5-Aza-2′-deoxycytidine: Cell differentiation and DNA methylation

Leukemia

Volumn 7, Issue SUPPL. MONOGR. 1, 1993, Pages 3-8

  Taylor, Shirley M ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; CYTOSINE; DNA METHYLTRANSFERASE; ENZYME INHIBITOR;

ADIPOCYTE; CARTILAGE CELL; CELL DIFFERENTIATION; CONFERENCE PAPER; DNA METHYLATION; EMBRYO; FIBROBLAST; GENE EXPRESSION; HUMAN; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; AZACITIDINE; CARTILAGE; CELL DIFFERENTIATION; CELL LINE; DNA; GENE EXPRESSION REGULATION; METHYLATION; MUSCLE PROTEINS; MYOD PROTEIN; PHENOTYPE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027154904     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Constantinides PG, Taylor SM, Jones PA. Phenotypic conversion of cultured mouse embryo cells by azapyrimidine nucleosides. Dev Biol 1978;66:57-71.
2. Taylor SM, Jones PA. Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 1979;17:771-779.
3. Taylor SM, Jones PA. Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine. J Cell Physiol 1982;111:187-194.
4. Sager R, Kovac P. Pre-adipocyte determination either by insulin or by 5-azacytidine. Proc Natl Acad Sci USA 1982;79:480-484.
5. Creusot P, Acs G, Christman JK. Inhibition of DNA methyltransferase and induction of Friend erythroleukemic cell differentiation by 5-azacytidine and 5-aza-2′deoxycytidine. J Biol Chem 1982;257:2041-2048.
6. Christman JK, Medelsohn N, Herzog D, Schneiderman N. Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells (HL60). Cancer Res 1983;43:763-769.
7. Jones PA, Taylor SM. Cellular differentiation, cytidine analogs and DNA methylation. Cell 1980;20:85-93.
8. Lassar AB, Paterson BM, Weintraub H. Transfection of a DNA locus that mediates the conversion of 10T1/2 fibroblasts to myoblasts. Cell 1986;47:649-656.
9. Davis RL, Weintraub H, Lassar AB. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 1987;51:987-1000.
10. Konieczny SF, Emerson CP Jr. 5-Azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: evidence for regulatory genes controlling determination. Cell 1984;38:791-800.
11. Michalowsky LA, Jones PA. Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2′-deoxycytidine resistance. Mol Cell Biol 1987;7:3076-3083.
12. Jones PA, Taylor SM, Mohandas T, Shapiro LJ. Cell cycle specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidine. Proc Natl Acad Sci USA 1982;79:1215-1219.
13. Ben-Hattar J, Beard P, Jiricny J. Cytosine methylation in CIF and SpI recognition sites of an HSV tk promoter: effects on transcription in vivo and factor binding in vitro. Nucleic Acids Res 1989;17:10179-10190.
14. Molloy PL, Watt F. DNA methylation and specific protein DNA interactions. Phil Trans R Soc Lond 1990;1235:267-275.
15. Taylor SM, Jones PA. Mechanism of action of eukaryotic DNA methyltransferase: use of 5-azacytosine containing DNA. J Mol Biol 1982;162:679-692.
16. Jones PA, Taylor SM. Hemimethylated duplex DNAs prepared from 5-azacytidine treated cells. Nucleic Acids Res 1981;9:2933-2947.
17. Osterman DG, DePillis GD, Wu JC, Matsuda A, Santi DV. 5-Fluorocytosine is a mechanism-based inhibitor of Hha1 DNA methyltransferase. Biochemistry 1988;27: 5204-5210.
18. Santi DV, Garrett CE, Barr PJ. On the mechanism of inhibition of DNA-cytosine methyltransferases by cytidine analogs. Cell 1983;33:9-10.
19. Bestor T. Cloning of a mammalian DNA methyltransferase. Gene 1988;74:9-12.
20. Bestor T, Laudano A, Mattaliano R, Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzyme is related to bacterial restriction methytransferases. J Mol Biol 1988;203:971-983.
21. Szyf M, Rouleau J, Theberg J, Bozovic, V. Induction of myogenic differentiation by an expression vector encoding the mouse DNA methyltransferase cDNA sequence in the antisense orientation. J Biol Chem 1992;267:12831-12836.
22. Ley TJ, DeSimone J, Anagou NB, Keller GH, Humphries RK, Turner PH, Young NS, Heller P, Nienhuis AW. 5-Azacytidine selectively increases a-globin synthesis in a patient with β+ thalassemia. New Eng J Med 1982;307: 1469-1475.
23. Harris M. Induction of thymidine kinase in enzyme-deficient Chinese hamster cells. Cell 1982;29:483-492.
24. Meehan RR, Lewis JD, McKay S, Kleiner EL, Bird AP. Identification of a mammalian protein that binds specifically to DNA containing methylated cytosines. Cell 1989;58:499-507.
25. Antequera F, Macleod D, Bird AP. Specific protection of methylated CpGs in mammalian nuclei. Cell 1989;58: 509-517.
26. Supakar PC, Weist D, Zhang D, Inamdar N, Zhang X-Y, Khan R, Erlich KC, Erlich M. Methylated DNA-binding protein is present in various mammalian cell types. Nucleic Acids Res 1988;16:8029-8044.
27. Davis RL, Cheng PF, Lassar AB, Weintraub H. The MyoD DNA binding domain contains a recognition code for muscle specific gene activation. Cell 1990;60:733-746.
28. Wright WE, Sassoon DA, Ling VK. Myogenin, a factor regulating myogenesis has a domain homologous to MyoD. Cell 1989;56: 607-617.
29. Braun T, Buschhausen-Denker G, Bober E, Tannich E, Arnold HH. A novel human muscle factor related to but distinct from myoD1 induces myogenic conversion in 10T1/2 fibroblasts. EMBO J 1989;8:701-709.
30. Benezra R, Davis RL, Lockshon D, Turner DL, Weintraub H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 1990;61:49-59.
31. Schafer BW, Blakely BT, Darlington GJ, Blau HM. Effect of cell history on response to helix-loop-helix family of myogenic regulators. Nature 1990;344:454-458.
32. Pinney DF, Pearson-White SH, Konieczny SF, Latham KE, Emerson CP Jr. Myogenic lineage determination and differentiation: evidence for a regulatory gene pathway. Cell 1988;53:781-793.