Effects of housing, restraint and chronic treatments with mCPP and sertraline on behavioural responses to mCPP

Psychopharmacology

Volumn 113, Issue 2, 1993, Pages 262-268

  Kennedy, A J ^a   Gibson, E L ^a   O'Connell, M T ^a   Curzon, G ^a  

^a Institute of Neurology Queen Square ^*  (United Kingdom)

Author keywords

5 HT1C receptor; Anxiety; Feeding; Locomotion; m Chlorophenylpiperazine; Sertraline

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; ANTIDEPRESSANT AGENT; SEROTONIN 1C RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; BEHAVIOR; CONTROLLED STUDY; FEEDING; HOUSING; HYPOPHAGIA; IMMOBILIZATION STRESS; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SOCIAL ENVIRONMENT; SOCIAL INTERACTION;

1-NAPHTHYLAMINE; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; EATING; HOUSING, ANIMAL; INTERPERSONAL RELATIONS; MALE; MOTOR ACTIVITY; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; RESTRAINT, PHYSICAL; SEROTONIN AGONISTS; SEROTONIN UPTAKE INHIBITORS; SERTRALINE; STRESS, PSYCHOLOGICAL;

EID: 0027144492     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/BF02245708     Document Type: Article

References (38)

1. Long term administration of m-chlorophenylpiperazine to rats does not alter functional sensitivity of either presynaptic or postsynaptic 5-HT1A receptors
2. Mianserin-induced 5-HT2 receptor downregulation results in anxiolytic effects in the elevated plus-maze test
3. Attenuation of 5-HT1A and 5-HT2 but not 5-HT1C receptor mediated behaviour in rats following chronic treatment with 5-HT receptor agonists, antagonists or anti-depressant
4. Central serotonin receptors: effector systems, physiological roles and regulation
5. mCPP: a tool for studying behavioural responses associated with 5-HT1C receptors
6. Chronic treatment with metachlorophenylpiperazine (m-CPP) alters behavioural and cerebral metabolic responses to the serotonin agonists m-CPP and quipazine but not 8-hydroxy-2 (di-N-propylamino) tetralin
7. Distribution of serotonin 5-HT1C receptor mRNA in adult rat brain
8. Effects of chronic fluoxetine treatment on behavioural and neuroendocrine responses to metachlorophenylpiperazine
9. Functional correlates of serotonin 5-HT1 recognition sites
10. The 5-HT receptor family: ligands, distribution and receptor effector coupling
11. Infusion of the 5-hydroxytryptamine agonists RU 24969 and TFMPP into the paraventricular nucleus of the hypothalamus causes hypophagia
12. 5-HT1C receptor antagonists have anxiolytic-like actions in the rat social interaction model
13. Evidence that mCPP may have behavioural effects mediated by central 5-HT1C receptors
14. Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 requires 5-HT1B receptors
15. Potencies of antagonists indicate that 5-HT1C receptors mediate 1-3(chlorophenyl)piperazine-induced hypophagia
16. Anxiogenic-like effects of mCPP and TFMPP in animal models are opposed by 5-HT1C receptor antagonists
17. Effects of sertraline and citalopram given repeatedly on the responsiveness of 5-HT receptor subpopulations
18. Clinical experience with serotonin reuptake inhibiting antidepressants
19. Serotonin-selective arylpiperazines with neuroendocrine, behavioural, temperature and cardiovascular effects in humans
20. The pharmacology of human anxiety
21. Serotonin receptors in the human brain-III Autoradiographic mapping of serotonin-I receptors
22. Regulation of 5-HT2 receptors in rat cortex. Studies with a putative selective agonist and an antagonist
23. Novel regulation of 5-HT1C receptors
24. Regulation of 5-HT2 and 5-HT1C serotonin receptor levels. Methodology and mechanisms
25. m-Chlorophenylpiperazine: a central serotonin agonist causing powerful anorexia in rats
26. Adaptive regulation of central serotonin receptors linked to phosphoinositide hydrolysis
27. Sertr aline-induced desensitization of the serotonin 5-HT2 receptor transmembrane signaling system
28. 5-Hydroxytryptamine receptor “families.”
29. Development of selective tolerance to the serotonin behavioural syndrome and suppression of locomotor activity after repeated administration of either 5-MeODMT or mCPP
30. High performance liquid chromatographic method for the analysis of plasma m-chlorophenylpiperazine
31. Long-term administration of m-chlorophenylpiperazine (mCPP) to rats induces changes in serotonin receptor binding, dopamine levels and locomotor activity without altering prolactin and corticosterone secretion
32. Anxiogenic-like effect of infusing 1-(3-chlorophenyl)piperazine (mCPP) into the hippocampus
33. Serotonergic responsivity in obsessive-compulsive disorders: effects of chronic clomipramine treatment