2-adrenergic receptor
24. 3H]RX821002 and distribution along the villus-crypt axis
25. + channels in mouse pancreatic β-cells
26. + channels in mouse pancreatic β-cells
27. The insulin-secreting cell line, RIN m5F, expresses an alpha-2D adrenoceptor and non adrenergic idazoxan-binding sites
28. A role for α-adrenergic receptors in abnormal insulin secretion in diabetes mellitus
29. + channel in mouse pancreatic B cells
30. Photoperiodic control of adipocyte α2-adrenoceptors in Syrian hamsters: role of testosterone
31. Androgenic regulation of adipocyte α2-adrenoceptor expression in male and female Syrian hamsters: Proposed transcriptional mechanism
32. Differences in adrenergic recognition by pancreatic A and B cells
33. Phentolamine, a deceptive tool to investigate sympathetic nervous control of insulin release, Naunyn-Schmiedeberg's
34. An insulin releasing property of imidazoline derivatives is not limited to compounds that block α-adrenoceptors
35. Dual action ofclonidine on insulin release: suppression, but stimulation when α2-adrenoceptors are blocked
36. Identification of α2-adrenoceptors and non-adrenergic binding sites in rabbit colon epithelial cells
37. Islet cyclic AMP levels are not lowered during α2-adrenergic inhibition of insulin release. Studies with epinephrine and forskolin
38. 2+ and insulin release
39. Guanabenz, guanochio, guanoxan and idazoxan bind with high affinity to non-adrenergic sites in pig kidney membranes
40. Somatostatin and epinephrine decrease insulin messenger into nucleic acid in HIT cells through a pertussin toxin-sensitive mechanism