Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times

BBA - Biomembranes

Volumn 1149, Issue 1, 1993, Pages 180-184

  Blume, G ^a   Cevc, G ^a   Crommelin, M D J A ^b   Bakker Woudenberg, I A J M ^c   Kluft, C ^d   Storm, G ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UTRECHT UNIVERSITY   (Netherlands)

^c ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^d TNO   (Netherlands)

Author keywords

Biodistribution; Cryptosome; Drug targeting; Liposome; Long circulating liposome; Plasminogen; Poly(ethylene glycol); Protein binding

Indexed keywords

LIPOSOME; MACROGOL; PLASMINOGEN; PLASMINOGEN[GLUTAMIC ACID]; UNCLASSIFIED DRUG;

ARTICLE; DRUG TARGETING; INTRAVENOUS DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN BINDING;

ANIMAL; FIBRIN; HALF-LIFE; MICE; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; PLASMINOGEN; POLYETHYLENE GLYCOLS; PROTEOLIPIDS; SUPPORT, NON-U.S. GOV'T;

EID: 0027157735     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0005-2736(93)90039-3     Document Type: Article

References (29)

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2. Characterization of the binding of plasminogen to fibrin surfaces: The role of carboxy-terminal lysines