Regulation of synthesis of complement proteins in HEp2 cells

Clinical Immunology and Immunopathology

Volumn 67, Issue 2, 1993, Pages 117-123

  Katz, Yitzhak ^a   Guterman, Mina ^a   Lahat, Eliezer ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0027167707     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1993.1053     Document Type: Article

References (35)

1. Alper, C. A., and Johnson, M. A., Human C’3: Evidence for the liver as the primary site of synthesis. Science 163, 286-288, 1969.
2. Alper, C. A., and Rosen, F. S., Genetics of the complement system. Adv. Hum. Genet. 7, 141-188, 1976.
3. Colten, H. R., Biosynthesis of the MHC-linked complement proteins (C2, C4 and factor B) by mononuclear phagocytes. Mol. Immunol. 19, 1279-1285, 1982.
4. Strunk, R. C., Whitehead, A. S., and Cole, F. S., Pretranslational regulation of the synthesis of the third component in human mononuclear phagocytes by the lipid A portion of lipopolysaccharide. J. Clin. Invest. 76, 985-990, 1985.
5. Katz, Y., and Strunk, R. C., Synovial fibroblast-like cells synthesize seven proteins of the complement system. Arthritis Rheum. 31, 1365-1370, 1988.
6. Strunk, R. C., Eidler, D. M., and Mason, R. J., Pulmonary alveolar type II epithelial cells synthesize and secrete proteins of the classical and alternative complement pathways. J. Clin. Invest. 81, 1419-1426, 1988.
7. Ripoche, J., Mitchell, J. A., Erdei, A., Madin, C., Moffatt, B., Mokoena, T., Gordon, S., and Sim, R. B., Interferon gamma induces synthesis of complement alternative pathway proteins by human endothelial cells in culture. J. Exp. Med. 168, 1917-1922, 1988.
8. Katz, Y., Cole, S. F., and Strunk, R. C., Synergism between gamma interferon and lipopolysaccharide for synthesis of factor B, but not C2, in human fibroblasts. J. Exp. Med. 167, 1-14, 1988.
9. Ohamian, S. H., and Borsos, T., Lysis of human cells by antibody and complement. II. Lack of correlation between the amount of C4 and C3 fixed and cell lysis. J. Immunol. 142, 1292-1295, 1975.
10. Durum, S. K., Schmidt, J. A., and Oppenheim, J. J., Interleukin-1: An immunological perspective. Annu. Rev. Immunol. 3, 263-287, 1985.
11. Feinman, R., Henriksen-De Stefano, D., Tsujimoto, M., and Vilcek, J., Tumor necrosis factor is an important mediator of tumor cell killing by human monocytes. J. Immunol. 138, 635-640, 1987.
12. 2/IL-6 genes in human fibroblasts. J. Immunol, 142, 3862-3867, 1989.
13. Perlmutter, D. H., Dinarello, C. A., Punsal, P. I., and Colten, H. R., Cachectin/tumor necrosis factor regulates hepatic acutephase gene expression. J, Clin. Invest. 78, 1349-1354, 1986.
14. Circolo, A., Pierce, G. F., Katz, Y., and Strunk, R. G., Antiinflammatory effects of polypeptide growth factors: Plateletderived growth factor, epidermal growth factor and fibroblast growth factor inhibit the cytokine-induced pathway activator factor B in human fibroblasts. J. Biol. Chem. 265, 5066-5071, 1990.
15. Moore, A. E., Sabachewsky, L., and Wallace Toolar, H., Culture characteristics of four permanent lines of human cancer cells. Cancer Res. 15, 598-602, 1955.
16. Kulics, J., Colten, H. R., and Perlmutter, D. H., Counterregulatory effects of interferon and endotoxin on expression of the human C4 genes. J. Clin. Invest. 85, 943-949, 1990.
17. Roberts, B. E., and Patterson, B. M., Effect of translation of tobacco mosaic virus RNA and rabbit globin 9S RNA in a cell-free system from commercial wheat germ. Proc. Natl. Acad. Sci. USA 70, 2330-2334, 1973.
