Effects of interleukin-4 on human osteoblast-like cells

Bone and Mineral

Volumn 21, Issue 1, 1993, Pages 53-61

  Riancho, J A ^a   Zarrabeitia, M T ^a   Olmos, J M ^a   Amado, J A ^a   Gonzalez Macias, J ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

1,25(OH)2D3; 1,25 dihydroxyvitamin D3; Alkaline phosphatase; FCS; fetal calf serum; IL; interleukin; Interleukins; lipopolysaccharide; LPS; Osteoblasts; p nitrophenol; PNP; TNF; tumor necrosis factor

Indexed keywords

ALKALINE PHOSPHATASE; RECOMBINANT INTERLEUKIN 4;

ARTICLE; CELL DENSITY; DOSE RESPONSE; HUMAN; HUMAN CELL; OSTEOBLAST; PRIORITY JOURNAL;

EID: 0027161387     PISSN: 01696009     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-6009(08)80120-1     Document Type: Article

References (18)

1. Interleukin-4: a prototypic immunoregulatory lymphokine
2. Monoclonal antibodies block murine IL-4 receptor function
3. Fibroblasts inhibit mineralized bone nodule formation by rat marrow stromal cells in vitro
4. Subpopulations of marrow stromal cells share a variety of osteoblastic markers
5. Glucocorticoid regulation of alkaline phosphatase in the osteoblastic osteosarcoma cell line ROS 17/2.8
6. Interleukin-4 as a potent inhibitor of bone resorption
7. Osteoclast ontogeny and function
8. A soluble, high-affinity, interleukin-4-binding protein is present in the biological fluids of mice
9. Growth factors effect on bone-forming cells
10. Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon basal levels of gene expression, duration of exposure and bone matrix competency in normal rat osteoblast cultures
11. Effects of combining transforming growth factor Q and 1,25-dihydroxyvitamin D3 on differentiation of a human osteosarcoma (MG-63)
12. 2 vitamin D3
13. Interleukin-4 inhibits the differentiation of mouse myeloid leukemia MI cells induced by dexamethasone, D-factor/leukemia inhibitory factor and interleukin-6, but not by lα,25-dihydroxyvitamin D3
14. Cytokine receptors and signal transduction
15. IL-4 regulates c-kit proto-oncogen product expression in human mast and myeloid cells
16. Interleukin-6: an osteotropic factor?
17. Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes
18. Recombinant IL-4 inhibits IL-6 synthesis by adherent peripheral blood cells in vitro