Vitamin E Consumption and the Risk of Coronary Disease in Women

New England Journal of Medicine

Volumn 328, Issue 20, 1993, Pages 1444-1449

  Stampfer, Meir J ^a,b   Hennekens, Charles H ^a   Manson, Joann E ^a   Colditz, Graham A ^a,b   Rosner, Bernard ^a   Willett, Walter C ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; CORONARY ARTERY DISEASE; CORONARY RISK; DEATH; DIET SUPPLEMENTATION; FEMALE; HEALTH CARE POLICY; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MEDICAL RECORD; PRIORITY JOURNAL; QUESTIONNAIRE; SMOKING; STROKE; VITAMIN INTAKE;

ADULT; CONFIDENCE INTERVALS; CORONARY DISEASE; FEMALE; FOLLOW-UP STUDIES; HUMAN; INCIDENCE; MIDDLE AGE; PROSPECTIVE STUDIES; RISK FACTORS; SUPPORT, U.S. GOV'T, P.H.S.; VITAMIN E;

EID: 0027154706     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199305203282003     Document Type: Article

References (55)

1. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL Beyond cholesterol: modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989; 320:915-924
2. Steinberg D, Witztum JL Lipoproteins and atherogenesis: current concepts. JAMA 1990; 264:3047-3052
3. Steinberg D Antioxidants and atherosclerosis: a current assessment. Circulation 1991; 84:1420-1425
4. Quinn MT, Parthasarathy S, Fong LG, Steinberg D Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc Natl Acad Sci U S A 1987; 84:2995-2998
5. Quinn MT, Parthasarathy S, Steinberg D Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of low-density lipoprotein. Proc Natl Acad Sci U S A 1985; 82:5949-5953
6. Morel DW, DiCorleto PE, Chisolm GM Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation. Arteriosclerosis 1984; 4:357-364
7. Kugiyama K, Kerns SA, Morrisett JD, Roberts R, Henry PD Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature 1990; 344:160-162
8. Palinski W, Rosenfeld ME, Yla-Herttuala S, Low-density lipoprotein undergoes oxidative modification in vivo. Proc Natl Acad Sci U S A 1989; 86:1372-1376
9. Rosenfeld ME, Palinski W, Yla-Herttuala S, Butler S, Witztum JL Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits. Arteriosclerosis 1990; 10:336-349
10. Yla-Herttuala S, Palinski W, Rosenfeld ME, Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J Clin Invest 1989; 84:1086-1095
11. Salonen JT, Yla-Herttuala S, Yamamoto R, Autoantibody against oxidised LDL and progression of carotid atherosclerosis. Lancet 1992; 339:883-887
12. Stringer MD, Gorog PG, Freeman A, Kakkar VV Lipid peroxides and atherosclerosis. BMJ 1989; 298:281-284
13. Regnstrom J, Nilsson J, Tornvall P, Landou C, Hamsten A Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet 1992; 339:1183-1186
14. Stocker R, Frei B. Endogenous antioxidant defenses in human blood plasma. In: Sies H, ed. Oxidative stress: oxidants and antioxidants. Orlando, Fla.: Academic Press, 1991:213-43.
15. Packer L Protective role of vitamin E in biological systems. Am J Clin Nutr 1991; 53: Suppl: 1050S-1055S
16. Boscoboinik D, Szewczyk A, Hensey C, Azzi A Inhibition of cell proliferation by alpha-tocopherol: role of protein kinase C. J Biol Chem 1991; 266:6188-6194
17. Esterbauer H, Dieber-Rotheneder M, Striegl G, Waeg G Role of vitamin E in preventing the oxidation of low-density lipoprotein. Am J Clin Nutr 1991; 53: Suppl: 314S-321S
18. Princen HMG, von Poppel G, Vogelezang C, Buytenhek R, Kok FJ Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro: effect of cigarette smoking. Arterioscler Thromb 1992; 12:554-562
19. Livingstone PD, Jones C Treatment of intermittent claudication with vitamin E. Lancet 1958; 2:602-604
20. Williams HTG, Fenna D, Macbeth RA Alpha tocopherol in the treatment of intermittent claudication. Surg Gynecol Obstet 1971; 132:662-666
21. DeMaio SJ, King SB III, Lembo NJ, Vitamin E supplementation, plasma lipids and incidence of restenosis after percutaneous transluminal coronary angioplasty (PTCA). J Am Coll Nutr 1992; 11:68-73
22. Haeger K Long-time treatment of intermittent claudication with vitamin E. Am J Clin Nutr 1974; 27:1179-1181
23. Gillilan RE, Mondell B, Warbasse JR Quantitative evaluation of vitamin E in the treatment of angina pectoris. Am Heart J 1977; 93:444-449
24. Stampfer MJ, Colditz GA, Willett WC, Postmenopausal estrogen therapy and cardiovascular disease: ten-year follow-up from the Nurses' Health Study. N Engl J Med 1991; 325:756-762
25. Willett WC, Stampfer MJ, Colditz GA, Rosner BA, Hennekens CH, Speizer FE Dietary fat and the risk of breast cancer. N Engl J Med 1987; 316:22-28
