Localization of rat brain binding sites for [3H]tomoxetine, an enantiomerically pure ligand for norepinephrine reuptake sites

Neuroscience Letters

Volumn 157, Issue 2, 1993, Pages 203-206

  Gehlert, Donald R ^a   Gackenheimer, Susan L ^a   Robertson, David W ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Antidepressant; Autoradiography; Locus coeruleus

Indexed keywords

ANTIDEPRESSANT AGENT; ATOMOXETINE; DESIPRAMINE; NORADRENALIN;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; CONTROLLED STUDY; LOCUS CERULEUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; BINDING SITES; DESIPRAMINE; FLUOXETINE; KINETICS; LIGANDS; MALE; NERVE TISSUE PROTEINS; NOREPINEPHRINE; PIPERAZINES; PROPYLAMINES; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0027162344     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(93)90737-6     Document Type: Article

References (10)

1. 3H]-Desipramine binding to rat brain tissue: binding to both noradrenaline uptake sites and sites not related to noradrenaline neurons
2. 3H]-mazindol autoradiography
3. 3H]Mazindol binding associated with neuronal dopamine and norepinephrine uptake sites
4. 3H]-mazindol autoradiography
5. 3H]desipramine binding associated with neuronal norepinephrine uptake sites in rat brain membranes
6. 3H]-desipramine
7. 3H]-desipramine to rat cerebral cortex: relationship to tricyclic antidepressant-induced inhibition of norepinephrine uptake
8. 3H]-Nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding
9. 3H]-Nisoxetine: a new radioligand for norepinephrine uptake sites in brain
10. A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain