Comparison of the Pharmacokinetics of E2020, A New Compound for Alzheimer's Disease, in Healthy Young and Elderly Subjects

The Journal of Clinical Pharmacology

Volumn 33, Issue 11, 1993, Pages 1086-1091

  Ohnishi, Akihiro ^a   Mihara, Mitsuo ^b,d   Kamakura, Hirotoshi ^a   Tomono, Yoshiro ^b,d   Hasegawa, Jiro ^b,d   Yamazaki, Katsuhiko ^c   Morishita, Nobumichi ^b,d   Tanaka, Teruji ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c EISAI CO LTD   (Japan)

^d Department of Clinical Pharmacology and Biostatistics ^*

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DONEPEZIL; DRUG METABOLITE; PLASMA PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG URINE LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ADULT; AGED; AGING; ALZHEIMER DISEASE; CHOLINESTERASE INHIBITORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPARATIVE STUDY; FEMALE; HALF-LIFE; HUMAN; INDANS; MALE; METABOLIC CLEARANCE RATE; PIPERIDINES; PROTEIN BINDING;

EID: 0027141935     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/j.1552-4604.1993.tb01945.x     Document Type: Article

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