Aprotinin therapy in cardiac operations: A report on use in 41 cardiac centers in the United Kingdom

The Annals of Thoracic Surgery

Volumn 55, Issue 4, 1993, Pages 971-976

  Bidstrup, Ben P ^a,b,c,d,e   Harrison, Judy ^a,b,c,d,e   Royston, David ^a,b,c,d,e   Taylor, Kenneth M ^a,b,c,d,e   Treasure, Tom ^a,b,c,d,e  

^a WELLINGTON HOSPITAL   (United Kingdom)

^b HAREFIELD HOSPITAL   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d ST GEORGE S HOSPITAL   (United Kingdom)

^e Bayer plc UK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ;

ADULT; AGED; ARTICLE; BLEEDING; CHILD; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEART SURGERY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; APROTININ; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION; CARDIAC SURGICAL PROCEDURES; CAUSE OF DEATH; CHILD; FEMALE; GREAT BRITAIN; HOSPITAL MORTALITY; HUMAN; MALE; MIDDLE AGE; REOPERATION;

EID: 0027174797     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/0003-4975(93)90128-5     Document Type: Article

References (17)

1. Effect of aprotinin on need for blood transfusions after repeat open heart surgery
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3. Effect of aprotinin on need for blood transfusion in patients with septic endocarditis having open heart surgery
4. NIH Consensus Conference: perioperative red blood cell transfusion
5. Blood conservation techniques
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7. Prophylactic tranexamic acid decreases bleeding after cardiac operations
8. A trial of desmopressin (1-desamino-8-d-arginine vasopressin) to reduce blood loss in uncomplicated cardiac surgery
9. Treatment with desmopressin acetate to reduce blood loss after cardiac surgery
10. Effects of prostacyclin infusion on platelet activation and postoperative blood loss in coronary bypass
11. A prospective, randomized study of the effects of prostacyclin on platelets and blood loss during coronary bypass operations
12. Aprotinin in aspirin-pretreated patients
13. Aprotinin therapy for reoperative myocardial revascularization: a placebo-controlled study
14. Prosthetic valve endocarditis
15. Reduction of blood transfusion requirement in open heart surgery by administration of high dose aprotinin—preliminary results
16. Effects of high-dose aprotinin on blood loss, platelet function, fibrinolysis, complement, and renal function after cardiopulmonary bypass
17. Blood transfusion in cardiac surgery