Plasminogen activator inhibitor-1 gene-deficient mice: I. generation by homologous recombination and characterization

Journal of Clinical Investigation

Volumn 92, Issue 6, 1993, Pages 2746-2755

  Carmeliet, Peter ^a,b   Kieckens, Lena ^a,b   Schoonjans, Luc ^b   Ream, Beverly ^a   Van Nuffelen, Ann ^a,b   Prendergast, George ^c   Cole, Michael ^c   Bronson, Roderick ^d   Collen, Désiré ^b   Mulligan, Richard C ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c PRINCETON UNIVERSITY   (United States)

^d TUFTS UNIVERSITY   (United States)

Author keywords

Development; Embryonic stem cells; Fertility; Fibrinolysis; Gene targeting

Indexed keywords

ENDOTOXIN; IODINE 125; PLASMINOGEN ACTIVATOR INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO CELL; FEMALE; FIBRINOLYSIS; GENE DELETION; GENE DISRUPTION; GENE TARGETING; GENETIC RECOMBINATION; HISTOPATHOLOGY; IMMUNOCYTOCHEMISTRY; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; ORGANOGENESIS; PRIORITY JOURNAL; REPRODUCTION; SOUTHERN BLOTTING; STEM CELL;

ANIMAL; BASE SEQUENCE; BLOTTING, SOUTHERN; CELLS, CULTURED; CODON; DNA; DNA PRIMERS; DNA, COMPLEMENTARY; EMBRYO; FEMALE; GENE DELETION; GENOMIC LIBRARY; HOMOZYGOTE; KIDNEY; KIDNEY GLOMERULUS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; RESTRICTION MAPPING; STEM CELLS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0027144754     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116892     Document Type: Article

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