26. Willett WC, Stampfer MJ, Underwood BA, Speizer FE, Rosner BR, Hennekens CH Validation of a dietary questionnaire with plasma carotenoid and alpha-tocopherol levels. Am J Clin Nutr 1983; 38:631-639
27. Willett WC, Sampson L, Stampfer MJ, Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 1985; 122:51-65
28. Willett WC, Stampfer MJ Total energy intake: implications for epidemiologic analyses. Am J Epidemiol 1986; 124:17-27
29. Colditz GA, Willett WC, Stampfer MJ, The influence of age, relative weight, smoking, and alcohol intake on the reproducibility of a dietary questionnaire. Int J Epidemiol 1987; 16:392-398
30. Willett WC, Sampson L, Browne ML, The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol 1988; 127:188-199
31. Stryker WS, Kaplan LA, Stein EA, Stampfer MJ, Sober A, Willett WC The relation of diet, cigarette smoking, and alcohol consumption to plasma beta-carotene and alpha-tocopherol levels. Am J Epidemiol 1988; 127:283-296
32. Hunter DJ, Sampson L, Stampfer MJ, Colditz GA, Rosner B, Willett WC Variability in portion sizes of commonly consumed foods among a population of women in the United States. Am J Epidemiol 1988; 127:1240-1249
33. Salvini S, Hunter DJ, Sampson L, Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol 1989; 18:858-867
34. Romieu I, Stampfer MJ, Stryker WS, Food predictors of plasma beta-carotene and alpha-tocopherol: validation of a food frequency questionnaire. Am J Epidemiol 1990; 131:864-876
35. Willett WC. Nutritional epidemiology. New York: Oxford University Press, 1990.
36. Willett WC, Stampfer MJ, Underwood BA, Taylor JO, Hennekens CH Vitamins A, E, and carotene: effects of supplementation on their plasma levels. Am J Clin Nutr 1983; 38:559-566
37. IHD registers: report of the fifth working group. Copenhagen, Denmark: World Health Organization, 1971.
38. Stampfer MJ, Willett WC, Speizer FE, Test of the National Death Index. Am J Epidemiol 1984; 119:837-839
39. Walker AE, Robins M, Weinfeld FD The National Survey of Stroke: clinical findings. Stroke 1981; 12: Suppl 1: I-13
40. Rothman KJ, Boice JD Jr. Epidemiologic analysis with a programmable calculator. Washington, D.C.: Government Printing Office, 1979. (NIH publication no. (PHS) 70-1649.)
41. Cox DR Regression models and life-tables. J R Stat Soc [B] 1972; 34:187-220
42. Colditz GA, Martin P, Stampfer MJ, Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. Am J Epidemiol 1986; 123:894-900
43. Colditz GA, Stampfer MJ, Willett WC, Rosner B, Speizer FE, Hennekens CH A prospective study of parental history of myocardial infarction and coronary heart disease in women. Am J Epidemiol 1986; 123:48-58
44. Stampfer MJ, Colditz GA, Willett WC, Rosner B, Speizer FE, Hennekens CH. Coronary heart disease risk factors in women: the Nurses' Health Study experience. In: Eaker E, Packard B, Wenger NK, Clarkson TB, Tyroler HA, eds. Coronary heart disease in women. New York: Haymarket-Doyma, 1987:112-6.
45. Colditz GA, Nurses' Health Study Research Group. The Nurses' Health Study: findings during 10 years of follow-up of a cohort of U.S. women. Curr Probl Obstet Gynecol Fertil 1990; 13:129-174
46. Stampfer MJ, Malinow MR, Willett WC, A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA 1992; 268:877-881
47. Kagan VE, Serbinova EA, Forte T, Scita G, Packer L Recycling of vitamin E in human low density lipoproteins. J Lipid Res 1992; 33:385-397
48. Jialal I, Grundy SM Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein. J Lipid Res 1992; 33:899-906
49. Verlangieri AJ, Bush MJ Effects of d-alpha-tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr 1992; 11:131-138
50. Gey KF, Brubacher GB, Stahelin HB Plasma levels of antioxidant vitamins in relation to ischemic heart disease and cancer. Am J Clin Nutr 1987; 45:1368-1377
51. Salonen JT, Salonen R, Seppanen K, Relationship of serum selenium and antioxidants to plasma lipoproteins, platelet aggregability and prevalent ischaemic heart disease in Eastern Finnish men. Atherosclerosis 1988; 70:155-160
52. Riemersma RA, Wood DA, Macintyre CCA, Elton RA, Gey KF, Oliver MF Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene. Lancet 1991; 337:1-5
53. Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA, Willett WC Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 1993; 328:1450-1456
54. Bendich A, Machlin LJ Safety of oral intake of vitamin E. Am J Clin Nutr 1988; 48:612-619
55. Women's Health Study Research Group. The Women's Health Study: summary of the study design. J Myocard Ischemia 1992; 4:27-29