18. Laemmli, U. K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227, 680-685, 1970.
19. Katz, Y., and Strunk, R. C., Synthesis and regulation of Cl inhibitor in human skin fibroblasts. J. Immunol. 142, 2041-2045, 1989.
20. Katz, Y., and Strunk, R. C., Synthesis and regulation of complement protein factor H in human skin fibroblasts. J. Immunol. 141, 559-563, 1988.
21. Morris, K. M., Aden, D. P., Knowles B., and Colten, H. R., Complement biosynthesis by the human hepatoma-derived cell line Hep G2. J. Clin. Invest. 70, 906-913, 1982.
22. Yeung Laiwah, A. C., Jones, L., Hamilton, A. O., and Whaley, K., Complement-subcomponent-Cl-inhibitor synthesis by human monocytes. Biockem. J. 226, 199-205, 1985.
23. Bensa, J. C., Reboul, A., and Colomb, M. G., Biosynthesis in vitro of complement subcomponents Clq, Cls and Cl inhibitor by resting and stimulated human monocytes. Biochem. J. 216, 385-392, 1983.
24. Strunk, R. C., Cole, F. S., Perlmutter, D. H., and Colten, H. R., Interferon increases expression of class III complement genes C2 and factor B in human monocytes and in murine fibroblasts transfected with human C2 and factor B genes. J. Biol. Chem. 260, 15280-15285, 1985.
25. Strunk, R. C., Whitehead, A. S., and Cole, F. S., Pretranslation regulation of the synthesis of the third component of complement in human mononuclear phagocytes by the lipid A protein of lipopolysaccharide. J. Clin. Invest. 76, 985-990, 1985.
26. Niemann, M. A., Kearney, J. F., and Volanakis, J. E., The use of monoclonal antibodies as probes of the three-dimensional structure of human complement factor D. J. Immunol. 132, 809-815, 1984.
27. Al-Adnani, M. D., and Me Gee, J. D., Clq production and secretion by fibroblasts. Nature (London) 263, 145-146, 1976.
28. Brooimans, R. A., van Der Ark, A. A. J., Buurman, W. A., Van Es, L. A., and Daha, M. R., Differential regulation of complement factor H and C3 production in human umbilical vein endothelial cells by IFN-7 and IL-1. J. Immunol. 144, (10), 3835-3840, 1990.
29. Bing, D. H., Spurlock, S. E., and Bern, M. M., Synthesis of the first component of complement by primary cultures of human tumors of the colon and urogenital tract and comparable normal tissue. Clin. Immunol. Immunopathol. 4, 341-351, 1975.
30. Morris, K. M., Colten, H. R., and Bing, D. H., The first component of complement: a quantitative comparison of its biosynthesis in culture by human epithelial and mesenchymal cells. J. Exp. Med. 148, 1007-1019, 1978.
31. Zuraw, B. L., and Lotz, M., Regulation of the hepatic synthesis of Cl inhibitor by the hepatic stimylatory factors interleukin 6 and interferon-?. J, Biol. Chem. 265, 12664-12670, 1990.
32. Heda, G. D., Mardente, S., Weiner, L., and Schmaier, A. H., Interferon-7 increased in vitro and in vivo expression of Cl inhibitor. Blood 75, 2401-2407, 1990.
33. Barash, I., Fishelson, Z., and Revel, M., Induction of complement factor B activity in human fibroblasts by IL-6/IFN-f2 and IFN-‘y. J. Biol. Regul. Homeost. Agents 3, 175-180, 1989.
34. Cicardi, M., Bergamaschini, L., Cugno, M., Hack, E., Agostoni, G., and Agostoni, A., Long-term treatment of hereditary angioedema with attenuated androgens: A survey of a 13-year experience. J. Allergy Clin. Immunol. 87, 768-773.
35. Ahrenstedt, O., Knutson, L., Nilsson, B., Nilsson-Ekdahl, K., Odlind, B., and Hallgren, R., Enhanced local production of complement components in the small intestine of patients with Crohn’s disease. N. Engl. J. Med. 322, 1345-1349, 1990.