K‐ras oncogene activation in lung adenocarcinomas from former smokers evidence that K‐ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung

Cancer

Volumn 72, Issue 2, 1993, Pages 432-438

  Westra, William H ^a,d   Slebos, Robbert J C ^a,d   Offerhaus, G Johan A ^a,d   Goodman, Steven N ^a,b,d   Evers, Siegina G ^a   Kensler, Thomas W ^c   Askin, Frederic B ^a,d   Rodenhuis, Sjoerd ^a   Hruban, Ralph H ^a,d  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d The Academic Medical Center ^*  (United States)

Author keywords

adenocarcinoma; carcinogen; K ras; lung neoplasm; oncogene; tobacco smoking

Indexed keywords

BENZO[A]PYRENE; TOBACCO SMOKE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; HUMAN; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SMOKING; SMOKING CESSATION;

ADENOCARCINOMA; AGED; COMPARATIVE STUDY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMAN; LUNG NEOPLASMS; MALE; MIDDLE AGE; POINT MUTATION; POLYMERASE CHAIN REACTION; SMOKING; TIME FACTORS;

EID: 0027166695     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/1097-0142(19930715)72:2<432::AID-CNCR2820720219>3.0.CO;2-#     Document Type: Article

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