Localization and production of plasminogen activator inhibitor-1 in human healthy and atherosclerotic arteries

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 13, Issue 7, 1993, Pages 1090-1100

  Lupu, Florea ^a   Bergonzelli, Gabriela E ^a   Heim, Dominik A ^a   Cousin, Elisabeth ^a   Genton, Claude Y ^a   Bachmann, Fedor ^a   Kruithof, Egbert K O ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Arterial wall; Atherosclerosis; Endothelial cells; Plasminogen activator inhibitor type 1; Smooth muscle cells; Vitronectin

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1; VITRONECTIN;

ARTERY ENDOTHELIUM; ARTERY THROMBOSIS; ARTERY WALL; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ARTERIES; ARTERIOSCLEROSIS; BLOOD PROTEINS; ENDOTHELIUM, VASCULAR; GLYCOPROTEINS; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICROSCOPY, ELECTRON; MUSCLE, SMOOTH, VASCULAR; PLASMINOGEN ACTIVATOR INHIBITOR 1; SUBCELLULAR FRACTIONS; SUPPORT, NON-U.S. GOV'T; VITRONECTIN;

EID: 0027172704     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.13.7.1090     Document Type: Article

References (29)

1. Engelberg H. Endothelium in health and disease. Semin Thromb Hemost. 1989;15:178-183.
2. Nachman RL. Thrombosis and atherosclerosis: molecular connections. Blood. 1992;79:1897-1906.
3. Bachmann F. Fibrinolysis. In: Verstraete M, Vermylen J, Lijnen R, Arnout J, eds. Thrombosis and Haemostasis. Leuven, Belgium: Leuven University Press; 1987:227-265.
4. Kruithof EKO. Plasminogen activator inhibitor 1: biochemical, biological and clinical aspects. Fibrinolysis. 1988;2(suppl 2):59-67.
5. Loskutoff DJ. Regulation of PAI-1 gene expression. Fibrinolysis. 1991;5:197-206.
6. Erickson LA, Fici GJ, Lund JE, Boyle TP, Polites HG, Marotti KR. Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene. Nature. 1990;346:74-76.
7. Levi M, Biemond BJ, Van Zonneveld A-J, ten Cate JW, Pannekoek H. Inhibition of plasminogen activator inhibitor-1 in promotion of endogenous thrombolysis and inhibition of thrombus extension in models of experimental thrombosis. Circulation. 1992; 85:305-312.
8. Klagsbrun M, Edelman ER. Biological and biochemical properties of fibroblast growth factors: implications for the pathogenesis of atherosclerosis. Arteriosclerosis. 1989;9:269-278.
9. Etingin OR, Hajjar DP, Hajjar KA, Harpel PC, Nachman RL. Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells: a potential mechanism in thrombogenesis. J Biol Chem. 1991;266:2459-2465.
10. Newman GR, Jasani B, Williams ED. A simple postembedding system for rapid demonstration of tissue antigens under the electron microscope. J Microsc. 1982;127:RP5-RP6.
11. Vacca LL. Double bridge techniques of immunocytochemistry. In: Bullock GR, Petrusz P, eds. Techniques in Immunocytochemistry. New York, NY: Academic Press; 1982:155-182.
12. Tapia FJ, Varndell IM, Probert L, De Mey J, Polak JM. Double immunogold staining method for simultaneous ultrastructural lo-calization of regulatory peptides. J Histochem Cytochem. 1983;31: 977-981.
13. Loskutoff DJ, Ny T, Sawdey M, Lawrence D. Fibrinolytic system of cultured endothelial cells: regulation by plasminogen activator inhibitor. J Cell Biochem. 1986;32:273-280.
14. Holland P. Localization of gene transcripts in embryo sections: in situ hybridization with RNA probes. In: Hogan B, Constantini F, Lacey E, eds. Manipulating the Mouse Embryo: A Laboratory Manual. New York: Cold Spring Harbor Laboratory, 1986:228-244.
15. Mimuro J, Loskutoff DJ. Purification of a protein from bovine plasma that binds to type 1 plasminogen activator inhibitor and prevents its interaction with extracellular matrix: evidence that the protein is vitronectin. J Biol Chem. 1989;264:936-939.
16. Seiffert D, Mimuro J, Schleef RR, Loskutoff DJ. Interactions between type 1 plasminogen activator inhibitor, extracellular matrix and vitronectin. Cell Differ Dev. 1990;32:287-292.
17. Schneiderman J, Sawdey MS, Keeton M, Bordin GM, Bernstein EF, Dilley RB, Loskutoff DJ. Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries. Proc Natl Acad Sci U S A. 1992;89:6998-7002.
18. Ross R. The pathogenesis of atherosclerosis: an update. N Engl J Med. 1986;314:488-500.
19. Rus HG, Niculescu F, Vlaicu R. Tumor necrosis factor-alpha in human arterial wall with atherosclerosis. Atherosclerosis. 1991;89: 247-254.
20. Arbustini E, Grosso M, Diegoli M, Pucci A, Bramerio M, Ardissino D, Angoli L, De Servi S, Bramucci E, Mussini A. Coronary atherosclerotic plaques with and without thrombus in ischemic heart syndromes: a morphologic, immunohistochemical, and biochemical study. Am J Cardiol. 1991;68:36B-50B.
21. Castellote JC, Grau E, Linde MA, Pujol-Moix N, Rutilant ML. Detection of both type 1 and type 2 plasminogen activator inhibitors in human monocytes. Thromb Haemost. 1990;63:67-71.
22. Wiman B, Almquist A, Siguardardottir O, Lindahl T. Plasminogen activator inhibitor (PAI) is bound to vitronectin in plasma. FEBS Lett. 1988;242:125-128.
23. Niculescu F, Rus HG, Porotiu D, Ghiurca V, Vlaicu R. Immunoelectron-microscopic localization of S-protein/vitronectin in human atherosclerotic wall. Atherosclerosis. 1989;78:197-203.
24. Seiffert D, Keeton M, Eguchi Y, Sawdey M, Loskutoff DJ. Detection of vitronectin mRNA in tissues and cells of the mouse. Proc Natl Acad Sci U S A. 1991;88:9402-9406.
25. Hetland G, Pettersen HB, Mollnes TE, Johnson E. S-protein is synthesized by human monocytes and macrophages in vitro. Scand J Immunol. 1989;29:15-21.
26. Tomasini BR, Mosher DF. Vitronectin. Prog Hemost Thromb. 1991;10P:269-305.
27. Lendon C, Born GVR, Davies MJ, Richardson PD. Plaque fissure: the link between atherosclerosis and thrombosis. Nouv Rev Fr Hematol. 1992;34:27-29.
28. Wilcox JN, Smith KM, Schwartz SM, Gordon D. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci U S A. 1989;86:2839-2843.
29. Laiho M, Keski Oja J. Growth factors in the regulation of pericellular proteolysis: a review. Cancer Res. 1989;49:2533-2553.