Determinants of Release Rate of Tetanus Vaccine from Polyester Microspheres

Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists

Volumn 10, Issue 7, 1993, Pages 945-953

  Alonso, Maria J ^a,b   Cohen, Smadar ^a,c   Park, Tae G ^a,d   Gupta, Rajesh K ^e   Siber, George R ^e   Langer, Robert ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^d TEMPLE UNIVERSITY   (United States)

^e MASSACHUSETTS DEPARTMENT OF PUBLIC HEALTH   (United States)

Author keywords

biodegradable microspheres; controlled release; poly(lactic glycolic acid); tetanus; vaccine delivery system

Indexed keywords

MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID; POLYMER; TETANUS TOXOID;

ANIMAL EXPERIMENT; ARTICLE; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; FEMALE; HYDROPHOBICITY; IMMUNE RESPONSE; IMMUNIZATION; MOUSE; NONHUMAN; PARTICLE SIZE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; IMMUNOGLOBULIN G; LACTATES; MICE; MICROSCOPY, ELECTRON; MICROSPHERES; MOLECULAR WEIGHT; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; POLYMERS; POROSITY; PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TETANUS TOXOID;

EID: 0027169876     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1023/A:1018942118148     Document Type: Article

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