The synthesis of modified oligonucleotides by the phosphoramidite approach and their applications

Tetrahedron

Volumn 49, Issue 28, 1993, Pages 6123-6194

  Beaucage, Serge L ^a   Iyer, Radhakrishnan P ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE;

DNA BINDING; DNA DEGRADATION; DNA REPAIR; DNA SYNTHESIS; GENE EXPRESSION; METHODOLOGY; PHOTOCHEMISTRY; REACTION ANALYSIS; REVIEW; RNA SYNTHESIS; SYNTHESIS; THERMODYNAMICS;

EID: 0027164483     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)87958-8     Document Type: Article

References (608)

1. Regio- and Stereospecific Synthesis of 7-Deazapurine 2′-deoxyribonucleosides and Incorporation of Nucleoside Isosteres into Oligonucleotides
2. Protein-DNA Recognition: The Interaction of lac cI and E.coli RNA Polymerase with Operators and Promoters
3. Oligodeoxynucleotides Containing Modified Bases
4. Polynuclear Aromatic Carcinogens.
5. Stereochemistry of Oligodeoxyribonucleotide Phosphotriesters
6. Phosphorothioate Oligodeoxynucleotide Analogues
7. Control of Gene Expression by Antisense and Antigene Oligonucleotide-Intercalator Conjugates
8. Chemically Modified Oligodeoxynucleotide Analogs as Regulators of Viral and Cellular Gene Expression
9. Phosphorothioate Oligomers — Inhibitors of Oncogene Expression in Tumor Cells and Tools for Gene Function Analysis
10. Oligonucleotide Analogues as Potential Chemotherapeutic Agents
11. Phosphorothioate Oligonucleotides
12. Thermodynamics of Antisense Oligonucleotide Hybridization
13. Inhibition of Gene Expression by Oligonucleotides
14. Heterocyclic Base Modifications in Nucleic Acids and Their Applications in Antisense Oligonucleotides
15. Application of Oligonucleotide Drugs for Cancer Prevention
16. Cellular Uptake and Anti-HIV Activity of Oligonucleotide and Their Analogs
17. The Hybridization Inhibition, or Antisense, Approach to the Chemotherapy of AIDS
18. Host-Guest Molecular Interactions: From Chemistry to Biology
19. Synthesis of Oligonucleotide Phosphorodithioates
20. Site-Specific Attachment of Labels to the DNA Backbone
21. Hydrophobized Antiviral Antibodies and Antisense Oligonucleotides
22. Non-ionic Antisense Oligonucleotides
23. Synthesis of Oligo-2′-deoxyribonucleoside Methyl Phosphonates
24. Psoralen-Derivatized Antisense Oligonucleoside Methyl Phosphonates
25. Antisense DNA Therapeutics — Neutral Analogs and Their Stereochemistry
26. 2′-O-Methyloligoribonucleotides: Synthesis and Applications
27. Oligo-[α]-Deoxyribonucleotides Covalently Linked to Intercalating Agents. A New Family of Sequence-specific Nucleic Acids Reagents.
28. α-Oligodeoxynucleotide Analogues.