Postpubertal outcome in girls diagnosed of premature pubarche during childhood: Increased frequency of functional ovarian hyperandrogenism

Journal of Clinical Endocrinology and Metabolism

Volumn 76, Issue 6, 1993, Pages 1599-1603

  Ibañez, Lourdes ^a   Potau, Neus ^a   Virdis, Raffaele ^b   Zampolli, Maria ^b   Terzi, Cesare ^b   Gussinyti, Miquel ^a   Carrascosa, Antonio ^a   Vicens Calvet, Enric ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF PARMA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; BIOCHEMICAL MARKER; ESTRADIOL; FOLLITROPIN; HYDROXYPROGESTERONE; LEUPRORELIN; LUTEINIZING HORMONE; PRASTERONE; PRASTERONE SULFATE; TESTOSTERONE;

ADOLESCENT; ANDROSTENEDIONE BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC TEST; FEMALE; HIRSUTISM; HUMAN; HYPERANDROGENISM; MENARCHE; OLIGOMENORRHEA; OVARY FUNCTION; OVARY POLYCYSTIC DISEASE; PHARMACOLOGICAL STIMULATION; PRECOCIOUS PUBERTY; PRIORITY JOURNAL; STEROID BLOOD LEVEL; STEROIDOGENESIS; TESTOSTERONE BLOOD LEVEL;

ANDROGENS; FEMALE; FOLLICLE STIMULATING HORMONE; HUMAN; INCIDENCE; LEUPROLIDE; LUTEINIZING HORMONE; OVARIAN DISEASES; OVARY; PUBERTY; PUBERTY, PRECOCIOUS; RETROSPECTIVE STUDIES; STEROIDS;

EID: 0027166906     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jcem.76.6.8501168     Document Type: Article

References (26)

1. Ibanez L, Virdis R, Potau N, et al. 1992 Natural history of premature pubarche. An auxological study. J Clin Endocrinol Metab. 74:254-257.
2. Saenger P, Reiter EO. 1992 Editorial: premature adrenarche: A normal variant of puberty? J Clin Endocrinol Metab. 74:236-238.
3. Yen SSC. 1986 Chronic anovulation caused by peripheral endocrine disorders. In: Yen SSC, Jaffe RB, eds. Reproductive endocrinology. Philadelphia: Saunders; pp 441-499.
4. Ibanez L, Potau N, Albisu M, et al. 1990 Post-puberal assessment in girls with premature pubarche: clinical, biochemical, and echo-graphic findings [Abstract], Horm Res. 33(Suppl 3):37.
5. Rosenfield RL. 1990 Hyperandrogenism in peripubertal girls. In: Mahoney CP, ed. Current issues in pediatric and adolescent endocrinology. Philadelphia: Saunders; pp 1333-1358.
6. Loughlin T, Cunningham S, Moore A, Culliton M, Smyth PPA, McKenna TJ. 1986 Adrenal abnormalities in polycystic ovary syndrome. J Clin Endocrinol Metab. 62:142-147.
7. Barnes RB, Rosenfield RL. 1989 Polycystic ovary syndrome: pathogenesis and treatment. Ann Intern Med. 110:386-399.
8. Barnes RB, Rosenfield RL, Burstein S, Ehrmann DA. 1989 Pituitary-ovarian responses to nafarelin in the polycystic ovary syndrome. N Engl J Med. 320:559-565.
9. Rosenfield RL, Barnes RB, Cara JF, Lucky AW. 1990 Disregulation of cytochrome P450cl7a as the cause of polycystic ovarian syndrome. Fertil Steril. 53:785-790.
10. Ehrmann DA, Rosenfield RL, Barnes RB, Brigell DF, Sheikh Z. 1992 Detection of functional ovarian hyperandrogenism in women with androgen excess. N Engl J Med. 327:157-162.
11. New MI, Lorenzen F, Lerner AJ, et al. 1983 Genotyping steroid 21-hydroxylase deficiency: hormonal reference data. J Clin Endocrinol Metab. 56:320-325.
12. Pang S, Lerner AJ, Stoner E, et al. 1985 Late-onset steroid 3β-hydroxysteroid dehydrogenase deficiency. 1. A cause of hirsutism in pubertal and postpubertal women. J Clin Endocrinol Metab. 60:428-439.
13. Temeck JW, Pang S, Nelson C, New MI. 1987 Genetic defects of steroidogenesis in premature pubarche. J Clin Endocrinol Metab. 64:609-617.
14. Adams J, Poison DW, Abdulwahid N, et al. 1985 Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotropin releasing hormone. Lancet. 2:1375-1379.
15. Ferriman D, Gallway JD. 1961 Clinical assessment of body hair growth in women. J Clin Endocrinol Metab. 21:1440-1447.
16. Abraham GE. 1977 Handbook of radioimmunoassay. In: Dekker M, ed. Clinical and biochemical analysis. New York: Academic Press; 5:591-656.
17. Siegel SF, Finegold DN, Lanes R, Lee PA. 1990 ACTH stimulation tests and plasma dehydroepiandrosterone-sulfate levels in women with hirsutism. N Engl J Med. 323:849-854.
18. Toscano V, Balducci R, Bianchi P, Mangiantini A, Sciarra F. 1990 Ovarian 17-ketosteroid reductase deficiency as a possible cause of polycystic ovarian disease. J Clin Endocrinol Metab. 71:288-292.
19. Adams J, Poison DW, Franks S. 1986 Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br Med J. 293:355-359.
20. Kim MH, Rosenfield RL, Hosseinian AH, Schneir HG. 1979 Ovarian hyperandrogenism with normal and abnormal histologic findings of the ovaries. Am J Obstet Gynecol. 134:445-452.
21. Ardaens Y, Robert Y, Lemaître L, Fossati P, Dewailly D. 1991 Polycystic ovarian disease: contribution of vaginal endosonography and reassessment of ultrasonic diagnosis. Fertil Steril. 55:1062-1068.
22. Rosenfield RL, Ehrmann DA, Barnes RB, Brigell DF, Chandler DW. 1991 Ovarian steroidogenic abnormalities in polycystic ovary syndrome: evidence for abnormal coordinate regulation of androgen and estrogen secretion. In: Dunaif A, Givens JR, Haseltine FP, Merriam GR, eds. Polycystic ovary syndrome. Boston: Blackwell; pp 83-110.
23. Lucky AW, Rosenfield RL, McGuire J, Rudy S, Heike J. 1986 Adrenal androgen hyperresponsiveness to adrenocorticotropin in women with acne and/or hirsutism: adrenal enzyme defects and exaggerated adrenarche. J Clin Endocrinol Metab. 62:840-848.
24. Rosenfield RL, Rich BH, Lucky AW. 1982 Adrenarche as a cause of benign pseudopuberty in boys. J Pediatr. 101:1005-1009.
25. Yen SSC. 1980 The polycystic ovary syndrome. Clin Endocrinol (Oxf). 12:177-208.
26. Rheaume E, Lachance Y, Zhao HF, et al. 1991 Structure and expression of a new complementary DNA encoding the almost exclusive 3-beta-hydroxysteroid dehydrogenase/delta 5-delta 4-iso-merase in human adrenals and gonads. Mol Endocrinol. 5:1147-1157.